Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes von Marselli, Lorella, Piron, Anthony, Suleiman, Mara, Colli, Maikel L., Yi, Xiaoyan, Khamis, Amna, Carrat, Gaelle R., Rutter, Guy A., Bugliani, Marco, Giusti, Laura, Ronci, Maurizio, Ibberson, Mark, Turatsinze, Jean-Valery, Boggi, Ugo, De Simone, Paolo, De Tata, Vincenzo, Lopes, Miguel, Nasteska, Daniela, De Luca, Carmela, Tesi, Marta, Bosi, Emanuele, Singh, Pratibha, Campani, Daniela, Schulte, Anke M., Solimena, Michele, Hecht, Peter, Rady, Brian, Bakaj, Ivona, Pocai, Alessandro, Norquay, Lisa, Thorens, Bernard, Canouil, Mickaël, Froguel, Philippe, Eizirik, Decio L., Cnop, Miriam, Marchetti, Piero

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PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells von Rady, Brian, Nishio, Takahiro, Dhar, Debanjan, Liu, Xiao, Erion, Mark, Kisseleva, Tatiana, Brenner, David A., Pocai, Alessandro

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A FFAR1 full agonist restores islet function in models of impaired glucose-stimulated insulin secretion and diabetic non-human primates von Rady, Brian, Liu, Jianying, Huang, Hui, Bakaj, Ivona, Qi, Jenson, Lee, S P, Martin, Tonya, Norquay, Lisa, Player, Mark, Pocai, Alessandro

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Phase 1 Trials of PNPLA3 siRNA in I148M Homozygous Patients with MAFLD von Fabbrini, Elisa, Rady, Brian, Koshkina, Anastasiya, Jeon, Jae Yoon, Ayyar, Vivaswath S., Gargano, Cynthia, DiProspero, Nicholas, Wendel, Susan, Hegge, Julia, Hamilton, Holly, Ding, Zhi-Ming, Afrazi, Maria, Nicholas, Anthony, Pei, Tao, Nakano, Masayoshi, Ouchi, Shohei, Saito, Yuki, Yamashita, Aimi, Tamamura, Ryo, Salazar, Hernan, Shapiro, Craig, Yoshihara, Tatsuya, Yonemura, Takuma, Inoue, Satoshi, Matsuoka, Osamu, Erion, Mark, Pocai, Alessandro, Makimura, Hideo

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243-OR: A Novel Platform for Genetic Screening of NAFLD-Associated Genes Identifies UBE2G2 and Other Genes That Alter Hepatic Lipid Accumulation von HU, SIQI, ADITI SRI VAISHNAVI KHANDAVILLI, SESHA, DIAO, RACHEL Y., RAUM, JEFFREY, AZHAR, NABIL, BAKAJ, IVONA, COWLEY, GLENN, RADY, BRIAN, REILLY, DERMOT F., MAJITHIA, AMIT R.

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GPR40-Mediated G α 12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets von Rives, Marie-Laure, Rady, Brian, Swanson, Nadia, Zhao, Shuyuan, Qi, Jenson, Arnoult, Eric, Bakaj, Ivona, Mancini, Arturo, Breton, Billy, Lee, S Paul, Player, Mark R, Pocai, Alessandro

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Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis von Rady, Brian, Chen, Yanmei, Vaca, Pilar, Wang, Qian, Wang, Yong, Salmon, Patrick, Oberholzer, José

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Therapeutic Potential of EP3 Receptor Antagonists for Treatment of Noninsulin Dependent Diabetes Mellitus across Multiple Preclinical Models von RANKIN, MATTHEW M., GUO, LILI, BAKAJ, IVONA, HO, GEORGE, RADY, BRIAN, ZHAO, SHUYUAN, STAHLE, PAUL L., GHOSH, AVIJIT, SHI, YIFAN, PATEL, SHEFALI, TRYPUTSEN, VOLHA, LUBOMIRSKI, MARIUSZ, ZHANG, XUQING, ZHU, BIN, WINTERS, MICHAEL P., MACIELAG, MARK J., NORQUAY, LISA D.

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Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists von Huang, Hui, Winters, Michael P., Meegalla, Sanath K., Arnoult, Eric, Paul Lee, S., Zhao, Shuyuan, Martin, Tonya, Rady, Brian, Liu, Jianying, Towers, Meghan, Otieno, Monicah, Xu, Fran, Lim, Heng Keang, Silva, Jose, Pocai, Alessandro, Player, Mark R.

