Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth von Yang, Lifeng, Achreja, Abhinav, Yeung, Tsz-Lun, Mangala, Lingegowda S., Jiang, Dahai, Han, Cecil, Baddour, Joelle, Marini, Juan C., Ni, Joseph, Nakahara, Ryuichi, Wahlig, Stephen, Chiba, Lisa, Kim, Sun Hye, Morse, Joshua, Pradeep, Sunila, Nagaraja, Archana Sidalaghatta, Haemmerle, Monika, Kyunghee, Noh, Derichsweiler, Mathew, Plackemeier, Thomas, Mercado-Uribe, Imelda, Lopez-Berestein, Gabriel, Moss, Tyler, Ram, Prahlad T., Liu, Jinsong, Lu, Xiongbin, Mok, Samuel C., Sood, Anil K., Nagrath, Deepak

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Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism von Zhao, Hongyun, Yang, Lifeng, Baddour, Joelle, Achreja, Abhinav, Bernard, Vincent, Moss, Tyler, Marini, Juan C, Tudawe, Thavisha, Seviour, Elena G, San Lucas, F Anthony, Alvarez, Hector, Gupta, Sonal, Maiti, Sourindra N, Cooper, Laurence, Peehl, Donna, Ram, Prahlad T, Maitra, Anirban, Nagrath, Deepak

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NetWalker: a contextual network analysis tool for functional genomics von Komurov, Kakajan, Dursun, Serkan, Erdin, Serkan, Ram, Prahlad T

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A pan-cancer proteomic perspective on The Cancer Genome Atlas von Akbani, Rehan, Ng, Patrick Kwok Shing, Werner, Henrica M. J., Shahmoradgoli, Maria, Zhang, Fan, Ju, Zhenlin, Liu, Wenbin, Yang, Ji-Yeon, Yoshihara, Kosuke, Li, Jun, Ling, Shiyun, Seviour, Elena G., Ram, Prahlad T., Minna, John D., Diao, Lixia, Tong, Pan, Heymach, John V., Hill, Steven M., Dondelinger, Frank, Städler, Nicolas, Byers, Lauren A., Meric-Bernstam, Funda, Weinstein, John N., Broom, Bradley M., Verhaak, Roeland G. W., Liang, Han, Mukherjee, Sach, Lu, Yiling, Mills, Gordon B.

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Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer von Yang, Lifeng, Moss, Tyler, Mangala, Lingegowda S, Marini, Juan, Zhao, Hongyun, Wahlig, Stephen, Armaiz‐Pena, Guillermo, Jiang, Dahai, Achreja, Abhinav, Win, Julia, Roopaimoole, Rajesha, Rodriguez‐Aguayo, Cristian, Mercado‐Uribe, Imelda, Lopez‐Berestein, Gabriel, Liu, Jinsong, Tsukamoto, Takashi, Sood, Anil K., Ram, Prahlad T, Nagrath, Deepak

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes von Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly, Onder, Tamer T., Gupta, Piyush B., Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Lander, Eric S., Rosen, Jeffrey M., Weinberg, Robert A., Mani, Sendurai A.

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Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis von LADEVAIA, Sergio, YILING LU, MORALES, Fabiana C, MILLS, Gordon B, RAM, Prahlad T

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Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery von Hennessy, Bryan T., Smith, Debra L., Ram, Prahlad T., Lu, Yiling, Mills, Gordon B.

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Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling von Parashar, Deepak, Nair, Bindu, Geethadevi, Anjali, George, Jasmine, Nair, Ajay, Tsaih, Shirng-Wern, Kadamberi, Ishaque P, Gopinadhan Nair, Gopa Kumar, Lu, Yiling, Ramchandran, Ramani, Uyar, Denise S, Rader, Janet S, Ram, Prahlad T, Mills, Gordon B, Pradeep, Sunila, Chaluvally-Raghavan, Pradeep

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A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease von Nishikawa, Taichiro, Bellance, Nadège, Damm, Aaron, Bing, Han, Zhu, Zhen, Handa, Kan, Yovchev, Mladen I, Sehgal, Vasudha, Moss, Tyler J, Oertel, Michael, Ram, Prahlad T, Pipinos, Iraklis I, Soto-Gutierrez, Alejandro, Fox, Ira J, Nagrath, Deepak

