Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease von Gonorazky, Hernan D., Naumenko, Sergey, Ramani, Arun K., Nelakuditi, Viswateja, Mashouri, Pouria, Wang, Peiqui, Kao, Dennis, Ohri, Krish, Viththiyapaskaran, Senthuri, Tarnopolsky, Mark A., Mathews, Katherine D., Moore, Steven A., Osorio, Andres N., Villanova, David, Kemaladewi, Dwi U., Cohn, Ronald D., Brudno, Michael, Dowling, James J.

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Splicing is an alternate oncogenic pathway activation mechanism in glioma von Siddaway, Robert, Milos, Scott, Vadivel, Arun Kumaran Anguraj, Dobson, Tara H. W., Swaminathan, Jyothishmathi, Ryall, Scott, Pajovic, Sanja, Patel, Palak G., Nazarian, Javad, Becher, Oren, Brudno, Michael, Ramani, Arun, Gopalakrishnan, Vidya, Hawkins, Cynthia

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Comparative RNAi screens in C. elegans and C. briggsae reveal the impact of developmental system drift on gene function von Verster, Adrian J, Ramani, Arun K, McKay, Sheldon J, Fraser, Andrew G

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How complete are current yeast and human protein-interaction networks? von Hart, G Traver, Ramani, Arun K, Marcotte, Edward M

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Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation von Ip, Joanna Y, Schmidt, Dominic, Pan, Qun, Ramani, Arun K, Fraser, Andrew G, Odom, Duncan T, Blencowe, Benjamin J

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A Pair of RNA-Binding Proteins Controls Networks of Splicing Events Contributing to Specialization of Neural Cell Types von Norris, Adam D., Gao, Shangbang, Norris, Megan L., Ray, Debashish, Ramani, Arun K., Fraser, Andrew G., Morris, Quaid, Hughes, Timothy R., Zhen, Mei, Calarco, John A.

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MetaFusion: a high-confidence metacaller for filtering and prioritizing RNA-seq gene fusion candidates von Apostolides, Michael, Jiang, Yue, Husić, Mia, Siddaway, Robert, Hawkins, Cynthia, Turinsky, Andrei L, Brudno, Michael, Ramani, Arun K

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Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated With Monogenic Variants, Identified by Whole-Exome Sequencing in 1000 Children at a Single Center von Crowley, Eileen, Warner, Neil, Pan, Jie, Khalouei, Sam, Elkadri, Abdul, Fiedler, Karoline, Foong, Justin, Turinsky, Andrei L., Bronte-Tinkew, Dana, Zhang, Shiqi, Hu, Jamie, Tian, David, Li, Dalin, Horowitz, Julie, Siddiqui, Iram, Upton, Julia, Roifman, Chaim M., Church, Peter C., Wall, Donna A., Ramani, Arun K., Kotlarz, Daniel, Klein, Christoph, Uhlig, Holm, Snapper, Scott B., Gonzaga-Jauregui, Claudia, Paterson, Andrew D., McGovern, Dermot P.B., Brudno, Michael, Walters, Thomas D., Griffiths, Anne M., Muise, Aleixo M.

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Control of Long-Term Synaptic Potentiation and Learning by Alternative Splicing of the NMDA Receptor Subunit GluN1 von Sengar, Ameet S., Li, Hongbin, Zhang, Wenbo, Leung, Celeste, Ramani, Arun K., Saw, Ner Mu, Wang, Yongqian, Tu, YuShan, Ross, P. Joel, Scherer, Stephen W., Ellis, James, Brudno, Michael, Jia, Zhengping, Salter, Michael W.

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Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic pain von Ghazisaeidi, Shahrzad, Muley, Milind M, Tu, YuShan, Finn, David P, Kolahdouzan, Mahshad, Pitcher, Graham M, Kim, Doyeon, Sengar, Ameet S, Ramani, Arun K, Brudno, Michael, Salter, Michael W

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Clinical Implementation of MetaFusion for Accurate Cancer-Driving Fusion Detection from RNA Sequencing von Apostolides, Michael, Li, Michael, Arnoldo, Anthony, Ku, Michelle, Husić, Mia, Ramani, Arun K, Brudno, Michael, Turinsky, Andrei, Hawkins, Cynthia, Siddaway, Robert

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Identification of complex genomic rearrangements in cancers using CouGaR von Dzamba, Misko, Ramani, Arun K, Buczkowicz, Pawel, Jiang, Yue, Yu, Man, Hawkins, Cynthia, Brudno, Michael

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The Majority of Animal Genes Are Required for Wild-Type Fitness von Ramani, Arun K., Chuluunbaatar, Tungalag, Verster, Adrian J., Na, Hong, Vu, Victoria, Pelte, Nadège, Wannissorn, Nattha, Jiao, Alan, Fraser, Andrew G.

