Structural biology of SARS-CoV-2 and implications for therapeutic development von Yang, Haitao, Rao, Zihe

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Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur von Jin, Zhenming, Zhao, Yao, Sun, Yuan, Zhang, Bing, Wang, Haofeng, Wu, Yan, Zhu, Yan, Zhu, Chen, Hu, Tianyu, Du, Xiaoyu, Duan, Yinkai, Yu, Jing, Yang, Xiaobao, Yang, Xiuna, Yang, Kailin, Liu, Xiang, Guddat, Luke W., Xiao, Gengfu, Zhang, Leike, Yang, Haitao, Rao, Zihe

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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives von Amporndanai, Kangsa, Meng, Xiaoli, Shang, Weijuan, Jin, Zhenmig, Rogers, Michael, Zhao, Yao, Rao, Zihe, Liu, Zhi-Jie, Yang, Haitao, Zhang, Leike, O’Neill, Paul M., Samar Hasnain, S.

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Architecture of African swine fever virus and implications for viral assembly von Wang, Nan, Zhao, Dongming, Wang, Jialing, Zhang, Yangling, Wang, Ming, Gao, Yan, Li, Fang, Wang, Jingfei, Bu, Zhigao, Rao, Zihe, Wang, Xiangxi

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Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex von Ma, Yuanyuan, Wu, Lijie, Shaw, Neil, Gao, Yan, Wang, Jin, Sun, Yuna, Lou, Zhiyong, Yan, Liming, Zhang, Rongguang, Rao, Zihe

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Structure of the RNA-dependent RNA polymerase from COVID-19 virus von Gao, Yan, Yan, Liming, Huang, Yucen, Liu, Fengjiang, Zhao, Yao, Cao, Lin, Wang, Tao, Sun, Qianqian, Ming, Zhenhua, Zhang, Lianqi, Ge, Ji, Zheng, Litao, Zhang, Ying, Wang, Haofeng, Zhu, Yan, Zhu, Chen, Hu, Tianyu, Hua, Tian, Zhang, Bing, Yang, Xiuna, Li, Jun, Yang, Haitao, Liu, Zhijie, Xu, Wenqing, Guddat, Luke W, Wang, Quan, Lou, Zhiyong, Rao, Zihe

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Cryo-EM structure of a herpesvirus capsid at 3.1 Å von Yuan, Shuai, Wang, Jialing, Zhu, Dongjie, Wang, Nan, Gao, Qiang, Chen, Wenyuan, Tang, Hao, Wang, Junzhi, Zhang, Xinzheng, Liu, Hongrong, Rao, Zihe, Wang, Xiangxi

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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease von Dai, Wenhao, Zhang, Bing, Jiang, Xia-Ming, Su, Haixia, Li, Jian, Zhao, Yao, Xie, Xiong, Jin, Zhenming, Peng, Jingjing, Liu, Fengjiang, Li, Chunpu, Li, You, Bai, Fang, Wang, Haofeng, Cheng, Xi, Cen, Xiaobo, Hu, Shulei, Yang, Xiuna, Wang, Jiang, Liu, Xiang, Xiao, Gengfu, Jiang, Hualiang, Rao, Zihe, Zhang, Lei-Ke, Xu, Yechun, Yang, Haitao, Liu, Hong

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Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase von Wang, Quan, Wu, Jiqin, Wang, Haofeng, Gao, Yan, Liu, Qiaojie, Mu, An, Ji, Wenxin, Yan, Liming, Zhu, Yan, Zhu, Chen, Fang, Xiang, Yang, Xiaobao, Huang, Yucen, Gao, Hailong, Liu, Fengjiang, Ge, Ji, Sun, Qianqian, Yang, Xiuna, Xu, Wenqing, Liu, Zhijie, Yang, Haitao, Lou, Zhiyong, Jiang, Biao, Guddat, Luke W., Gong, Peng, Rao, Zihe

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Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody von Lv, Zhe, Deng, Yong-Qiang, Ye, Qing, Cao, Lei, Sun, Chun-Yun, Fan, Changfa, Huang, Weijin, Sun, Shihui, Sun, Yao, Zhu, Ling, Chen, Qi, Wang, Nan, Nie, Jianhui, Cui, Zhen, Zhu, Dandan, Shaw, Neil, Li, Xiao-Feng, Li, Qianqian, Xie, Liangzhi, Wang, Youchun, Rao, Zihe, Qin, Cheng-Feng, Wang, Xiangxi

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Structural and Biochemical Characterization of Endoribonuclease Nsp15 Encoded by Middle East Respiratory Syndrome Coronavirus von Zhang, Lianqi, Li, Lei, Yan, Liming, Ming, Zhenhua, Jia, Zhihui, Lou, Zhiyong, Rao, Zihe

