The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency von Gatti, Marco, Imhof, Ralph, Huang, Qingyao, Baudis, Michael, Altmeyer, Matthias

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Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance von Michelena, Jone, Lezaja, Aleksandra, Teloni, Federico, Schmid, Thomas, Imhof, Ralph, Altmeyer, Matthias

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Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin von Pellegrino, Stefania, Michelena, Jone, Teloni, Federico, Imhof, Ralph, Altmeyer, Matthias

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Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins von Nowak, Kathrin, Rosenthal, Florian, Karlberg, Tobias, Bütepage, Mareike, Thorsell, Ann-Gerd, Dreier, Birgit, Grossmann, Jonas, Sobek, Jens, Imhof, Ralph, Lüscher, Bernhard, Schüler, Herwig, Plückthun, Andreas, Leslie Pedrioli, Deena M., Hottiger, Michael O.

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Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases von Rosenthal, Florian, Feijs, Karla L H, Frugier, Emilie, Bonalli, Mario, Forst, Alexandra H, Imhof, Ralph, Winkler, Hans C, Fischer, David, Caflisch, Amedeo, Hassa, Paul O, Lüscher, Bernhard, Hottiger, Michael O

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RPA shields inherited DNA lesions for post-mitotic DNA synthesis von Lezaja, Aleksandra, Panagopoulos, Andreas, Wen, Yanlin, Carvalho, Edison, Imhof, Ralph, Altmeyer, Matthias

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Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle von Pirinen, Eija, Cantó, Carles, Jo, Young Suk, Morato, Laia, Zhang, Hongbo, Menzies, Keir J., Williams, Evan G., Mouchiroud, Laurent, Moullan, Norman, Hagberg, Carolina, Li, Wei, Timmers, Silvie, Imhof, Ralph, Verbeek, Jef, Pujol, Aurora, van Loon, Barbara, Viscomi, Carlo, Zeviani, Massimo, Schrauwen, Patrick, Sauve, Anthony A., Schoonjans, Kristina, Auwerx, Johan

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CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks von Rother, Magdalena B., Pellegrino, Stefania, Smith, Rebecca, Gatti, Marco, Meisenberg, Cornelia, Wiegant, Wouter W., Luijsterburg, Martijn S., Imhof, Ralph, Downs, Jessica A., Vertegaal, Alfred C. O., Huet, Sébastien, Altmeyer, Matthias, van Attikum, Haico

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DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass von Maga, Giovanni, Crespan, Emmanuele, Markkanen, Enni, lmhof, Ralph, Furrer, Antonia, Villani, Giuseppe, Hübscher, Ulrich, van Loon, Barbara

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Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair von Crespan, Emmanuele, Furrer, Antonia, Rösinger, Marcel, Bertoletti, Federica, Mentegari, Elisa, Chiapparini, Giulia, Imhof, Ralph, Ziegler, Nathalie, Sturla, Shana J., Hübscher, Ulrich, van Loon, Barbara, Maga, Giovanni

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Phase separation of 53BP1 determines liquid‐like behavior of DNA repair compartments von Kilic, Sinan, Lezaja, Aleksandra, Gatti, Marco, Bianco, Eliana, Michelena, Jone, Imhof, Ralph, Altmeyer, Matthias

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Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis von Hottiger, Michael O, Hasan, Sameez, Hassa, Paul O, Imhof, Ralph

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Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions von Michelena, Jone, Gatti, Marco, Teloni, Federico, Imhof, Ralph, Altmeyer, Matthias

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Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres von Spegg, Vincent, Panagopoulos, Andreas, Stout, Merula, Krishnan, Aswini, Reginato, Giordano, Imhof, Ralph, Roschitzki, Bernd, Cejka, Petr, Altmeyer, Matthias

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Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability von Teloni, Federico, Michelena, Jone, Lezaja, Aleksandra, Kilic, Sinan, Ambrosi, Christina, Menon, Shruti, Dobrovolna, Jana, Imhof, Ralph, Janscak, Pavel, Baubec, Tuncay, Altmeyer, Matthias

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Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions von Michelena, Jone, Gatti, Marco, Teloni, Federico, Imhof, Ralph, Altmeyer, Matthias

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RPA shields inherited DNA lesions for post-mitotic DNA synthesis von Lezaja, Aleksandra, Panagopoulos, Andreas, Wen, Yanlin, Carvalho, Edison, Imhof, Ralph, Altmeyer, Matthias

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Comprehensive ADP‐ribosylome analysis identifies tyrosine as an ADP‐ribose acceptor site von Leslie Pedrioli, Deena M, Leutert, Mario, Bilan, Vera, Nowak, Kathrin, Gunasekera, Kapila, Ferrari, Elena, Imhof, Ralph, Malmström, Lars, Hottiger, Michael O

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Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system von Suter, Bernhard, Fetchko, Michael J, Imhof, Ralph, Graham, Christopher I, Stoffel-Studer, Ingrid, Zbinden, Caroline, Raghavan, Maanasa, Lopez, Lianet, Beneti, Lucija, Hort, Jacqueline, Fillingham, Jeffrey, Greenblatt, Jack F, Giaever, Guri, Nislow, Corey, Stagljar, Igor

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Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments von Kilic, Sinan, Lezaja, Aleksandra, Gatti, Marco, Bianco, Eliana, Michelena, Jone, Imhof, Ralph, Altmeyer, Matthias

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