The Chemical Biology of Ferroptosis in the Central Nervous System von Ratan, Rajiv R.

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Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis von Zille, Marietta, Karuppagounder, Saravanan S, Chen, Yingxin, Gough, Peter J, Bertin, John, Finger, Joshua, Milner, Teresa A, Jonas, Elizabeth A, Ratan, Rajiv R

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Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate von Sleiman, Sama F, Henry, Jeffrey, Al-Haddad, Rami, El Hayek, Lauretta, Abou Haidar, Edwina, Stringer, Thomas, Ulja, Devyani, Karuppagounder, Saravanan S, Holson, Edward B, Ratan, Rajiv R, Ninan, Ipe, Chao, Moses V

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Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases von Rroji, Orjon, Kumar, Amit, Karuppagounder, Saravanan S., Ratan, Rajiv R.

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Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways von Siddiq, Ambreena, Aminova, Leila R, Troy, Carol M, Suh, Kyungsun, Messer, Zachary, Semenza, Gregg L, Ratan, Rajiv R

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Wet and dry spell characteristics of global tropical rainfall von Ratan, R., Venugopal, V.

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Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice von Ferrante, Robert J, Kubilus, James K, Lee, Junghee, Ryu, Hoon, Beesen, Ayshe, Zucker, Birgit, Smith, Karen, Kowall, Neil W, Ratan, Rajiv R, Luthi-Carter, Ruth, Hersch, Steven M

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Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease von Kaidery, Navneet Ammal, Banerjee, Rebecca, Yang, Lichuan, Smirnova, Natalya A, Hushpulian, Dmitry M, Liby, Karen T, Williams, Charlotte R, Yamamoto, Masayuki, Kensler, Thomas W, Ratan, Rajiv R, Sporn, Michael B, Beal, M Flint, Gazaryan, Irina G, Thomas, Bobby

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Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition: Robust New Target or Another Big Bust for Stroke Therapeutics? von Karuppagounder, Saravanan S, Ratan, Rajiv R

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Derivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in rats von Ferguson, Adam R, Irvine, Karen-Amanda, Gensel, John C, Nielson, Jessica L, Lin, Amity, Ly, Johnathan, Segal, Mark R, Ratan, Rajiv R, Bresnahan, Jacqueline C, Beattie, Michael S

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Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury von Huie, J. R., Ferguson, A. R., Kyritsis, N., Pan, J. Z., Irvine, K.-A., Nielson, J. L., Schupp, P. G., Oldham, M. C., Gensel, J. C., Lin, A., Segal, M. R., Ratan, R. R., Bresnahan, J. C., Beattie, M. S.

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Neuroprotective Effects of Phenylbutyrate in the N171-82Q Transgenic Mouse Model of Huntington's Disease von Gardian, Gabriella, Browne, Susan E., Choi, Dong-Kug, Klivenyi, Peter, Gregorio, Jason, Kubilus, James K., Ryu, Hoon, Langley, Brett, Ratan, Rajiv R., Ferrante, Robert J., Beal, M. Flint

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The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease von Aimé, Pascaline, Karuppagounder, Saravanan S., Rao, Apeksha, Chen, Yingxin, Burke, Robert E., Ratan, Rajiv R., Greene, Lloyd A.

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Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke von Speer, Rachel E., Karuppagounder, Saravanan S., Basso, Manuela, Sleiman, Sama F., Kumar, Amit, Brand, David, Smirnova, Natalya, Gazaryan, Irina, Khim, Soah J., Ratan, Rajiv R.

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Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative dise... von Gibson, Gary E., Starkov, Anatoly, Blass, John P., Ratan, Rajiv R., Beal, M. Flint

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Translational Control of Inducible Nitric Oxide Synthase Expression by Arginine Can Explain the Arginine Paradox von Lee, Junghee, Ryu, Hoon, Ferrante, Robert J., Morris, Sidney M., Ratan, Rajiv R.

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Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons von Brochier, Camille, Dennis, Gretel, Rivieccio, Mark A, McLaughlin, Kathryn, Coppola, Giovanni, Ratan, Rajiv R, Langley, Brett

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HDAC6 is a target for protection and regeneration following injury in the nervous system von Rivieccio, Mark A, Brochier, Camille, Willis, Dianna E, Walker, Breset A, D'Annibale, Melissa A, McLaughlin, Kathryn, Siddiq, Ambreena, Kozikowski, Alan P, Jaffrey, Samie R, Twiss, Jeffery L, Ratan, Rajiv R, Langley, Brett

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Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabe... von Chen, Y., Wang, J. J., Li, J., Hosoya, K. I., Ratan, R., Townes, T., Zhang, S. X.

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Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis von Neitemeier, S, Dolga, A M, Honrath, B, Karuppagounder, S S, Alim, I, Ratan, R R, Culmsee, C

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