Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression von Valet, Colin, Magnen, Mélia, Qiu, Longhui, Cleary, Simon J, Wang, Kristin M, Ranucci, Serena, Grockowiak, Elodie, Boudra, Rafik, Conrad, Catharina, Seo, Yurim, Calabrese, Daniel R, Greenland, John R, Leavitt, Andrew D, Passegué, Emmanuelle, Méndez-Ferrer, Simón, Swirski, Filip K, Looney, Mark R

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Pseudomonas aeruginosa Elastase Contributes to the Establishment of Chronic Lung Colonization and Modulates the Immune Response in a Murine Model von Cigana, Cristina, Castandet, Jérôme, Sprynski, Nicolas, Melessike, Medede, Beyria, Lilha, Ranucci, Serena, Alcalá-Franco, Beatriz, Rossi, Alice, Bragonzi, Alessandra, Zalacain, Magdalena, Everett, Martin

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The Small RNA ErsA Plays a Role in the Regulatory Network of Pseudomonas aeruginosa Pathogenicity in Airway Infections von Ferrara, Silvia, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Bragonzi, Alessandra, Cigana, Cristina, Bertoni, Giovanni

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Type-4 Phosphodiesterase (PDE4) Blockade Reduces NETosis in Cystic Fibrosis von Totani, Licia, Amore, Concetta, Piccoli, Antonio, Dell’Elba, Giuseppe, Di Santo, Angelo, Plebani, Roberto, Pecce, Romina, Martelli, Nicola, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Moretti, Paolo, Bragonzi, Alessandra, Romano, Mario, Evangelista, Virgilio

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Liposomes Loaded With Phosphatidylinositol 5-Phosphate Improve the Antimicrobial Response to Pseudomonas aeruginosa in Impaired Macrophages From Cystic Fibrosis Patients and Limit... von Poerio, Noemi, De Santis, Federica, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Henriquez, Ana, D'Andrea, Marco M, Ciciriello, Fabiana, Lucidi, Vincenzina, Nisini, Roberto, Bragonzi, Alessandra, Fraziano, Maurizio

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In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa von Fernández-Piñar, Regina, Lo Sciuto, Alessandra, Rossi, Alice, Ranucci, Serena, Bragonzi, Alessandra, Imperi, Francesco

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810 NX-1607, a small molecule inhibitor of CBL-B, enhances anti-PD-1-mediated tumor growth inhibition by reshaping intratumoral innate and adaptive immune response von Gallotta, Marilena, Romo, Jose Gomez, Ranucci, Serena, Lee, Ernestine, Borodovsky, Alexandra, Hansen, Gwenn M, Sands, Arthur T, Rountree, Ryan, Guiducci, Cristiana

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The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy von Inverso, Donato, Tacconi, Carlotta, Ranucci, Serena, De Giovanni, Marco

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Antibiotic efficacy varies based on the infection model and treatment regimen for Pseudomonas aeruginosa von Cigana, Cristina, Ranucci, Serena, Rossi, Alice, De Fino, Ida, Melessike, Medede, Bragonzi, Alessandra

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Aerosolized Bovine Lactoferrin Counteracts Infection, Inflammation and Iron Dysbalance in A Cystic Fibrosis Mouse Model of Pseudomonas aeruginosa Chronic Lung Infection von Cutone, Antimo, Lepanto, Maria Stefania, Rosa, Luigi, Scotti, Mellani Jinnett, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Bragonzi, Alessandra, Valenti, Piera, Musci, Giovanni, Berlutti, Francesca

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Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes von Chen, Kevin Y., De Giovanni, Marco, Xu, Ying, An, Jinping, Kirthivasan, Nikhita, Lu, Erick, Jiang, Kan, Brooks, Stephen, Ranucci, Serena, Yang, Jiuling, Kanameishi, Shuto, Kabashima, Kenji, Brulois, Kevin, Bscheider, Michael, Butcher, Eugene C., Cyster, Jason G.

