CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure von Rankovic, Zoran

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CNS Physicochemical Property Space Shaped by a Diverse Set of Molecules with Experimentally Determined Exposure in the Mouse Brain von Rankovic, Zoran

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Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs von Min, Jaeki, Mayasundari, Anand, Keramatnia, Fatemeh, Jonchere, Barbara, Yang, Seung Wook, Jarusiewicz, Jamie, Actis, Marisa, Das, Sourav, Young, Brandon, Slavish, Jake, Yang, Lei, Li, Yong, Fu, Xiang, Garrett, Shalandus H., Yun, Mi‐Kyung, Li, Zhenmei, Nithianantham, Stanley, Chai, Sergio, Chen, Taosheng, Shelat, Anang, Lee, Richard E., Nishiguchi, Gisele, White, Stephen W., Roussel, Martine F., Potts, Patrick Ryan, Fischer, Marcus, Rankovic, Zoran

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Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases von Yang, Seung Wook, Huang, Xin, Lin, Wenwei, Min, Jaeki, Miller, Darcie J., Mayasundari, Anand, Rodrigues, Patrick, Griffith, Elizabeth C., Gee, Clifford T., Li, Lei, Li, Wei, Lee, Richard E., Rankovic, Zoran, Chen, Taosheng, Potts, Patrick Ryan

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Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia von Chang, Yunchao, Min, Jaeki, Jarusiewicz, Jamie A., Actis, Marisa, Yu-Chen Bradford, Shanshan, Mayasundari, Anand, Yang, Lei, Chepyala, Divyabharathi, Alcock, Lisa J., Roberts, Kathryn G., Nithianantham, Stanley, Maxwell, Dylan, Rowland, Lauren, Larsen, Randolph, Seth, Aman, Goto, Hiroaki, Imamura, Toshihiko, Akahane, Koshi, Hansen, Baranda S., Pruett-Miller, Shondra M., Paietta, Elisabeth M., Litzow, Mark R., Qu, Chunxu, Yang, Jun J., Fischer, Marcus, Rankovic, Zoran, Mullighan, Charles G.

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Designed Multiple Ligands. An Emerging Drug Discovery Paradigm von Morphy, Richard, Rankovic, Zoran

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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma von He, Chen, Xu, Ke, Zhu, Xiaoyan, Dunphy, Paige S., Gudenas, Brian, Lin, Wenwei, Twarog, Nathaniel, Hover, Laura D., Kwon, Chang-Hyuk, Kasper, Lawryn H., Zhang, Junyuan, Li, Xiaoyu, Dalton, James, Jonchere, Barbara, Mercer, Kimberly S., Currier, Duane G., Caufield, William, Wang, Yingzhe, Xie, Jia, Broniscer, Alberto, Wetmore, Cynthia, Upadhyaya, Santhosh A., Qaddoumi, Ibrahim, Klimo, Paul, Boop, Frederick, Gajjar, Amar, Zhang, Jinghui, Orr, Brent A., Robinson, Giles W., Monje, Michelle, Freeman III, Burgess B., Roussel, Martine F., Northcott, Paul A., Chen, Taosheng, Rankovic, Zoran, Wu, Gang, Chiang, Jason, Tinkle, Christopher L., Shelat, Anang A., Baker, Suzanne J.

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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines von Nishiguchi, Gisele, Mascibroda, Lauren G., Young, Sarah M., Caine, Elizabeth A., Abdelhamed, Sherif, Kooijman, Jeffrey J., Miller, Darcie J., Das, Sourav, McGowan, Kevin, Mayasundari, Anand, Shi, Zhe, Barajas, Juan M., Hiltenbrand, Ryan, Aggarwal, Anup, Chang, Yunchao, Mishra, Vibhor, Narina, Shilpa, Thomas, Melvin, Loughran, Allister J., Kalathur, Ravi, Yu, Kaiwen, Zhou, Suiping, Wang, Xusheng, High, Anthony A., Peng, Junmin, Pruett-Miller, Shondra M., Daniels, Danette L., Urh, Marjeta, Shelat, Anang A., Mullighan, Charles G., Riching, Kristin M., Zaman, Guido J. R., Fischer, Marcus, Klco, Jeffery M., Rankovic, Zoran

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Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia von Park, Chun Shik, Yoshihara, Hiroki, Gao, Qingsong, Qu, Chunxu, Iacobucci, Ilaria, Ghate, Pankaj S., Connelly, Jon P., Pruett-Miller, Shondra M., Wagner, Ben, Robinson, Camenzind G., Mishra, Ashutosh, Peng, Junmin, Yang, Lei, Rankovic, Zoran, Finkelstein, David, Luger, Selina, Litzow, Mark, Paietta, Elisabeth M., Hebbar, Nikhil, Velasquez, M. Paulina, Mullighan, Charles G.

