Monitoring tumour burden and therapeutic response through analysis of circulating tumour DNA and extracellular RNA in multiple myeloma patients von Mithraprabhu, Sridurga, Morley, Rachel, Khong, Tiffany, Kalff, Anna, Bergin, Krystal, Hocking, Jay, Savvidou, Ioanna, Bowen, Kathryn M., Ramachandran, Malarmathy, Choi, Kawa, Wong, Boris Ka Leong, Reynolds, John, Spencer, Andrew

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Planned withdrawal of dexamethasone after pomalidomide low-dose dexamethasone induction for lenalidomide-refractory multiple myeloma (ALLG MM14) von Kalff, Anna, Khong, Tiffany, Ramachandran, Malarmathy, Ho, P Joy, Mollee, Peter, D'Rozario, James, Taylor, Kerry, Estell, Jane, Norton, Sam, Kemp, Roslyn, Mitchell, Andrew J, Reynolds, John, Kennedy, Nola, Quach, Hang, Spencer, Andrew

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Global Regulator MorA Affects Virulence-Associated Protease Secretion in Pseudomonas aeruginosa PAO1 von Ravichandran, Ayshwarya, Ramachandran, Malarmathy, Suriyanarayanan, Tanujaa, Wong, Chui Ching, Swarup, Sanjay

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Cubic membranes: a structure-based design for DNA uptake von Almsherqi, Zakaria, Hyde, Stephen, Ramachandran, Malarmathy, Deng, Yuru

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Changes in immune cell populations following KappaMab, lenalidomide and low‐dose dexamethasone treatment in multiple myeloma von Norton, Samuel E, Khong, Tiffany, Ramachandran, Malarmathy, Highton, Andrew J, Ward‐Hartstonge, Kirsten A, Shortt, Jake, Spencer, Andrew, Kemp, Roslyn A

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Cell Free MYC DNA Copy Number Identifies High-Risk Smouldering Myeloma and Newly Diagnosed Multiple Myeloma von Wong, Daniel, Reynold, John, Wellard, Cameron, Bingham, Nicholas, Zhao, Jessie, Ramachandran, Malarmathy, Quach, Hang, Gibbs, Simon, Khong, Tiffany T., Mithraprabhu, Sridurga, Spencer, Andrew

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Multiple Myeloma-Derived Circulating Extracellular Vesicles Affect Normal Human Stromal Cell Behaviour and Promote Tumor Progression: A Multi-Omic Approach von Reale, Antonia, Carmichael, Irena, Xu, Rong, Fang, Haoyun, Shah, Jaynish S, Khong, Tiffany, Bingham, Nicholas, Ramachandran, Malarmathy, Chen, Maoshan, Greening, David W, Spencer, Andrew

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Utility of Circulating Cell-Free RNA Analysis for the Characterization of Global Transcriptome Profiles of Multiple Myeloma Patients von Chen, Maoshan, Mithraprabhu, Sridurga, Ramachandran, Malarmathy, Choi, Kawa, Khong, Tiffany, Spencer, Andrew

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Human myeloma cell‐ and plasma‐derived extracellular vesicles contribute to functional regulation of stromal cells von Reale, Antonia, Carmichael, Irena, Xu, Rong, Mithraprabhu, Sridurga, Khong, Tiffany, Chen, Maoshan, Fang, Haoyun, Savvidou, Ioanna, Ramachandran, Malarmathy, Bingham, Nicholas, Simpson, Richard J., Greening, David W., Spencer, Andrew

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DNA-Repair Gene Mutations Are Highly Prevalent in Circulating Tumour DNA from Multiple Myeloma Patients von Mithraprabhu, Sridurga, Hocking, Jay, Ramachandran, Malarmathy, Choi, Kawa, Klarica, Daniela, Khong, Tiffany, Reynolds, John, Spencer, Andrew

