Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity von Lee, Cheryl Q. E., Kerouanton, Baptiste, Chothani, Sonia, Zhang, Shan, Chen, Ying, Mantri, Chinmay Kumar, Hock, Daniella Helena, Lim, Radiance, Nadkarni, Rhea, Huynh, Vinh Thang, Lim, Daryl, Chew, Wei Leong, Zhong, Franklin L., Stroud, David Arthur, Schafer, Sebastian, Tergaonkar, Vinay, St John, Ashley L., Rackham, Owen J. L., Ho, Lena

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Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis von Quah, Hong Sheng, Cao, Elaine Yiqun, Suteja, Lisda, Li, Constance H., Leong, Hui Sun, Chong, Fui Teen, Gupta, Shilpi, Arcinas, Camille, Ouyang, John F., Ang, Vivian, Celhar, Teja, Zhao, Yunqian, Tay, Hui Chen, Chan, Jerry, Takahashi, Takeshi, Tan, Daniel S. W., Biswas, Subhra K., Rackham, Owen J. L., Iyer, N. Gopalakrishna

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Differences in 5'untranslated regions highlight the importance of translational regulation of dosage sensitive genes von Wieder, Nechama, D'Souza, Elston N, Martin-Geary, Alexandra C, Lassen, Frederik H, Talbot-Martin, Jonathan, Fernandes, Maria, Chothani, Sonia P, Rackham, Owen J L, Schafer, Sebastian, Aspden, Julie L, MacArthur, Daniel G, Davies, Robert W, Whiffin, Nicola

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A predictive computational framework for direct reprogramming between human cell types von Rackham, Owen J L, Firas, Jaber, Fang, Hai, Oates, Matt E, Holmes, Melissa L, Knaupp, Anja S, Suzuki, Harukazu, Nefzger, Christian M, Daub, Carsten O, Shin, Jay W, Petretto, Enrico, Forrest, Alistair R R, Hayashizaki, Yoshihide, Polo, Jose M, Gough, Julian

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Transcriptional signature in microglia associated with Aβ plaque phagocytosis von Grubman, Alexandra, Choo, Xin Yi, Chew, Gabriel, Ouyang, John F., Sun, Guizhi, Croft, Nathan P., Rossello, Fernando J., Simmons, Rebecca, Buckberry, Sam, Landin, Dulce Vargas, Pflueger, Jahnvi, Vandekolk, Teresa H., Abay, Zehra, Zhou, Yichen, Liu, Xiaodong, Chen, Joseph, Larcombe, Michael, Haynes, John M., McLean, Catriona, Williams, Sarah, Chai, Siew Yeen, Wilson, Trevor, Lister, Ryan, Pouton, Colin W., Purcell, Anthony W., Rackham, Owen J. L., Petretto, Enrico, Polo, Jose M.

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Titin-truncating variants affect heart function in disease cohorts and the general population von Schafer, Sebastian, de Marvao, Antonio, Adami, Eleonora, Fiedler, Lorna R, Ng, Benjamin, Khin, Ester, Rackham, Owen J L, van Heesch, Sebastiaan, Pua, Chee J, Kui, Miao, Walsh, Roddy, Tayal, Upasana, Prasad, Sanjay K, Dawes, Timothy J W, Ko, Nicole S J, Sim, David, Chan, Laura L H, Chin, Calvin W L, Mazzarotto, Francesco, Barton, Paul J, Kreuchwig, Franziska, de Kleijn, Dominique P V, Totman, Teresa, Biffi, Carlo, Tee, Nicole, Rueckert, Daniel, Schneider, Valentin, Faber, Allison, Regitz-Zagrosek, Vera, Seidman, Jonathan G, Seidman, Christine E, Linke, Wolfgang A, Kovalik, Jean-Paul, O'Regan, Declan, Ware, James S, Hubner, Norbert, Cook, Stuart A

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Potassium channel dysfunction in human neuronal models of Angelman syndrome von Sun, Alfred Xuyang, Yuan, Qiang, Fukuda, Masahiro, Yu, Weonjin, Yan, Haidun, Lim, Grace Gui Yin, Nai, Mui Hoon, D'Agostino, Giuseppe Alessandro, Tran, Hoang-Dai, Itahana, Yoko, Wang, Danlei, Lokman, Hidayat, Itahana, Koji, Lim, Stephanie Wai Lin, Tang, Jiong, Chang, Ya Yin, Zhang, Menglan, Cook, Stuart A, Rackham, Owen J L, Lim, Chwee Teck, Tan, Eng King, Ng, Huck Hui, Lim, Kah Leong, Jiang, Yong-Hui, Je, Hyunsoo Shawn

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GeneSwitches: ordering gene expression and functional events in single-cell experiments von Cao, Elaine Y, Ouyang, John F, Rackham, Owen J L