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Retraction of “CNS Physicochemical Property Space Shaped by a Diverse Set of Molecules with Experimentally Determined Exposure in the Mouse Brain” von Rankovic, Zoran

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Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy von Zuckermann, Marc, He, Chen, Andrews, Jared, Bagchi, Aditi, Sloan-Henry, Roketa, Bianski, Brandon, Xie, Jia, Wang, Yingzhe, Twarog, Nathaniel, Onar-Thomas, Arzu, Ernst, Kati J, Yang, Lei, Li, Yong, Zhu, Xiaoyan, Ocasio, Jennifer K, Budd, Kaitlin M, Dalton, James, Li, Xiaoyu, Chepyala, Divyabharathi, Zhang, Junyuan, Xu, Ke, Hover, Laura, Roach, Jordan T, Chan, Kenneth Chun-Ho, Hofmann, Nina, McKinnon, Peter J, Pfister, Stefan M, Shelat, Anang A, Rankovic, Zoran, Freeman, 3rd, Burgess B, Chiang, Jason, Jones, David T W, Tinkle, Christopher L, Baker, Suzanne J

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Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents von Ling, Taotao, Maier, Julie, Das, Sourav, Budhraja, Amit, Bassett, Rachel, Potts, Malia B., Shelat, Anang, Rankovic, Zoran, Opferman, Joseph T., Rivas, Fatima

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A high-throughput quality control method for assessing the serial dilution performance of dose–response plates with acoustic ejection mass spectrometry von Rimmer, Mary Ashley, Twarog, Nathaniel R, Li, Yong, Shelat, Anang A, Rankovic, Zoran, Yang, Lei

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CNS Physicochemical Property Space Shaped by a Diverse Set of Molecules with Experimentally Determined Exposure in the Mouse Brain: Miniperspective von Rankovic, Zoran

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New pyridine N-oxides as chiral organocatalysts in the asymmetric allylation of aromatic aldehydes von Malkov, Andrei V., Westwater, Mary-Margaret, Gutnov, Andrey, Ramírez-López, Pedro, Friscourt, Frédéric, Kadlčíková, Aneta, Hodačová, Jana, Rankovic, Zoran, Kotora, Martin, Kočovský, Pavel

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The Physicochemical Challenges of Designing Multiple Ligands von Morphy, Richard, Rankovic, Zoran

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Small molecule SJ572946 activates BAK to initiate apoptosis von Sekar, Giridhar, Singh, Geetika, Qin, Xingping, Guibao, Cristina D., Schwam, Brittany, Inde, Zintis, Grace, Christy R., Zhang, Weixing, Slavish, P. Jake, Lin, Wenwei, Chen, Taosheng, Lee, Richard E., Rankovic, Zoran, Sarosiek, Kristopher, Moldoveanu, Tudor

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A protocol for high-throughput screening of histone lysine demethylase 4 inhibitors using TR-FRET assay von Wu, Qiong, Lin, Wenwei, Li, Zhen-Mei, Rankovic, Zoran, White, Stephen W., Chen, Taosheng, Yang, Jun

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A one-pot procedure for methylenating carbonyl compounds using the Nysted reagent and titanocene dichloride von Haahr, Adam, Rankovic, Zoran, Hartley, Richard C.

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17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma von Singh, Shivendra, Abu-Zaid, Ahmed, Lin, Wenwei, Low, Jonathan, Abdolvahabi, Alireza, Jin, Hongjian, Wu, Qiong, Cooke, Bailey, Fang, Jie, Bowling, John, Vaithiyalingam, Sivaraja, Currier, Duane, Yun, Mi-Kyung, Fernando, Dinesh M., Maier, Julie, Tillman, Heather, Bulsara, Purva, Lu, Zhaohua, Das, Sourav, Shelat, Anang, Li, Zhenmei, Young, Brandon, Lee, Richard, Rankovic, Zoran, Murphy, Andrew J., White, Stephen W., Davidoff, Andrew M., Chen, Taosheng, Yang, Jun

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