Phase II randomized trial of weekly and every-3-week ixabepilone in metastatic breast cancer patients von Smith, John W., Vukelja, Svetislava, Rabe, Amy, Wentworth-Hartung, Nicole, Koutrelakos, Nicholas, Shao, Spencer H., Whittaker, Thomas, Wang, Yunfei, Asmar, Lina, McDowell, Diane Opatt, Mukhopadhyay, Pralay, O’Shaughnessy, Joyce

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Freshwater in the Arctic Ocean 2010–2019 von Solomon, Amy, Heuzé, Céline, Rabe, Benjamin, Bacon, Sheldon, Bertino, Laurent, Heimbach, Patrick, Inoue, Jun, Iovino, Doroteaciro, Mottram, Ruth, Zhang, Xiangdong, Aksenov, Yevgeny, McAdam, Ronan, Nguyen, An, Raj, Roshin P, Tang, Han

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Evaluation of a PEGylated Fibroblast Growth Factor 21 Variant Using Novel Preclinical Magnetic Resonance Imaging and Magnetic Resonance Elastography in a Mouse Model of Nonalcoholi... von Tang, Haiying, Li, Jiahui, Zinker, Bradley, Boehm, Stephanie, Mauer, Amy, Rex‐Rabe, Sandra, Glaser, Kevin J., Fronheiser, Matthew, Bradstreet, Thomas, Nakao, Yasuhiko, Petrone, Thomas, Pena, Adrienne, Villano, MacKenzie, Chow, Patrick, Malhi, Harmeet, Charles, Edgar D., Hayes, Wendy, Ehman, Richard L., Du, Shuyan, Yin, Meng

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Implementing digital respiratory technologies for people with respiratory conditions: A protocol for a scoping review von Hui, Chi Yan, Condon, Kathleena, Kolekar, Shailesh, Roberts, Nicola, Sreter, Katherina Bernadette, Simons, Sami O, Figueiredo, Carlos, McKeough, Zoe, Salim, Hani, Gawlik-Lipinski, Aleksandra, Gonsard, Apolline, Önal Aral, Ayşe, Vanoverschelde, Anna, Armstrong, Matthew, Kohlbrenner, Dario, Paixão, Cátia, Stafler, Patrick, Papadopoulou, Efthymia, Rabe, Adrian Paul, Mohammad, Milan, Bouloukaki, Izolde, Quach, Shirley, Chaabouni, Malek, Kaltsakas, Georgios, Loveys, Kate, Reier-Nilsen, Tonje, Sunjaya, Anthony Paulo, Robinson, Paul, Pinnock, Hilary, Chan, Amy Hai Yan

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Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia von Giacopelli, Brian, Zhao, Qiuhong, Ruppert, Amy S., Agyeman, Akwasi, Weigel, Christoph, Wu, Yue-Zhong, Gerber, Madelyn M., Rabe, Kari G., Larson, Melissa C., Lu, Junyan, Blachly, James S., Rogers, Kerry A., Wierda, William G., Brown, Jennifer R., Rai, Kanti R., Keating, Michael, Rassenti, Laura Z., Kipps, Thomas J., Zenz, Thorsten, Shanafelt, Tait D., Kay, Neil E., Abruzzo, Lynne V., Coombes, Kevin R., Woyach, Jennifer A., Byrd, John C., Oakes, Christopher C.

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Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease von Ikari, Jun, Nelson, Amy J, Obaid, Jannah, Giron-Martinez, Alvaro, Ikari, Kumiko, Makino, Fumihiko, Iwasawa, Shunichiro, Gunji, Yoko, Farid, Maha, Wang, Xingqi, Basma, Hesham, Demeo, Dawn, Feghali-Bostwick, Carol, Holz, Olaf, Rabe, Klaus, Liu, Xiangde, Rennard, Stephen I

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A Randomized Controlled Trial of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) to Improve Serious Mental Illness Outcomes in a Community Setting von Harvey, Allison G., Dong, Lu, Hein, Kerrie, Yu, Stephanie H., Martinez, Armando J., Gumport, Nicole B., Smith, Freddie L., Chapman, Aaron, Lisman, Michael, Mirzadegan, Isaac A., Mullin, Alice C., Fine, Eve, Dolsen, Emily A., Gasperetti, Caitlin E., Bukosky, Jorin, Alvarado-Martinez, Cynthia G., Kilbourne, Amy M., Rabe-Hesketh, Sophia, Buysse, Daniel J.

