The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway von Ratsimandresy, Rojo A, Indramohan, Mohanalaxmi, Dorfleutner, Andrea, Stehlik, Christian

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The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages von Chu, Lan H., Indramohan, Mohanalaxmi, Ratsimandresy, Rojo A., Gangopadhyay, Anu, Morris, Emily P., Monack, Denise M., Dorfleutner, Andrea, Stehlik, Christian

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The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease von de Almeida, Lucia, Khare, Sonal, Misharin, Alexander V., Patel, Rajul, Ratsimandresy, Rojo A., Wallin, Melissa C., Perlman, Harris, Greaves, David R., Hoffman, Hal M., Dorfleutner, Andrea, Stehlik, Christian

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An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology von Ratsimandresy, Rojo A, Dorfleutner, Andrea, Stehlik, Christian

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NLRP3 licenses NLRP11 for inflammasome activation in human macrophages von Gangopadhyay, Anu, Devi, Savita, Tenguria, Shivendra, Carriere, Jessica, Nguyen, Huyen, Jäger, Elisabeth, Khatri, Hemisha, Chu, Lan H., Ratsimandresy, Rojo A., Dorfleutner, Andrea, Stehlik, Christian

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The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation von Ratsimandresy, Rojo A., Chu, Lan H., Khare, Sonal, de Almeida, Lucia, Gangopadhyay, Anu, Indramohan, Mohanalaxmi, Misharin, Alexander V., Greaves, David R., Perlman, Harris, Dorfleutner, Andrea, Stehlik, Christian

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Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation von Dagvadorj, Jargalsaikhan, Mikulska-Ruminska, Karolina, Tumurkhuu, Gantsetseg, Ratsimandresy, Rojo A., Carriere, Jessica, Andres, Allen M., Marek-Iannucci, Stefanie, Song, Yang, Chen, Shuang, Lane, Malcolm, Dorfleutner, Andrea, Gottlieb, Roberta A., Stehlik, Christian, Cassel, Suzanne, Sutterwala, Fayyaz S., Bahar, Ivet, Crother, Timothy R., Arditi, Moshe

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The PYRIN domain–only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses von Khare, Sonal, Ratsimandresy, Rojo A, de Almeida, Lúcia, Cuda, Carla M, Rellick, Stephanie L, Misharin, Alexander V, Wallin, Melissa C, Gangopadhyay, Anu, Forte, Eleonora, Gottwein, Eva, Perlman, Harris, Reed, John C, Greaves, David R, Dorfleutner, Andrea, Stehlik, Christian

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POP1 inhibits MSU-induced inflammasome activation and ameliorates gout von de Almeida, Lucia, Devi, Savita, Indramohan, Mohanalaxmi, Huang, Qi-Quan, Ratsimandresy, Rojo A, Pope, Richard M, Dorfleutner, Andrea, Stehlik, Christian

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Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis von Desallais, Lucille, Avouac, Jérôme, Fréchet, Maxime, Elhai, Muriel, Ratsimandresy, Rojo, Montes, Matthieu, Mouhsine, Hadley, Do, Hervé, Zagury, Jean-François, Allanore, Yannick

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Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening von Mouhsine, Hadley, Guillemain, Hélène, Moreau, Gabriel, Fourati, Najla, Zerrouki, Chouki, Baron, Bruno, Desallais, Lucille, Gizzi, Patrick, Ben Nasr, Nesrine, Perrier, Julie, Ratsimandresy, Rojo, Spadoni, Jean-Louis, Do, Hervé, England, Patrick, Montes, Matthieu, Zagury, Jean-François

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Genomewide Association Study of a Rapid Progression Cohort Identifies New Susceptibility Alleles for AIDS (ANRS Genomewide Association Study 03) von Le Clerc, Sigrid, Limou, Sophie, Coulonges, Cédric, Carpentier, Wassila, Dina, Christian, Taing, Lieng, Delaneau, Olivier, Labib, Taoufik, Sladek, Rob, Deveau, Christiane, Guillemain, Hélène, Ratsimandresy, Rojo, Montes, Matthieu, Spadoni, Jean-Louis, Therwath, Amu, Schächter, François, Matsuda, Fumihiko, Gut, Ivo, Lelièvre, Jean-Daniel, Lévy, Yves, Froguel, Philippe, Delfraissy, Jean-François, Hercberg, Serge, Zagury, Jean-François

