Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex von Patel, Avinash B., Qing, Jinkang, Tam, Kelly H., Zaman, Sara, Luiso, Maria, Radhakrishnan, Ishwar, He, Yuan

Volltext

A Role for WDR5 in Integrating Threonine 11 Phosphorylation to Lysine 4 Methylation on Histone H3 during Androgen Signaling and in Prostate Cancer von Kim, Ji-Young, Banerjee, Taraswi, Vinckevicius, Aurimas, Luo, Qianyi, Parker, J. Brandon, Baker, Mairead R., Radhakrishnan, Ishwar, Wei, Jian-Jun, Barish, Grant D., Chakravarti, Debabrata

Volltext

Structural Basis for Multi-specificity of MRG Domains von Xie, Tao, Zmyslowski, Adam M., Zhang, Yongbo, Radhakrishnan, Ishwar

Volltext

Per-ARNT-Sim (PAS) Domains in Basic Helix-Loop-Helix (bHLH)-PAS Transcription Factors and Coactivators: Structures and Mechanisms von Daffern, Nicolas, Radhakrishnan, Ishwar

Volltext

Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex von Clark, Michael D, Ryan Marcum, Richard Graveline, Clarence W. Chan, Tao Xie, Zhonglei Chen, Yujia Ding, Yongbo Zhang, Alfonso Mondragón, Gregory David, Ishwar Radhakrishnan

Volltext

Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2 von Luo, Qianyi, Viste, Kristin, Urday-Zaa, Janny Concha, Kumar, Ganesan Senthil, Tsai, Wen-Wei, Talai, Afsaneh, Mayo, Kelly E., Montminy, Marc, Radhakrishnan, Ishwar

Volltext

A Novel Mechanism of Coactivator Recruitment by the Nurr1 Nuclear Receptor von Daffern, Nicolas, Radhakrishnan, Ishwar

Volltext

Sequence Requirements for Combinatorial Recognition of Histone H3 by the MRG15 and Pf1 Subunits of the Rpd3S/Sin3S Corepressor Complex von Kumar, Ganesan Senthil, Chang, William, Xie, Tao, Patel, Anand, Zhang, Yongbo, Wang, Gang Greg, David, Gregory, Radhakrishnan, Ishwar

Volltext

Inositol phosphates and core subunits of the Sin3L/Rpd3L histone deacetylase (HDAC) complex up-regulate deacetylase activity von Marcum, Ryan Dale, Radhakrishnan, Ishwar

Volltext

Solution Structure of a CUE-Ubiquitin Complex Reveals a Conserved Mode of Ubiquitin Binding von Kang, Richard S, Daniels, Cynthia M, Francis, Smitha A, Shih, Susan C, Salerno, William J, Hicke, Linda, Radhakrishnan, Ishwar

Volltext

The neuronal transcription factor Myt1L interacts via a conserved motif with the PAH1 domain of Sin3 to recruit the Sin3L/Rpd3L histone deacetylase complex von Marcum, Ryan Dale, Radhakrishnan, Ishwar

Volltext

A Threaded Loop Conformation Adopted by a Family of Peptoid Nonamers von Huang, Kai, Wu, Cindy W, Sanborn, Tracy J, Patch, James A, Kirshenbaum, Kent, Zuckermann, Ronald N, Barron, Annelise E, Radhakrishnan, Ishwar

Volltext

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions von Radhakrishnan, Ishwar, Pérez-Alvarado, Gabriela C, Parker, David, Dyson, H.Jane, Montminy, Marc R, Wright, Peter E

Volltext

Structural Basis for Monoubiquitin Recognition by the Ede1 UBA Domain von Swanson, Kurt A., Hicke, Linda, Radhakrishnan, Ishwar

Volltext

Histone acetylation and deacetylation – Mechanistic insights from structural biology von Patel, Avinash B., He, Yuan, Radhakrishnan, Ishwar

Volltext

Biochemical and Biophysical Characterization of Histone Deacetylase Recruitment to the Sin3L/Rpd3L Corepressor Complex von Marcum, Ryan, Radhakrishnan, Ishwar

Volltext

A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes von Marcum, Ryan Dale, Hsieh, Joseph, Giljen, Maksim, Justice, Emily, Daffern, Nicolas, Zhang, Yongbo, Radhakrishnan, Ishwar

Volltext

Solution Nuclear Magnetic Resonance Studies of the Ligand-Binding Domain of an Orphan Nuclear Receptor Reveal a Dynamic Helix in the Ligand-Binding Pocket von Daffern, Nicolas, Chen, Zhonglei, Zhang, Yongbo, Pick, Leslie, Radhakrishnan, Ishwar

Volltext

Solution NMR Studies of an Alternative Mode of Sin3 Engagement by the Sds3 Subunit in the Histone Deacetylase-Associated Sin3L/Rpd3L Corepressor Complex von Clark, Michael David, Zhang, Yongbo, Radhakrishnan, Ishwar

Volltext

Analysis of an Activator:Coactivator Complex Reveals an Essential Role for Secondary Structure in Transcriptional Activation von Parker, David, Jhala, Ulupi S, Radhakrishnan, Ishwar, Yaffe, Michael B, Reyes, Christine, Shulman, Andrew I, Cantley, Lewis C, Wright, Peter E, Montminy, Marc

Volltext