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First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy von Anton, Peter A, Saunders, Terry, Elliott, Julie, Khanukhova, Elena, Dennis, Robert, Adler, Amy, Cortina, Galen, Tanner, Karen, Boscardin, John, Cumberland, William G, Zhou, Ying, Ventuneac, Ana, Carballo-Diéguez, Alex, Rabe, Lorna, McCormick, Timothy, Gabelnick, Henry, Mauck, Christine, McGowan, Ian

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Multi-institutional Assessment of Pathologist Scoring HER2 Immunohistochemistry von Robbins, Charles J, Fernandez, Aileen I, Han, Gang, Wong, Serena, Harigopal, Malini, Podoll, Mirna, Singh, Kamaljeet, Ly, Amy, Kuba, M Gabriela, Wen, Hannah, Sanders, Mary Ann, Brock, Jane, Wei, Shi, Fadare, Oluwole, Hanley, Krisztina, Jorns, Julie, Snir, Olivia L, Yoon, Esther, Rabe, Kim, Soong, T Rinda, Reisenbichler, Emily S, Rimm, David L

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Polar Fresh Water in a Changing Global Climate: Linking Arctic and Southern Ocean Processes von Rabe, Benjamin, Martin, Torge, Solomon, Amy, Assmann, Karen M., Biddle, Louise C., Haine, Thomas, Hattermann, Tore, Haumann, F. Alexander, Jahn, Alexandra, Karpouzoglou, Theodoros, Laukert, Georgi, Garabato, Alberto Naveira, Rosenblum, Erica, Sikes, Elisabeth, Yin, Liping, Zhang, Xiangdong

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639 THE REGARD STUDY: A PROSPECTIVE STUDY OF RISK OF PANCREATIC DUCTAL ADENOCARCINOMA IN GLYCEMICALLY DEFINED NEW-ONSET DIABETES ASCERTAINED BY ALGORITHM BASED PASSIVE SURVEILLANCE... von Chari, Suresh, Wu, Bechien U., Qian, Lu, Lustigova, Eva, Chen, Qiaoling, Van Den Eeden, Stephen K., Leimpeter, Amethyst D., Fisher, William E., Alexander, Ashley S., Wood, Amy, Valenta, John, Vege, Santhi Swaroop, Carlson, Erin E., Rabe, Kari G., Kenner, Barbara, Yosuf, Nadia, Lopez, Camden, Zhao, Ying-Qi, Matrisian, Lynn, Maitra, Anirban, Rinaudo, Jo Ann, Feng, Ziding

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Investigation of Heartland Virus Disease Throughout the United States, 2013–2017 von Staples, J Erin, Pastula, Daniel M, Panella, Amanda J, Rabe, Ingrid B, Kosoy, Olga I, Walker, William L, Velez, Jason O, Lambert, Amy J, Fischer, Marc

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Safe and Sustained Vaginal Delivery of Pyrimidinedione HIV-1 Inhibitors from Polyurethane Intravaginal Rings von JOHNSON, Todd J, SRINIVASAN, Priya, BUCKHEIT, Robert, SMITH, James, KISER, Patrick F, ALBRIGHT, Theodore H, WATSON-BUCKHEIT, Karen, RABE, Lorna, MARTIN, Amy, PAU, Chou-Pong, MICHAEL HENDRY, R, OTTEN, Ron, MCNICHOLL, Janet

