Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion von Freeman, Andrew J., Vervoort, Stephin J., Ramsbottom, Kelly M., Kelly, Madison J., Michie, Jessica, Pijpers, Lizzy, Johnstone, Ricky W., Kearney, Conor J., Oliaro, Jane

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PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF von Kearney, Conor J, Lalaoui, Najoua, Freeman, Andrew J, Ramsbottom, Kelly M, Silke, John, Oliaro, Jane

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Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time von Jenkins, Misty R, Rudd-Schmidt, Jesse A, Lopez, Jamie A, Ramsbottom, Kelly M, Mannering, Stuart I, Andrews, Daniel M, Voskoboinik, Ilia, Trapani, Joseph A

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HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis von Freeman, Andrew J, Vervoort, Stephin J, Michie, Jessica, Ramsbottom, Kelly M, Silke, John, Kearney, Conor J, Oliaro, Jane

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CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory von Lelliott, Emily J, Kong, Isabella Y, Zethoven, Magnus, Ramsbottom, Kelly M, Martelotto, Luciano G, Meyran, Deborah, Zhu, Joe Jiang, Costacurta, Matteo, Kirby, Laura, Sandow, Jarrod J, Lim, Lydia, Dominguez, Pilar M, Todorovski, Izabela, Haynes, Nicole M, Beavis, Paul A, Neeson, Paul J, Hawkins, Edwin D, McArthur, Grant A, Parish, Ian A, Johnstone, Ricky W, Oliaro, Jane, Sheppard, Karen E, Kearney, Conor J, Vervoort, Stephin J

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Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance von Wagle, Mayura V., Vervoort, Stephin J., Kelly, Madison J., Van Der Byl, Willem, Peters, Timothy J., Martin, Ben P., Martelotto, Luciano G., Nüssing, Simone, Ramsbottom, Kelly M., Torpy, James R., Knight, Deborah, Reading, Sinead, Thia, Kevin, Miosge, Lisa A., Howard, Debbie R., Gloury, Renee, Gabriel, Sarah S., Utzschneider, Daniel T., Oliaro, Jane, Powell, Jonathan D., Luciani, Fabio, Trapani, Joseph A., Johnstone, Ricky W., Kallies, Axel, Goodnow, Christopher C., Parish, Ian A.

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Intracellular zinc protects tumours from T cell-mediated cytotoxicity von Lelliott, Emily J., Naddaf, Jonathan, Ganio, Katherine, Michie, Jessica, Wang, Shelly, Liu, Lin, Silke, Natasha, Ahn, Antonio, Ramsbottom, Kelly M., Brennan, Amelia J., Freeman, Andrew J., Goel, Shom, Vervoort, Stephin J., Kearney, Conor J., Beavis, Paul A., McDevitt, Christopher A., Silke, John, Oliaro, Jane

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Antagonism of IAPs Enhances CAR T-cell Efficacy von Michie, Jessica, Beavis, Paul A, Freeman, Andrew J, Vervoort, Stephin J, Ramsbottom, Kelly M, Narasimhan, Vignesh, Lelliott, Emily J, Lalaoui, Najoua, Ramsay, Robert G, Johnstone, Ricky W, Silke, John, Darcy, Phillip K, Voskoboinik, Ilia, Kearney, Conor J, Oliaro, Jane

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NKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation von Lelliott, Emily J., Ramsbottom, Kelly M., Dowling, Mark R., Shembrey, Carolyn, Noori, Tahereh, Kearney, Conor J., Michie, Jessica, Parish, Ian A., Jordan, Margaret A., Baxter, Alan G., Young, Neil D., Brennan, Amelia J., Oliaro, Jane

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The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects von Van Der Byl, Willem, Nüssing, Simone, Peters, Timothy J., Ahn, Antonio, Li, Hanjie, Ledergor, Guy, David, Eyal, Koh, Andrew S., Wagle, Mayura V., Deguit, Christian Deo T., de Menezes, Maria N., Travers, Avraham, Sampurno, Shienny, Ramsbottom, Kelly M., Li, Rui, Kallies, Axel, Beavis, Paul A., Jungmann, Ralf, Bastings, Maartje M.C., Belz, Gabrielle T., Goel, Shom, Trapani, Joseph A., Crabtree, Gerald R., Chang, Howard Y., Amit, Ido, Goodnow, Chris C., Luciani, Fabio, Parish, Ian A.

