Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA von Nishimasu, Hiroshi, Ran, F. Ann, Hsu, Patrick D., Konermann, Silvana, Shehata, Soraya I., Dohmae, Naoshi, Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu

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Crystal Structure of Staphylococcus aureus Cas9 von Nishimasu, Hiroshi, Cong, Le, Yan, Winston X., Ran, F. Ann, Zetsche, Bernd, Li, Yinqing, Kurabayashi, Arisa, Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu

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Multiplex Genome Engineering Using CRISPR/Cas Systems von Cong, Le, Ran, F. Ann, Cox, David, Lin, Shuailiang, Barretto, Robert, Habib, Naomi, Hsu, Patrick D., Wu, Xuebing, Jiang, Wenyan, Marraffini, Luciano A., Zhang, Feng

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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy von Nelson, Christopher E., Hakim, Chady H., Ousterout, David G., Thakore, Pratiksha I., Moreb, Eirik A., Rivera, Ruth M. Castellanos, Madhavan, Sarina, Pan, Xiufang, Ran, F. Ann, Yan, Winston X., Asokan, Aravind, Zhang, Feng, Duan, Dongsheng, Gersbach, Charles A.

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In vivo gene editing in dystrophic mouse muscle and muscle stem cells von Tabebordbar, Mohammadsharif, Zhu, Kexian, Cheng, Jason K. W., Chew, Wei Leong, Widrick, Jeffrey J., Yan, Winston X., Maesner, Claire, Wu, Elizabeth Y., Xiao, Ru, Ran, F. Ann, Le Cong, Zhang, Feng, Vandenberghe, Luk H., Church, George M., Wagers, Amy J.

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DNA targeting specificity of RNA-guided Cas9 nucleases von Hsu, Patrick D, Scott, David A, Weinstein, Joshua A, Ran, F Ann, Konermann, Silvana, Agarwala, Vineeta, Li, Yinqing, Fine, Eli J, Wu, Xuebing, Shalem, Ophir, Cradick, Thomas J, Marraffini, Luciano A, Bao, Gang, Zhang, Feng

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Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems von Yamada, Mari, Watanabe, Yuto, Gootenberg, Jonathan S., Hirano, Hisato, Ran, F. Ann, Nakane, Takanori, Ishitani, Ryuichiro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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RNA-responsive elements for eukaryotic translational control von Zhao, Evan M., Mao, Angelo S., de Puig, Helena, Zhang, Kehan, Tippens, Nathaniel D., Tan, Xiao, Ran, F. Ann, Han, Isaac, Nguyen, Peter Q., Chory, Emma J., Hua, Tiffany Y., Ramesh, Pradeep, Thompson, David B., Oh, Crystal Yuri, Zigon, Eric S., English, Max A., Collins, James J.

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Adaptation of CRISPR nucleases for eukaryotic applications von Ran, F. Ann

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Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells von Lee, Mark N., Ye, Chun, Villani, Alexandra-Chloé, Raj, Towfique, Li, Weibo, Eisenhaure, Thomas M., Imboywa, Selina H., Chipendo, Portia I., Ran, F. Ann, Slowikowski, Kamil, Ward, Lucas D., Raddassi, Khadir, McCabe, Cristin, Lee, Michelle H., Frohlich, Irene Y., Hafler, David A., Kellis, Manolis, Raychaudhuri, Soumya, Zhang, Feng, Stranger, Barbara E., Benoist, Christophe O., De Jager, Philip L., Regev, Aviv, Hacohen, Nir

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Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity von Ran, F. Ann, Hsu, Patrick D., Lin, Chie-Yu, Gootenberg, Jonathan S., Konermann, Silvana, Trevino, Alexandro E., Scott, David A., Inoue, Azusa, Matoba, Shogo, Zhang, Yi, Zhang, Feng

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Genome engineering using the CRISPR-Cas9 system von Ran, F Ann, Hsu, Patrick D, Wright, Jason, Agarwala, Vineeta, Scott, David A, Zhang, Feng

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Toripalimab (anti-PD-1) versus high-dose interferon-α2b as adjuvant therapy in resected mucosal melanoma: a phase II randomized trial von Lian, B., Si, L., Chi, Z.H., Sheng, X.N., Kong, Y., Wang, X., Tian, H., Li, K., Mao, L.L., Bai, X., Tang, B.X., Yan, X.Q., Li, S.M., Zhou, L., Dai, J., Tang, X.W., Ran, F.W., Yao, S., Guo, J., Cui, C.L.

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Epidermal Growth Factor Receptor Mutation Status and the Impact on Clinical Outcomes in Patients with Non-Small Cell Lung Cancer von Huang, HM, Wei, Y, Wang, JJ, Ran, FY, Wen, Y, Chen, QH, Zhang, BF

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In vivo genome editing using Staphylococcus aureus Cas9 von Ran, F. Ann, Cong, Le, Yan, Winston X., Scott, David A., Gootenberg, Jonathan S., Kriz, Andrea J., Zetsche, Bernd, Shalem, Ophir, Wu, Xuebing, Makarova, Kira S., Koonin, Eugene V., Sharp, Phillip A., Zhang, Feng

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Direct synthesis of heparin-like poly(ether sulfone) polymer and its blood compatibility von Wang, L.R., Qin, H., Nie, S.Q., Sun, S.D., Ran, F., Zhao, C.S.

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Ultralow-frequency Raman system down to 10 cm(-1) with longpass edge filters and its application to the interface coupling in t(2+2)LGs von Lin, M-L, Ran, F-R, Qiao, X-F, Wu, J-B, Shi, W, Zhang, Z-H, Xu, X-Z, Liu, K-H, Li, H, Tan, P-H

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Effect of fatty acid synthase gene silencing on lipid metabolism and biological behaviors of human hepatoblastoma HepG2 cells von Huang, H, Wei, Y, Wang, J, Ran, F, Chen, Q

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Jasmonic acid serves as a signal role in smoke-isolated butenolide-induced tanshinones biosynthesis in Salvia miltiorrhiza hairy root von Zhou, J., Ran, Z.-F., Liu, Q., Xu, Z.-X., Xiong, Y.-H., Fang, L., Guo, L.-P.

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Miniature Protein Inhibitors of the p53-hDM2 Interaction von Kritzer, Joshua A, Zutshi, Reena, Cheah, Mingtatt, Ran, F. Ann, Webman, Rachel, Wongjirad, Taritree M, Schepartz, Alanna

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