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Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation von Ortiz-Muñoz, Guadalupe, Yu, Michelle A, Lefrançais, Emma, Mallavia, Beñat, Valet, Colin, Tian, Jennifer J, Ranucci, Serena, Wang, Kristin M, Liu, Zhe, Kwaan, Nicholas, Dawson, Diana, Kleinhenz, Mary Ellen, Khasawneh, Fadi T, Haggie, Peter M, Verkman, Alan S, Looney, Mark R

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Therapeutic potential of co-signaling receptor modulation in hepatitis B von Andreata, Francesco, Laura, Chiara, Ravà, Micol, Krueger, Caroline C., Ficht, Xenia, Kawashima, Keigo, Beccaria, Cristian G., Moalli, Federica, Partini, Bianca, Fumagalli, Valeria, Nosetto, Giulia, Di Lucia, Pietro, Montali, Ilaria, Garcia-Manteiga, José M., Bono, Elisa B., Giustini, Leonardo, Perucchini, Chiara, Venzin, Valentina, Ranucci, Serena, Inverso, Donato, De Giovanni, Marco, Genua, Marco, Ostuni, Renato, Lugli, Enrico, Isogawa, Masanori, Ferrari, Carlo, Boni, Carolina, Fisicaro, Paola, Guidotti, Luca G., Iannacone, Matteo

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Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lu... von De Fenza, Maria, D'Alonzo, Daniele, Esposito, Anna, Munari, Silvia, Loberto, Nicoletta, Santangelo, Alessandra, Lampronti, Ilaria, Tamanini, Anna, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Bragonzi, Alessandra, Aureli, Massimo, Bassi, Rosaria, Tironi, Matteo, Lippi, Giuseppe, Gambari, Roberto, Cabrini, Giulio, Palumbo, Giovanni, Dechecchi, Maria Cristina, Guaragna, Annalisa

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Efficacy of the Novel Antibiotic POL7001 in Preclinical Models of Pseudomonas aeruginosa Pneumonia von Cigana, Cristina, Bernardini, Francesca, Facchini, Marcella, Alcalá-Franco, Beatriz, Riva, Camilla, De Fino, Ida, Rossi, Alice, Ranucci, Serena, Misson, Pauline, Chevalier, Eric, Brodmann, Maj, Schmitt, Michel, Wach, Achim, Dale, Glenn E, Obrecht, Daniel, Bragonzi, Alessandra

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Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis von Rimessi, Alessandro, Pozzato, Chiara, Carparelli, Lorenzo, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Cigana, Cristina, Talarico, Anna, Wieckowski, Mariusz R, Ribeiro, Carla M P, Trapella, Claudio, Rossi, Giacomo, Cabrini, Giulio, Bragonzi, Alessandra, Pinton, Paolo

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Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response von Farinelli, Giada, Jofra Hernandez, Raisa, Rossi, Alice, Ranucci, Serena, Sanvito, Francesca, Migliavacca, Maddalena, Brombin, Chiara, Pramov, Aleksandar, Di Serio, Clelia, Bovolenta, Chiara, Gentner, Bernhard, Bragonzi, Alessandra, Aiuti, Alessandro

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226. Lentiviral Vector Gene Therapy Protects XCGD Mice from Acute Staphylococcus aureus Pneumonia and Inflammatory Response von Farinelli, Giada, Hernandez, Raisa Jofra, Rossi, Alice, Ranucci, Serena, Sanvito, Francesca, Migliavacca, Maddalena, Brombin, Chiara, Pramov, Aleksandar, Di Serio, Clelia, Gentner, Bernhard, Bragonzi, Alessandra, Aiuti, Alessandro

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288. Dual-Regulated Lentiviral Vector for Gene Therapy of X-Linked Chronic Granulomatous Disease von Farinelli, Giada, Chiriaco, Maria, Capo, Valentina, Zonari, Erika, Migliavacca, Maddalena, Jofra Hernandez, Raisa, Scaramuzza, Samantha, Di Matteo, Gigliola, Sergi Sergi, Lucia, Rossi, Alice, Ranucci, Serena, Bragonzi, Alessandra, Kajaste-Rudnitski, Anna, Trono, Didier, Grez, Manuel, Rossi, Paolo, Finocchi, Andrea, Naldini, Luigi, Gentner, Bernhard, Aiuti, Alessandro

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Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression von Valet, Colin, Magnen, Mélia, Qiu, Longhui, Cleary, Simon J, Wang, Kristin M, Ranucci, Serena, Grockowiak, Elodie, Boudra, Rafik, Conrad, Catharina, Seo, Yurim, Calabrese, Daniel R, Greenland, John R, Leavitt, Andrew D, Passegué, Emmanuelle, Méndez-Ferrer, Simón, Swirski, Filip K, Looney, Mark R

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