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CLL-081 Impact of Multi-Hit vs Single-Hit TP53 Mutations in Chronic Lymphocytic Leukemia von Hwang, Steven, Wang, Yucai, Rabe, Kari, Williams-Watley, Marquise, Hampel, Paul, Kenderian, Saad, Muchtar, Eli, Koehler, Amber, Behnken, Amy, Kay, Neil, Parikh, Sameer, He, Rong, Ding, Wei

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POSTER: CLL-081 Impact of Multi-Hit vs Single-Hit TP53 Mutations in Chronic Lymphocytic Leukemia von Hwang, Steven, Wang, Yucai, Rabe, Kari, Williams-Watley, Marquise, Hampel, Paul, Kenderian, Saad, Muchtar, Eli, Koehler, Amber, Behnken, Amy, Kay, Neil, Parikh, Sameer, He, Rong, Ding, Wei

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Treatment Patterns and Outcomes of Patients with Chronic Lymphocytic Leukemia with TP53 Mutations von Hwang, Steven R, Wang, Yucai, Rabe, Kari G, He, Rong, Kenderian, Saad S., Muchtar, Eli, Hampel, Paul J., Kay, Neil E., Call, Timothy G., Koehler, Amber, Behnken, Amy L, Leis, Jose F., Braggio, Esteban, Shi, Min, Viswanatha, David S., Van Dyke, Daniel L., Slager, Susan L., Parikh, Sameer A., Ding, Wei

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MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps von Wang, Liang, Baudhuin, Linnea M., Boardman, Lisa A., Steenblock, Kelle J., Petersen, Gloria M., Halling, Kevin C., French, Amy J., Johnson, Ruth A., Burgart, Lawrence J., Rabe, Kari, Lindor, Noralane M., Thibodeau, Stephen N.

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Abstract P1-02-02: Examination of low Her2 expression in breast cancer von Fernandez, Aileen I, Liu, Matthew, Bellizzi, Andrew, Brock, Jane, Fadare, Oluwole, Hanley, Krisztina, Harigopal, Malini, Jorns, Julie M., Kuba, M. Gabriela, Ly, Amy, Podoll, Mirna, Rabe, Kimmie, Sanders, Mary Ann, Singh, Kamaljeet, Snir, Olivia L, Soong, Rinda, Wei, Shi, Wen, Hannah, Wong, Serena, Yoon, Esther, Pusztai, Lajos, Reisenbichler, Emily, Rimm, David L.

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Abstract PS4-09: Pathologic features of the inter-regimen biopsy predict response to neoadjuvant therapy in the I-SPY 2 TRIAL von Carter, Jodi M, Klein, Molly E, Venters, Sara J, Rabe, Kimmie, Ocal, I Tolgay, Singh, Kamaljeet, Wolf, Denise M, Sahoo, Sunati, Harada, Shuko, Khazai, Laila, Harigopal, Malini, Borowsky, Alexander D, Krings, Gregor, Balassanian, Ronald, Chen, Yunn-Yi, Cole, Kimberley, Shad, Sonal, Delson, Amy, Brown-Swigart, Lamorna, Esserman, Laura, van ‘t Veer, Laura, Symmans, W Fraser

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Abstract PS4-10: Serial MRI and pathology combined to select candidates for therapy de-escalation in the I-SPY 2 TRIAL von Venters, Sara J, Li, Wen, Wolf, Denise M, Carter, Jodi M, Klein, Molly E, Singh, Kamaljeet, Rabe, Kimmie, Ocal, I Tolgay, Newitt, David, Yau, Christina, Onishi, Natsuko, Gibbs, Jessica, Sahoo, Sunati, Harada, Shuko, Khazai, Laila, Harigopal, Malini, Borowsky, Alexander D, Krings, Gregor, Balassanian, Ronald, Chen, Yunn-Yi, Cole, Kimberley, Shad, Sonal, LeStage, Barbara, Delson, Amy, Finestone, Sandra, Brown-Swigart, Lamorna, Esserman, Laura, van ‘t Veer, Laura, Symmans, W Fraser, Hylton, Nola M

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