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Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction von Allen, Julie K, Armaiz-Pena, Guillermo N, Nagaraja, Archana S, Sadaoui, Nouara C, Ortiz, Tatiana, Dood, Robert, Ozcan, Merve, Herder, Danielle M, Haemmerle, Monika, Gharpure, Kshipra M, Rupaimoole, Rajesha, Previs, Rebecca A, Wu, Sherry Y, Pradeep, Sunila, Xu, Xiaoyun, Han, Hee Dong, Zand, Behrouz, Dalton, Heather J, Taylor, Morgan, Hu, Wei, Bottsford-Miller, Justin, Moreno-Smith, Myrthala, Kang, Yu, Mangala, Lingegowda S, Rodriguez-Aguayo, Cristian, Sehgal, Vasudha, Spaeth, Erika L, Ram, Prahlad T, Wong, Stephen T C, Marini, Frank C, Lopez-Berestein, Gabriel, Cole, Steve W, Lutgendorf, Susan K, De Biasi, Mariella, Sood, Anil K

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G Protein Pathways von Neves, Susana R., Ram, Prahlad T., Iyengar, Ravi

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Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data von Komurov, Kakajan, White, Michael A, Ram, Prahlad T

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CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance von Ma, Shaolin, Mangala, Lingegowda S., Hu, Wen, Bayaktar, Emine, Yokoi, Akira, Hu, Wei, Pradeep, Sunila, Lee, Sanghoon, Piehowski, Paul D., Villar-Prados, Alejandro, Wu, Sherry Y., McGuire, Michael H., Lara, Olivia D., Rodriguez-Aguayo, Cristian, LaFargue, Christopher J., Jennings, Nicholas B., Rodland, Karin D., Liu, Tao, Kundra, Vikas, Ram, Prahlad T., Ramakrishnan, Sundaram, Lopez-Berestein, Gabriel, Coleman, Robert L., Sood, Anil K.

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MAP Kinase Phosphatase as a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network von Bhalla, Upinder S., Ram, Prahlad T., Iyengar, Ravi

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The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells von Komurov, Kakajan, Tseng, Jen‐Te, Muller, Melissa, Seviour, Elena G, Moss, Tyler J, Yang, Lifeng, Nagrath, Deepak, Ram, Prahlad T

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The signaling petri net-based simulator: a non-parametric strategy for characterizing the dynamics of cell-specific signaling networks von Ruths, Derek, Muller, Melissa, Tseng, Jen-Te, Nakhleh, Luay, Ram, Prahlad T

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The ZNF304-integrin axis protects against anoikis in cancer von Aslan, Burcu, Monroig, Paloma, Hsu, Ming-Chuan, Pena, Guillermo Armaiz, Rodriguez-Aguayo, Cristian, Gonzalez-Villasana, Vianey, Rupaimoole, Rajesha, Nagaraja, Archana Sidalaghatta, Mangala, Selanere, Han, Hee-Dong, Yuca, Erkan, Wu, Sherry Y., Ivan, Cristina, Moss, Tyler J., Ram, Prahlad T., Wang, Huamin, Gol-Chambers, Alexandra, Ozkayar, Ozgur, Kanlikilicer, Pinar, Fuentes-Mattei, Enrique, Kahraman, Nermin, Pradeep, Sunila, Ozpolat, Bulent, Tucker, Susan, Hung, Mien-Chie, Baggerly, Keith, Bartholomeusz, Geoffrey, Calin, George, Sood, Anil K., Lopez-Berestein, Gabriel

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Formation of Regulatory Patterns During Signal Propagation in a Mammalian Cellular Network von Ma'ayan, Avi, Jenkins, Sherry L, Neves, Susana, Hasseldine, Anthony, Grace, Elizabeth, Dubin-Thaler, Benjamin, Eungdamrong, Narat J, Weng, Gehzi, Ram, Prahlad T, Rice, J. Jeremy, Kershenbaum, Aaron, Stolovitzky, Gustavo A, Blitzer, Robert D, Iyengar, Ravi

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Robust Selection Algorithm (RSA) for Multi-Omic Biomarker Discovery; Integration with Functional Network Analysis to Identify miRNA Regulated Pathways in Multiple Cancers von Sehgal, Vasudha, Seviour, Elena G, Moss, Tyler J, Mills, Gordon B, Azencott, Robert, Ram, Prahlad T

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