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Immune Cell Profiles in Patients Treated with Lenalidomide and Alternate Day Prednisolone Maintenance Post Upfront ASCT for Multiple Myeloma (LEOPARD Trial) von Kalff, Anna, Norton, Sam, Khong, Tiffany, Ramachandran, Malarmathy, Young, Mary H., Pierceall, William, Thakurta, Anjan, Oppermann, Udo, Guo, Manman, Reynolds, John, Spencer, Andrew

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Phase II trial of single‐agent panobinostat consolidation improves responses after sub‐optimal transplant outcomes in multiple myeloma von Mithraprabhu, Sridurga, Kalff, Anna, Gartlan, Kate H., Savvidou, Ioanna, Khong, Tiffany, Ramachandran, Malarmathy, Cooke, Rachel E., Bowen, Kathryn, Hill, Geoffrey R., Reynolds, John, Spencer, Andrew

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Identification of Novel Immune Cell Populations in Lenalidomide Refractory Relapsed Multiple Myeloma Patients Treated with Pomalidomide and Low Dose Dexamethasone von Kalff, Anna, Khong, Tiffany, Ramachandran, Malarmathy, Norton, Sam, Mitchell, Andrew, Reynolds, John, Quach, Hang, Ho, P Joy, Horvath, Noemi, Mollee, Peter, Kennedy, Nola, Kemp, Roslyn, Spencer, Andrew

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Identification of Acetylation, Immune Cell Alterations and Gene Signature As Dynamic Biomarkers of Response to Panobinostat Treatment in Multiple Myeloma Patients von Mithraprabhu, Sridurga, Savvidou, Ioanna, Ramachandran, Malarmathy, Kalff, Anna, Khong, Tiffany T., Reed, Kate, Reynolds, John, Spencer, Andrew

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DNA-repair gene mutations are prevalent in circulating tumour DNA from advanced multiple myeloma patients von Spencer, Andrew, Ramachandran, Malarmathy, choi, Kawa, hocking, jay, Klarica, Daniela, Khong, Tiffany, Reynolds, John, Mithraprabhu, Sridurga

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P-055: Extracellular RNA: an emerging biomarker for therapeutic monitoring in multiple myeloma von Mithraprabhu, Sridurga, Morley, Rachel, Chen, Moashan, Ramachandran, Malarmathy, Choi, Kawa, Kalff, Anna, Bergin, Krystal, Yuen, Flora, Shortt, Jake, Khong, Tiffany, Reynolds, John, Spencer, Andrew

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TOP2A Knockdown Resensitizes Carfilzomib-Resistant Hmcls to Carfilzomib von Reale, Antonia, Khong, Tiffany T., Mithraprabhu, Sridurga, Savvidou, Ioanna, Ramachandran, Malarmathy, Spencer, Andrew

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A 2-Stage Phase II Study of Panobinostat Consolidation in Multiple Myeloma (MM) Patients with < CR Following Single High-Dose Chemotherapy (HDT) Conditioned Autologous Stem Cell Tr... von Kalff, Anna, Mithraprabhu, Sridurga, Khong, Tiffany T., Ramachandran, Malarmathy, Reed, Kate, Quach, Hang, Walker, Patricia A., Bergin, Krystal, Spencer, Andrew

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TOP2A a New Predictive Marker of Response to Carfilzomib in Multiple Myeloma von Reale, Antonia, Khong, Tiffany, Mithraprabhu, Sridurga, Reynolds, John, Ramachandran, Malarmathy, Savvidou, Ioanna, Bergin, Krystal, Hocking, Jay, Spencer, Andrew

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Abstract 2366: Myeloma-derived circulating extracellular vesicles affect human stromal cell behaviour and promote tumor progression: A multi-omic approach von Reale, Antonia, Xu, Rong, Carmichael, Irena, Fang, Haoyun, Sha, Jaynish S, Khong, Tiffany, Bingham, Nicholas, Ramachandran, Malarmathy, Chen, Maoshan, Greening, David W, Spencer, Andrew

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