The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients von McDonald, K.L, Rapkins, R.W, Olivier, J, Zhao, L, Nozue, K, Lu, D, Tiwari, S, Kuroiwa-Trzmielina, J, Brewer, J, Wheeler, H.R, Hitchins, M.P

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EG-11 DYSREGULATION OF MGMT IN GLIOBLASTOMA: FRIEND OR FOE? von Rapkins, R. W., Hitchins, M. P., McDonald, K. L.

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P08.22 Targeting glioblastoma mitochondrial metabolism to inhibit cell proliferation & tumor growth von Jue, T. J., Chung, S. A., Rapkins, R. W., Dilda, P., Hogg, P., McDonald, K. L.

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Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry von Ward, Robyn L., Dobbins, Timothy, Lindor, Noralane M., Rapkins, Robert W., Hitchins, Megan P.

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The role of TP53 gain-of-function mutation in multifocal glioblastoma von Olafson, Lauren R., Gunawardena, Manuri, Nixdorf, Sheri, McDonald, Kerrie L., Rapkins, Robert W.

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Construction and evolution of imprinted loci in mammals von Hore, Timothy A, Rapkins, Robert W, Graves, Jennifer A. Marshall

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Characterizing the chromosomes of the Australian model marsupial Macropus eugenii (tammar wallaby) von Alsop, Amber E, Miethke, Pat, Rofe, Ruth, Koina, Edda, Sankovic, Natasha, Deakin, Janine E, Haines, Helen, Rapkins, Robert W, Marshall Graves, Jennifer A

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Quality of Life in Clinical Medicine von Wyrwich, Kathleen W., Gross, Cynthia R.

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Intravitreal Triamcinolone Acetonide Inhibits Breakdown of the Blood-Retinal Barrier Through Differential Regulation of VEGF-A and Its Receptors in Early Diabetic Rat Retinas von XINYUAN ZHANG, SHISAN BAO, DONNA LAI, RAPKINS, Robert W, GILLIES, Mark C

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Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial von Olafson, Lauren R., Siddell, Anna H., Field, Kathryn M., Byrnes, Madeleine, Rapkins, Robert W., Ng, Benedict, Nixdorf, Sheri, Barnes, Elizabeth H., Johns, Terrance G., Yip, Sonia, Simes, John, Nowak, Anna K., Rosenthal, Mark A., McDonald, Kerrie L.

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The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype von Kwok, Chau-To, Vogelaar, Ingrid P, van Zelst-Stams, Wendy A, Mensenkamp, Arjen R, Ligtenberg, Marjolijn J, Rapkins, Robert W, Ward, Robyn L, Chun, Nicolette, Ford, James M, Ladabaum, Uri, McKinnon, Wendy C, Greenblatt, Marc S, Hitchins, Megan P

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P11.21.A LONG-TERM SURVIVAL WITH IDH WILDTYPE GLIOBLASTOMA: FIRST RESULTS FROM THE ETERNITY BRAIN TUMOR FUNDERS’ COLLABORATIVE CONSORTIUM (EORTC 1419) von Weller, M, Felsberg, J, Gramatzki, D, Le Rhun, E, Clarke, J, Soffietti, R, Wick, W, Chinot, O, Ducray, F, Roth, P, McDonald, K, Hau, P, Hottinger, A F, Reijneveld, J, Schnell, O, Marosi, C, Glantz, M, Darlix, A, Lombardi, G, Krex, D, Glas, M, Reardon, D A, van den Bent, M J, Lefranc, F, Herrlinger, U, Razis, E, Carpentier, A F, Phillips, S, Rudà, R, Wick, A, Tabouret, E, Meyronet, D, Maurage, C, Rushing, E, Rapkins, R

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The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide von Rapkins, Robert W, Wang, Fan, Nguyen, HuyTram N, Cloughesy, Timothy F, Lai, Albert, Ha, Wendy, Nowak, Anna K, Hitchins, Megan P, McDonald, Kerrie L

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Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma von Jue, Toni Rose, Nozue, Kyoko, Lester, Ashleigh J, Joshi, Swapna, Schroder, Lisette B W, Whittaker, Shane P, Nixdorf, Sheri, Rapkins, Robert W, Khasraw, Mustafa, McDonald, Kerrie L

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Recent assembly of an imprinted domain from non-imprinted components von Rapkins, Robert W, Hore, Tim, Smithwick, Megan, Ager, Eleanor, Pask, Andrew J, Renfree, Marilyn B, Kohn, Matthias, Hameister, Horst, Nicholls, Robert D, Deakin, Janine E, Graves, Jennifer A Marshall

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Understanding global transition assessments von Wyrwich, Kathleen W., Tardino, Vicki M.

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Representation and Governance in International Organizations von Rapkin, David P, Strand, Jonathan R, Trevathan, Michael W

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Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight von Werner, Bonnita, Yuwono, Nicole Laurencia, Henry, Claire, Gunther, Kate, Rapkins, Robert William, Ford, Caroline Elizabeth, Warton, Kristina

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Combining PARP inhibitors with radiation therapy for the treatment of glioblastoma: Is PTEN predictive of response? von Lester, A., Rapkins, R., Nixdorf, S., Khasraw, M., McDonald, K.

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A case study of a long-term glioblastoma survivor with unmethylated MGMT and hypermutated genotype von Jue, Toni Rose, Olafson, Lauren R, Siddell, Anna H, Rapkins, Robert W, Ng, Benedict, Yin, Julia X M, Lu, Victor M, Chung, Sylvia A, Whittaker, Shane P, Davies, Matthew, Fairhall, Jacob M, Hovey, Elizabeth J, McDonald, Kerrie L

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