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Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease von Johnson, Michael R, Shkura, Kirill, Langley, Sarah R, Delahaye-Duriez, Andree, Srivastava, Prashant, Hill, W David, Rackham, Owen J L, Davies, Gail, Harris, Sarah E, Moreno-Moral, Aida, Rotival, Maxime, Speed, Doug, Petrovski, Slavé, Katz, Anaïs, Hayward, Caroline, Porteous, David J, Smith, Blair H, Padmanabhan, Sandosh, Hocking, Lynne J, Starr, John M, Liewald, David C, Visconti, Alessia, Falchi, Mario, Bottolo, Leonardo, Rossetti, Tiziana, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Grote, Alexander, Helmstaedter, Christoph, Becker, Albert J, Kaminski, Rafal M, Deary, Ian J, Petretto, Enrico

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A novel network pharmacology approach for leukaemia differentiation therapy using Mogrify von Lee, Lin Ming, Christodoulou, Eleni G., Shyamsunder, Pavithra, Chen, Bei Jun, Lee, Kian Leong, Fung, Tsz Kan, So, Chi Wai Eric, Wong, Gee Chuan, Petretto, Enrico, Rackham, Owen J. L., Tiong Ong, S.

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Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential von Nefzger, Christian M., Jardé, Thierry, Srivastava, Akanksha, Schroeder, Jan, Rossello, Fernando J., Horvay, Katja, Prasko, Mirsada, Paynter, Jacob M., Chen, Joseph, Weng, Chen-Fang, Sun, Yu B. Y., Liu, Xiaodong, Chan, Eva, Deshpande, Nikita, Chen, Xiaoli, Li, Y. Jinhua, Pflueger, Jahnvi, Engel, Rebekah M., Knaupp, Anja S., Tsyganov, Kirill, Nilsson, Susan K., Lister, Ryan, Rackham, Owen J. L., Abud, Helen E., Polo, Jose M.

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SUPERFAMILY 1.75 including a domain-centric gene ontology method von de Lima Morais, David A, Fang, Hai, Rackham, Owen J.L, Wilson, Derek, Pethica, Ralph, Chothia, Cyrus, Gough, Julian

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EvoTol: a protein-sequence based evolutionary intolerance framework for disease-gene prioritization von Rackham, Owen J L, Shihab, Hashem A, Johnson, Michael R, Petretto, Enrico

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A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation von Grubman, Alexandra, Chew, Gabriel, Ouyang, John F., Sun, Guizhi, Choo, Xin Yi, McLean, Catriona, Simmons, Rebecca K., Buckberry, Sam, Vargas-Landin, Dulce B., Poppe, Daniel, Pflueger, Jahnvi, Lister, Ryan, Rackham, Owen J. L., Petretto, Enrico, Polo, Jose M.

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Modelling human blastocysts by reprogramming fibroblasts into iBlastoids von Liu, Xiaodong, Tan, Jia Ping, Schröder, Jan, Aberkane, Asma, Ouyang, John F., Mohenska, Monika, Lim, Sue Mei, Sun, Yu B. Y., Chen, Joseph, Sun, Guizhi, Zhou, Yichen, Poppe, Daniel, Lister, Ryan, Clark, Amander T., Rackham, Owen J. L., Zenker, Jennifer, Polo, Jose M.

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deltaTE: Detection of Translationally Regulated Genes by Integrative Analysis of Ribo‐seq and RNA‐seq Data von Chothani, Sonia, Adami, Eleonora, Ouyang, John F., Viswanathan, Sivakumar, Hubner, Norbert, Cook, Stuart A., Schafer, Sebastian, Rackham, Owen J. L.

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An atlas of human long non-coding RNAs with accurate 5′ ends von Hon, Chung-Chau, Ramilowski, Jordan A., Harshbarger, Jayson, Bertin, Nicolas, Rackham, Owen J. L., Gough, Julian, Denisenko, Elena, Schmeier, Sebastian, Poulsen, Thomas M., Severin, Jessica, Lizio, Marina, Kawaji, Hideya, Kasukawa, Takeya, Itoh, Masayoshi, Burroughs, A. Maxwell, Noma, Shohei, Djebali, Sarah, Alam, Tanvir, Medvedeva, Yulia A., Testa, Alison C., Lipovich, Leonard, Yip, Chi-Wai, Abugessaisa, Imad, Mendez, Mickaël, Hasegawa, Akira, Tang, Dave, Lassmann, Timo, Heutink, Peter, Babina, Magda, Wells, Christine A., Kojima, Soichi, Nakamura, Yukio, Suzuki, Harukazu, Daub, Carsten O., de Hoon, Michiel J. L., Arner, Erik, Hayashizaki, Yoshihide, Carninci, Piero, Forrest, Alistair R. R.

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ShinyCell: simple and sharable visualization of single-cell gene expression data von Ouyang, John F, Kamaraj, Uma S, Cao, Elaine Y, Rackham, Owen J L

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Evaluating Capture Sequence Performance for Single-Cell CRISPR Activation Experiments von Choo, Xin Yi, Lim, Yu Ming, Katwadi, Khairunnisa, Yap, Lynn, Tryggvason, Karl, Sun, Alfred Xuyang, Li, Shang, Handoko, Lusy, Ouyang, John F, Rackham, Owen J. L

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Let it RE:IN: integrating experimental observations to predict pluripotency network behaviour von Rackham, Owen JL, Polo, Jose M

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