Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo von Soccio, Raymond E., Chen, Eric R., Rajapurkar, Satyajit R., Safabakhsh, Pegah, Marinis, Jill M., Dispirito, Joanna R., Emmett, Matthew J., Briggs, Erika R., Fang, Bin, Everett, Logan J., Lim, Hee-Woong, Won, Kyoung-Jae, Steger, David J., Wu, Ying, Civelek, Mete, Voight, Benjamin F., Lazar, Mitchell A.

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Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all- trans retinoic acid in acute myeloid leukemia across sub... von Smitheman, Kimberly N, Severson, Tesa M, Rajapurkar, Satyajit R, McCabe, Michael T, Karpinich, Natalie, Foley, James, Pappalardi, Melissa B, Hughes, Ashley, Halsey, Wendy, Thomas, Elizabeth, Traini, Christopher, Federowicz, Kelly E, Laraio, Jenny, Mobegi, Fredrick, Ferron-Brady, Geraldine, Prinjha, Rabinder K, Carpenter, Christopher L, Kruger, Ryan G, Wessels, Lodewyk, Mohammad, Helai P

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Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss von Fedoriw, Andrew, Rajapurkar, Satyajit R., O'Brien, Shane, Gerhart, Sarah V., Mitchell, Lorna H., Adams, Nicholas D., Rioux, Nathalie, Lingaraj, Trupti, Ribich, Scott A., Pappalardi, Melissa B., Shah, Niyant, Laraio, Jenny, Liu, Yan, Butticello, Michael, Carpenter, Chris L., Creasy, Caretha, Korenchuk, Susan, McCabe, Michael T., McHugh, Charles F., Nagarajan, Raman, Wagner, Craig, Zappacosta, Francesca, Annan, Roland, Concha, Nestor O., Thomas, Roberta A., Hart, Timothy K., Smith, Jesse J., Copeland, Robert A., Moyer, Mikel P., Campbell, John, Stickland, Kim, Mills, James, Jacques-O’Hagan, Suzanne, Allain, Christina, Johnston, Danielle, Raimondi, Alejandra, Porter Scott, Margaret, Waters, Nigel, Swinger, Kerren, Boriack-Sjodin, Ann, Riera, Tom, Shapiro, Gideon, Chesworth, Richard, Prinjha, Rabinder K., Kruger, Ryan G., Barbash, Olena, Mohammad, Helai P.

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MEK inhibitors overcome resistance to BET inhibition across a number of solid and hematologic cancers von Wyce, Anastasia, Matteo, Jeanne J., Foley, Shawn W., Felitsky, Daniel J., Rajapurkar, Satyajit R., Zhang, Xi-Ping, Musso, Melissa C., Korenchuk, Susan, Karpinich, Natalie O., Keenan, Kathryn M., Stern, Melissa, Mathew, Lijoy K., McHugh, Charles F., McCabe, Michael T., Tummino, Peter J., Kruger, Ryan G., Carpenter, Christopher, Barbash, Olena

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Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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Targeting PPAR[gamma] in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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Genetic Variation Determines PPARγ Function and Antidiabetic Drug Response In Vivo von Soccio, Raymond E., Chen, Eric R., Rajapurkar, Satyajit R., Safabakhsh, Pegah, Marinis, Jill M., Dispirito, Joanna R., Emmett, Matthew J., Briggs, Erika R., Fang, Bin, Everett, Logan J., Lim, Hee-Woong, Won, Kyoung-Jae, Steger, David J., Wu, Ying, Civelek, Mete, Voight, Benjamin F., Lazar, Mitchell A.

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Targeting PPAR[gamma] in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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Targeting PPAR[gamma] in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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