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Genome-wide analysis of alternative splicing in Caenorhabditis elegans von Ramani, Arun K, Calarco, John A, Pan, Qun, Mavandadi, Sepand, Wang, Ying, Nelson, Andrew C, Lee, Leo J, Morris, Quaid, Blencowe, Benjamin J, Zhen, Mei, Fraser, Andrew G

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Tamoxifen therapy in a murine model of myotubular myopathy von Maani, Nika, Sabha, Nesrin, Rezai, Kamran, Ramani, Arun, Groom, Linda, Eltayeb, Nadine, Mavandadnejad, Faranak, Pang, Andrea, Russo, Giulia, Brudno, Michael, Haucke, Volker, Dirksen, Robert T., Dowling, James J.

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Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease von Gonorazky, Hernan D., Naumenko, Sergey, Ramani, Arun K., Nelakuditi, Viswateja, Mashouri, Pouria, Wang, Peiqui, Kao, Dennis, Ohri, Krish, Viththiyapaskaran, Senthuri, Tarnopolsky, Mark A., Mathews, Katherine D., Moore, Steven A., Osorio, Andres N., Villanova, David, Kemaladewi, Dwi U., Cohn, Ronald D., Brudno, Michael, Dowling, James J.

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Basophil activation test shows high accuracy in the diagnosis of peanut and tree nut allergy: The Markers of Nut Allergy Study von Duan, Lucy, Celik, Alper, Hoang, Jennifer A., Schmidthaler, Klara, So, Delvin, Yin, Xiaojun, Ditlof, Christina M., Ponce, Marta, Upton, Julia E.M., Lee, Jean‐Soo, Hung, Lisa, Breiteneder, Heimo, Palladino, Chiara, Atkinson, Adelle R., Kim, Vy H.D., Berenjy, Alireza, Asper, Maria, Hummel, David, Wong, Samantha, Alexanian‐Farr, Mara, Magder, Ahuva, Chinthrajah, Sharon R., Mukai, Kaori, Tsai, Mindy, Nadeau, Kari, Galli, Stephen J., Ramani, Arun K., Szepfalusi, Zsolt, Eiwegger, Thomas

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Protein interaction networks from yeast to human von Bork, Peer, Jensen, Lars J, von Mering, Christian, Ramani, Arun K, Lee, Insuk, Marcotte, Edward M

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Genomics4RD: An integrated platform to share Canadian deep‐phenotype and multiomic data for international rare disease gene discovery von Driver, Hannah G., Hartley, Taila, Price, E. Magda, Turinsky, Andrei L., Buske, Orion J., Osmond, Matthew, Ramani, Arun K., Kirby, Emily, Kernohan, Kristin D., Couse, Madeline, Elrick, Hillary, Lu, Kevin, Mashouri, Pouria, Mohan, Aarthi, So, Delvin, Klamann, Conor, Le, Hannah G. B. H., Herscovich, Andrea, Marshall, Christian R., Statia, Andrew, Canada Consortium, Care4Rare, Knoppers, Bartha M., Brudno, Michael, Boycott, Kym M.

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CReSCENT: CanceR Single Cell ExpressioN Toolkit von Mohanraj, Suluxan, Díaz-Mejía, J Javier, Pham, Martin D, Elrick, Hillary, Husić, Mia, Rashid, Shaikh, Luo, Ping, Bal, Prabnur, Lu, Kevin, Patel, Samarth, Mahalanabis, Alaina, Naidas, Alaine, Christensen, Erik, Croucher, Danielle, Richards, Laura M, Shooshtari, Parisa, Brudno, Michael, Ramani, Arun K, Pugh, Trevor J

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