A critical re-evaluation of the slope factor of the operational model of agonism: When to exponentiate operational efficacy von Randáková, Alena, Nelic, Dominik, Jakubík, Jan

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The operational model of allosteric modulation of pharmacological agonism von Jakubík, Jan, Randáková, Alena, Chetverikov, Nikolai, El-Fakahany, Esam E., Doležal, Vladimír

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Agonist-selective activation of individual G-proteins by muscarinic receptors von Nelic, Dominik, Chetverikov, Nikolai, Hochmalová, Martina, Diaz, Christina, Doležal, Vladimír, Boulos, John, Jakubík, Jan, Martemyanov, Kirill, Janoušková-Randáková, Alena

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Agonist-Specific Conformations of the M2 Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics von Randáková, Alena, Nelic, Dominik, Doležal, Vladimír, El-Fakahany, Esam E, Boulos, John, Jakubík, Jan

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Functionally selective and biased agonists of muscarinic receptors von Randáková, Alena, Jakubík, Jan

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Applications and limitations of fitting of the operational model to determine relative efficacies of agonists von Jakubík, Jan, Randáková, Alena, Rudajev, Vladimír, Zimčík, Pavel, El-Fakahany, Esam E., Doležal, Vladimír

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Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids von Szczurowska, Ewa, Szánti-Pintér, Eszter, Randáková, Alena, Jakubík, Jan, Kudova, Eva

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Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators von Dolezal, Vladimír, Jakubík, Jan, El-Fakahany, Esam E, Randáková, Alena

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Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids von Szczurowska, Ewa, Szánti-Pintér, Eszter, Chetverikov, Nikolai, Randáková, Alena, Kudová, Eva, Jakubík, Jan

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Neurosteroids and steroid hormones are allosteric modulators of muscarinic receptors von Dolejší, Eva, Szánti-Pintér, Eszter, Chetverikov, Nikolai, Nelic, Dominik, Randáková, Alena, Doležal, Vladimír, Kudová, Eva, Jakubík, Jan

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Agonist-Specific Conformations of the M 2 Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics von Randáková, Alena, Nelic, Dominik, Doležal, Vladimír, El-Fakahany, Esam E, Boulos, John, Jakubík, Jan

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Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors von Dolejší, Eva, Chetverikov, Nikolai, Szánti-Pintér, Eszter, Nelic, Dominik, Randáková, Alena, Doležal, Vladimír, El-Fakahany, Esam E., Kudová, Eva, Jakubík, Jan

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Novel long‐acting antagonists of muscarinic ACh receptors von Randáková, Alena, Rudajev, Vladimír, Doležal, Vladimír, Boulos, John, Jakubík, Jan

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Novel M2‐selective, Gi‐biased agonists of muscarinic acetylcholine receptors von Randáková, Alena, Nelic, Dominik, Ungerová, Dana, Nwokoye, Peter, Su, Qiwen, Doležal, Vladimír, El‐Fakahany, Esam E., Boulos, John, Jakubík, Jan

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Role of membrane cholesterol in differential sensitivity of muscarinic receptor subtypes to persistently bound xanomeline von Randáková, Alena, Dolejší, Eva, Rudajev, Vladimír, Zimčík, Pavel, Doležal, Vladimír, El-Fakahany, Esam E., Jakubík, Jan

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Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors von Jakubík, Jan, Randáková, Alena, Zimčík, Pavel, El-Fakahany, Esam E., Doležal, Vladimír

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Molecular Mechanisms of Methoctramine Binding and Selectivity at Muscarinic Acetylcholine Receptors von Jakubík, Jan, Zimčík, Pavel, Randáková, Alena, Fuksová, Květoslava, El-Fakahany, Esam E., Doležal, Vladimír

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Fusion with Promiscuous Gα16 Subunit Reveals Signaling Bias at Muscarinic Receptors von Randáková, Alena, Nelic, Dominik, Hochmalová, Martina, Zimčík, Pavel, Mulenga, Mutale Jane, Boulos, John, Jakubík, Jan

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On homology modeling of the M2 muscarinic acetylcholine receptor subtype von Jakubík, Jan, Randáková, Alena, Doležal, Vladimír

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Subtype differences in pre-coupling of muscarinic acetylcholine receptors von Dolezal, Vladimír, Jakubík, Jan, El-Fakahany, Esam E, Janícková, Helena, Randáková, Alena

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