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Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing von Kearney, Conor J., Ramsbottom, Kelly M., Voskoboinik, Ilia, Darcy, Phillip K., Oliaro, Jane

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SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells von Kearney, Conor J, Vervoort, Stephin J, Ramsbottom, Kelly M, Todorovski, Izabela, Lelliott, Emily J, Zethoven, Magnus, Pijpers, Lizzy, Martin, Ben P, Semple, Timothy, Martelotto, Luciano, Trapani, Joseph A, Parish, Ian A, Scott, Nichollas E, Oliaro, Jane, Johnstone, Ricky W

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Cutting edge: DNAX accessory molecule 1-deficient CD8+ T cells display immunological synapse defects that impair antitumor immunity von Ramsbottom, Kelly M, Hawkins, Edwin D, Shimoni, Raz, McGrath, Mairi, Chan, Christopher J, Russell, Sarah M, Smyth, Mark J, Oliaro, Jane

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HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2 + Tumors von Medon, Mikolaj, Vidacs, Eva, Vervoort, Stephin J, Li, Jason, Jenkins, Misty R, Ramsbottom, Kelly M, Trapani, Joseph A, Smyth, Mark J, Darcy, Phillip K, Atadja, Peter W, Henderson, Michael A, Johnstone, Ricky W, Haynes, Nicole M

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Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia von Hawkins, Edwin D, Oliaro, Jane, Ramsbottom, Kelly M, Ting, Stephen B, Sacirbegovic, Faruk, Harvey, Michael, Kinwell, Tanja, Ghysdael, Jacques, Johnstone, Ricky W, Humbert, Patrick O, Russell, Sarah M

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A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy von Lelliott, Emily J., Cullinane, Carleen, Martin, Claire A., Walker, Rachael, Ramsbottom, Kelly M., Souza-Fonseca-Guimaraes, Fernando, Abuhammad, Shatha, Michie, Jessica, Kirby, Laura, Young, Richard J., Slater, Alison, Lau, Peter, Meeth, Katrina, Oliaro, Jane, Haynes, Nicole, McArthur, Grant A., Sheppard, Karen E.

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DOCK8 Drives Src-Dependent NK Cell Effector Function von Kearney, Conor J, Vervoort, Stephin J, Ramsbottom, Kelly M, Freeman, Andrew J, Michie, Jessica, Peake, Jane, Casanova, Jean-Laurent, Picard, Capucine, Tangye, Stuart G, Ma, Cindy S, Johnstone, Ricky W, Randall, Katrina L, Oliaro, Jane

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Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity von Hawkins, Edwin D., Oliaro, Jane, Kallies, Axel, Belz, Gabrielle T., Filby, Andrew, Hogan, Thea, Haynes, Nicole, Ramsbottom, Kelly M., Van Ham, Vanessa, Kinwell, Tanja, Seddon, Benedict, Davies, Derek, Tarlinton, David, Lew, Andrew M., Humbert, Patrick O., Russell, Sarah M.

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BET Inhibition Enhances TNF-Mediated Antitumor Immunity von Wellinger, Lisa C, Hogg, Simon J, Newman, Dane M, Friess, Thomas, Geiss, Daniela, Michie, Jessica, Ramsbottom, Kelly M, Bacac, Marina, Fauti, Tanja, Marbach, Daniel, Jarassier, Laura, Thienger, Phillip, Paehler, Axel, Cluse, Leonie A, Kearney, Conor J, Vervoort, Stephin J, Trapani, Joseph A, Oliaro, Jane, Shortt, Jake, Ruefli-Brasse, Astrid, Rohle, Daniel, Johnstone, Ricky W

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Combined BRAF, MEK, and CDK4/6 Inhibition Depletes Intratumoral Immune-Potentiating Myeloid Populations in Melanoma von Lelliott, Emily J, Mangiola, Stefano, Ramsbottom, Kelly M, Zethoven, Magnus, Lim, Lydia, Lau, Peter K H, Oliver, Amanda J, Martelotto, Luciano G, Kirby, Laura, Martin, Claire, Patel, Riyaben P, Slater, Alison, Cullinane, Carleen, Papenfuss, Anthony T, Haynes, Nicole M, McArthur, Grant A, Oliaro, Jane, Sheppard, Karen E

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