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1137 ELEVATED OSM/OSMR EXPRESSION IN INFLAMED MUCOSAL TISSUE REFLECTS AN INFLAMMATORY CASCADE MEDIATED BY NEUTROPHIL:STROMAL INTERACTIONS ASSOCIATED WITH RESIDUAL DISEASE IN TREATM... von Eshghi, Shadi, Hackney, Jason A., Onabajo, Olusegun, Ratsimandresy, Rojo A., Keir, Mary, Quintanilla, Luis, Mazrooei, Parisa, Shi, Yongchang, Wang, Jerry, Kenigsberg, Ephraim, Nguyen, Allen, Gubatan, John Mark, Rogalla, Stephan, Holman, Derek, Au-Yeung, Amelia, Takahashi, Chikara, O'Gorman, William, Rhee, Horace, McBride, Jacqueline M.

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The oxidized phospholipid oxPAPC ameliorates septic shock by targeting the non-canonical inflammasome in macrophages von CHU, LAN H., Indramohan, Mohanalaxmi, Ratsimandresy, Rojo A., Gangopadhyay, Ạnu, Morris, Emily P., Monack, Denise M., Dorfleutner, Andrea, Stehlik, Christian

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Genomewide Association Study of an AIDS-Nonprogression Cohort Emphasizes the Role Played by HLA Genes (ANRS Genomewide Association Study 02) von Limou, Sophie, Le Clerc, Sigrid, Coulonges, Cédric, Carpentier, Wassila, Dina, Christian, Delameau, Olivier, Labib, Taoufik, Taing, Lieng, Sladek, Rob, Deveau, Christiane, Ratsimandresy, Rojo, Montes, Matthieu, Spadoni, Jean-Loius, Leliè, Jean-Daniel, Lévy, Yves, Therwath, Amu, Schächter, François, Matsuda, Fumihiko, Gut, Ivo, Froguel, Philippe, Delfraissy, Jean-François, Hercberg, Serge, Zagury, Jean-François

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Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys von Desallais, Lucille, Bouchez, Caroline, Mouhsine, Hadley, Moreau, Gabriel, Ratsimandresy, Rojo, Montes, Matthieu, Do, Hervé, Quintin-Colonna, Françoise, Zagury, Jean-François

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Active immunization against IL-23p19 improves experimental arthritis von Ratsimandresy, Rojo Anthony, Duvallet, Emilie, Assier, Eric, Semerano, Luca, Delavallée, Laure, Bessis, Natacha, Zagury, Jean-François, Boissier, Marie-Christophe

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POP3 is a novel inhibitor of ALR inflammasomes and controls host defense to DNA virus infections (INM6P.411) von Stehlik, Christian, Khare, Sonal, Ratsimandresy, Rojo, de Almeida, Lúcia, Cuda, Carla, Rellick, Stephanie, Misharin, Alexander, Wallin, Melissa, Gangopadhyay, Anu, Forte, Eleonora, Gottwein, Eva, Perlman, Harris, Reed, John, Greaves, David, Dorfleutner, Andrea

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The PYRIN domain-only protein POP3 inhibits AIM2-like receptor inflammasomes and regulates responses to DNA virus infections von Khare, Sonal, Ratsimandresy, Rojo A., de Almeida, Lúcia, Cuda, Carla M., Rellick, Stephanie L., Misharin, Alexander V., Wallin, Melissa C., Gangopadhyay, Anu, Forte, Eleonora, Gottwein, Eva, Perlman, Harris, Reed, John C., Greaves, David R., Dorfleutner, Andrea, Stehlik, Christian

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METHODS FOR TREATING PULMONARY FIBROTIC DISEASES OR DISORDERS WITH AN ANTI ONCOSTATIN M RECEPTOR BETA ANTIBODY von WILSON, Mark Stephen, RATSIMANDRESY, Rojo A, GALANTER, Joshua Mark, PAN, Lin, YOSHIDA, Kenta

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