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Architecture of a SARS-CoV-2 mini replication and transcription complex von Yan, Liming, Zhang, Ying, Ge, Ji, Zheng, Litao, Gao, Yan, Wang, Tao, Jia, Zhihui, Wang, Haofeng, Huang, Yucen, Li, Mingyu, Wang, Quan, Rao, Zihe, Lou, Zhiyong

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An electron transfer path connects subunits of a mycobacterial respiratory supercomplex von Gong, Hongri, Li, Jun, Xu, Ao, Tang, Yanting, Ji, Wenxin, Gao, Ruogu, Wang, Shuhui, Yu, Lu, Tian, Changlin, Li, Jingwen, Yen, Hsin-Yung, Man Lam, Sin, Shui, Guanghou, Yang, Xiuna, Sun, Yuna, Li, Xuemei, Jia, Minze, Yang, Cheng, Jiang, Biao, Lou, Zhiyong, Robinson, Carol V, Wong, Luet-Lok, Guddat, Luke W, Sun, Fei, Wang, Quan, Rao, Zihe

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High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors von Zhao, Yao, Du, Xiaoyu, Duan, Yinkai, Pan, Xiaoyan, Sun, Yifang, You, Tian, Han, Lin, Jin, Zhenming, Shang, Weijuan, Yu, Jing, Guo, Hangtian, Liu, Qianying, Wu, Yan, Peng, Chao, Wang, Jun, Zhu, Chenghao, Yang, Xiuna, Yang, Kailin, Lei, Ying, Guddat, Luke W., Xu, Wenqing, Xiao, Gengfu, Sun, Lei, Zhang, Leike, Rao, Zihe, Yang, Haitao

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A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes von Guo, Yu, Huang, Lisu, Zhang, Guangshun, Yao, Yanfeng, Zhou, He, Shen, Shu, Shen, Bingqing, Li, Bo, Li, Xin, Zhang, Qian, Chen, Mingjie, Chen, Da, Wu, Jia, Fu, Dan, Zeng, Xinxin, Feng, Mingfang, Pi, Chunjiang, Wang, Yuan, Zhou, Xingdong, Lu, Minmin, Li, Yarong, Fang, Yaohui, Lu, Yun-Yueh, Hu, Xue, Wang, Shanshan, Zhang, Wanju, Gao, Ge, Adrian, Francisco, Wang, Qisheng, Yu, Feng, Peng, Yun, Gabibov, Alexander G., Min, Juan, Wang, Yuhui, Huang, Heyu, Stepanov, Alexey, Zhang, Wei, Cai, Yan, Liu, Junwei, Yuan, Zhiming, Zhang, Chen, Lou, Zhiyong, Deng, Fei, Zhang, Hongkai, Shan, Chao, Schweizer, Liang, Sun, Kun, Rao, Zihe

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Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target von Zhang, Bing, Li, Jun, Yang, Xiaolin, Wu, Lijie, Zhang, Jia, Yang, Yang, Zhao, Yao, Zhang, Lu, Yang, Xiuna, Yang, Xiaobao, Cheng, Xi, Liu, Zhijie, Jiang, Biao, Jiang, Hualiang, Guddat, Luke W., Yang, Haitao, Rao, Zihe

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Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2 von Zhao, Yao, Zhu, Yan, Liu, Xiang, Jin, Zhenming, Duan, Yinkai, Zhang, Qi, Wu, Chengyao, Feng, Lu, Du, Xiaoyu, Zhao, Jinyi, Shao, Maolin, Zhang, Bing, Yang, Xiuna, Wu, Lijie, Ji, Xiaoyun, Guddat, Luke W, Yang, Kailin, Rao, Zihe, Yang, Haitao

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Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels von Wang, Weiwei, Gao, Yan, Tang, Yanting, Zhou, Xiaoting, Lai, Yuezheng, Zhou, Shan, Zhang, Yuying, Yang, Xiuna, Liu, Fengjiang, Guddat, Luke W., Wang, Quan, Rao, Zihe, Gong, Hongri

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Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage von Wang, Kang, Zhu, Ling, Sun, Yao, Li, Minhao, Zhao, Xin, Cui, Lunbiao, Zhang, Li, Gao, George F., Zhai, Weiwei, Zhu, Fengcai, Rao, Zihe, Wang, Xiangxi

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Structural basis for recognition and regulation of arenavirus polymerase L by Z protein von Kang, Huiling, Cong, Jingyuan, Wang, Chenlong, Ji, Wenxin, Xin, Yuhui, Qian, Ying, Li, Xuemei, Chen, Yutao, Rao, Zihe

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