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Discovery of a novel potent GPR40 full agonist von Meegalla, Sanath K., Huang, Hui, Martin, Tonya, Xu, June, Zhao, Shuyuan, Liu, Jianying, Hall, Meghan, Gunnet, Joe, Wang, Yuanping, Rady, Brian, Silva, Jose, Otieno, Monicah, Arnoult, Eric, Paul Lee, S., Pocai, Alessandro, Player, Mark R.

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FFAR1 Agonism Restores Insulin Secretion in Rodents, Human Islets, and Diabetic Monkeys von Liu, Jianying, Lee, Seunghun P, Martin, Tonya, Rady, Brian, Meegalla, Sanath, Huang, Hui, Winters, Michael P, Norquay, Lisa D, Qi, Jenson, Du, Fuyong, Nawrocki, Andrea R, Player, Mark, Pocai, Alessandro

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PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells von Brian Rady, Takahiro Nishio, Debanjan Dhar, Xiao Liu, Mark Erion, Tatiana Kisseleva, David A. Brenner, Alessandro Pocai

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Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α‑Fluorination von Huang, Hui, Meegalla, Sanath K, Lanter, James C, Winters, Michael P, Zhao, Shuyuan, Littrell, James, Qi, Jenson, Rady, Brian, Lee, Paul S, Liu, Jianying, Martin, Tonya, Lam, Wing W, Xu, Fran, Lim, Heng Keang, Wilde, Thomas, Silva, Jose, Otieno, Monicah, Pocai, Alessandro, Player, Mark R

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Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors von Meegalla, Sanath K., Huang, Hui, Illig, Carl R., Parks, Daniel J., Chen, Jinsheng, Lee, Yu-Kai, Wilson, Kenneth J., Patel, Sharmila K., Cheung, Wing S., Lu, Tianbao, Kirchner, Thomas, Askari, Hossein B., Geisler, John, Patch, Raymond J., Gibbs, Alan C., Rady, Brian, Connelly, Margery, Player, Mark R.

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Use of Glucagon-Like Peptide-1 Agonists to Improve Islet Graft Performance von Wang, Yong, Qi, Meirigeng, McGarrigle, James J., Rady, Brian, Davis, Maureen E., Vaca, Pilar, Oberholzer, Jose

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The Effect of Light Intensity, Sensor Height, and Spectral Pre-Processing Methods When Using NIR Spectroscopy to Identify Different Allergen-Containing Powdered Foods von Rady, Ahmed, Fischer, Joel, Reeves, Stuart, Logan, Brian, Watson, Nicholas James

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Efficacy of Precocene I from Desmosstachya bipinnata as an Effective Bioactive Molecules against the Spodoptera litura Fab. and Its Impact on Eisenia fetida Savigny von Sundar, Narayanan Shyam, Karthi, Sengodan, Sivanesh, Haridoss, Stanley-Raja, Vethamonickam, Chanthini, Kanagaraj Muthu-Pandian, Ramasubramanian, Ramakrishnan, Ramkumar, Govindaraju, Ponsankar, Athirstam, Narayanan, Kilapavoor Raman, Vasantha-Srinivasan, Prabhakaran, Alkahtani, Jawaher, Alwahibi, Mona S., Hunter, Wayne Brian, Senthil-Nathan, Sengottayan, Patcharin, Krutmuang, Abdel-Megeed, Ahmed, Shawer, Rady, Ghaith, Aml

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Introduction of recovery position training to healthcare students von Fink, Brian N., Sexton, Martha, McKenzie, Nicole, Oberlander, James, Rady, Allison, Rega, Paul P.

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High-Level Variability in the ORF-K1 Membrane Protein Gene at the Left End of the Kaposi’s Sarcoma-Associated Herpesvirus Genome Defines Four Major Virus Subtypes and Multiple Vari... von Zong, J C, Ciufo, D M, Alcendor, D J, Wan, X, Nicholas, J, Browning, P J, Rady, P L, Tyring, S K, Orenstein, J M, Rabkin, C S, Su, I J, Powell, K F, Croxson, M, Foreman, K E, Nickoloff, B J, Alkan, S, Hayward, G S

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Interaction with the 5D3 Monoclonal Antibody Is Regulated by Intramolecular Rearrangements but Not by Covalent Dimer Formation of the Human ABCG2 Multidrug Transporter von Özvegy-Laczka, Csilla, Laczkó, Rozália, Hegedűs, Csilla, Litman, Thomas, Várady, György, Goda, Katalin, Hegedűs, Tamás, Dokholyan, Nikolay V., Sorrentino, Brian P., Váradi, András, Sarkadi, Balázs

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