Impact of HLA type, age and chronic viral infection on peripheral T-cell receptor sharing between unrelated individuals von Johnson, Sarah A, Seale, Spencer L, Gittelman, Rachel M, Rytlewski, Julie A, Robins, Harlan S, Fields, Paul A

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Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses von Lavin, Yonit, Kobayashi, Soma, Leader, Andrew, Amir, El-ad David, Elefant, Naama, Bigenwald, Camille, Remark, Romain, Sweeney, Robert, Becker, Christian D., Levine, Jacob H., Meinhof, Klaus, Chow, Andrew, Kim-Shulze, Seunghee, Wolf, Andrea, Medaglia, Chiara, Li, Hanjie, Rytlewski, Julie A., Emerson, Ryan O., Solovyov, Alexander, Greenbaum, Benjamin D., Sanders, Catherine, Vignali, Marissa, Beasley, Mary Beth, Flores, Raja, Gnjatic, Sacha, Pe’er, Dana, Rahman, Adeeb, Amit, Ido, Merad, Miriam

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TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma von Brown, Jessie A., Yonekubo, Yoshiya, Hanson, Nicole, Sastre-Perona, Ana, Basin, Alice, Rytlewski, Julie A., Dolgalev, Igor, Meehan, Shane, Tsirigos, Aristotelis, Beronja, Slobodan, Schober, Markus

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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial von Wrangle, John M, Velcheti, Vamsidhar, Patel, Manish R, Garrett-Mayer, Elizabeth, Hill, Elizabeth G, Ravenel, James G, Miller, Jeffrey S, Farhad, Mohammad, Anderton, Kate, Lindsey, Kathryn, Taffaro-Neskey, Michele, Sherman, Carol, Suriano, Samantha, Swiderska-Syn, Marzena, Sion, Amy, Harris, Joni, Edwards, Andie R, Rytlewski, Julie A, Sanders, Catherine M, Yusko, Erik C, Robinson, Mark D, Krieg, Carsten, Redmond, William L, Egan, Jack O, Rhode, Peter R, Jeng, Emily K, Rock, Amy D, Wong, Hing C, Rubinstein, Mark P

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Correction of aberrant growth preserves tissue homeostasis von Brown, Samara, Pineda, Cristiana M., Xin, Tianchi, Boucher, Jonathan, Suozzi, Kathleen C., Park, Sangbum, Matte-Martone, Catherine, Gonzalez, David G., Rytlewski, Julie, Beronja, Slobodan, Greco, Valentina

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The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma von Agdashian, David, ElGindi, Mei, Xie, Changqing, Sandhu, Milan, Pratt, Drew, Kleiner, David E., Figg, William D., Rytlewski, Julie A., Sanders, Catherine, Yusko, Erik C., Wood, Bradford, Venzon, David, Brar, Gagandeep, Duffy, Austin G., Greten, Tim F., Korangy, Firouzeh

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Model to improve specificity for identification of clinically-relevant expanded T cells in peripheral blood von Rytlewski, Julie, Deng, Shibing, Xie, Tao, Davis, Craig, Robins, Harlan, Yusko, Erik, Bienkowska, Jadwiga

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Fibrin-based 3D matrices induce angiogenic behavior of adipose-derived stem cells von Chung, Eunna, Rytlewski, Julie A., Merchant, Arjun G., Dhada, Kabir S., Lewis, Evan W., Suggs, Laura J.

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T cell receptor repertoire features associated with survival in immunotherapy-treated pancreatic ductal adenocarcinoma von Hopkins, Alexander C, Yarchoan, Mark, Durham, Jennifer N, Yusko, Erik C, Rytlewski, Julie A, Robins, Harlan S, Laheru, Daniel A, Le, Dung T, Lutz, Eric R, Jaffee, Elizabeth M

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The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients von Khunger, Arjun, Rytlewski, Julie A., Fields, Paul, Yusko, Erik C., Tarhini, Ahmad A.

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CDK4/6 inhibition enhances antitumor efficacy of chemotherapy and immune checkpoint inhibitor combinations in preclinical models and enhances T-cell activation in patients with SCL... von Lai, Anne Y, Sorrentino, Jessica A, Dragnev, Konstantin H, Weiss, Jared M, Owonikoko, Taofeek K, Rytlewski, Julie A, Hood, Jill, Yang, Zhao, Malik, Rajesh K, Strum, Jay C, Roberts, Patrick J

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Neoadjuvant ipilimumab (3 mg/kg or 10 mg/kg) and high dose IFN-α2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire von Tarhini, Ahmad, Lin, Yan, Lin, Huang, Rahman, Zahra, Vallabhaneni, Priyanka, Mendiratta, Prateek, Pingpank, James F, Holtzman, Matthew P, Yusko, Erik C, Rytlewski, Julie A, Rao, Uma N M, Ferris, Robert L, Kirkwood, John M

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The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity von Palakurthi, Sangeetha, Kuraguchi, Mari, Zacharek, Sima J, Zudaire, Enrique, Huang, Wei, Bonal, Dennis M, Liu, Jeffrey, Dhaneshwar, Abha, DePeaux, Kristin, Gowaski, Martha R, Bailey, Dyane, Regan, Samuel N, Ivanova, Elena, Ferrante, Catherine, English, Jessie M, Khosla, Aditya, Beck, Andrew H, Rytlewski, Julie A, Sanders, Catherine, Laquerre, Sylvie, Bittinger, Mark A, Kirschmeier, Paul T, Packman, Kathryn, Janne, Pasi A, Moy, Christopher, Wong, Kwok-Kin, Verona, Raluca I, Lorenzi, Matthew V

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CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes von Schroeder, Brett A, LaFranzo, Natalie A, LaFleur, Bonnie J, Gittelman, Rachel M, Vignali, Marissa, Zhang, Shihong, Flanagan, Kevin C, Rytlewski, Julie, Riolobos, Laura, Schulte, Brian C, Kim, Teresa S, Chen, Eleanor, Smythe, Kimberly S, Wagner, Michael J, Mantilla, Jose G, Campbell, Jean S, Pierce, Robert H, Jones, Robin L, Cranmer, Lee D, Pollack, Seth M

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P809: BASELINE CHARACTERISTICS IDENTIFYING PATIENTS WITH MULTIPLE MYELOMA TREATED WITH IDECABTAGENE VICELEUCEL (IDE‐CEL; BB2121) WHO ARE AT RISK FOR SEVERE/REFRACTORY INFLAMMATORY... von Mashadi‐Hossein, Afshin, Rytlewski, Julie, Shamsuzzaman, MD, Basudhar, Debashree, Takhar, Mandeep, Kostic, Ana, Campbell, Timothy B., Manier, Salomon, Lin, Yi, Martin, Nathan

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Mechanisms of tubulogenesis and endothelial phenotype expression by MSCs von Rytlewski, Julie A., Alejandra Aldon, M., Lewis, Evan W., Suggs, Laura J.

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449 Concurrent ibrutinib enhances T cell function in patients with chronic lymphocytic leukemia (CLL) treated with lisocabtagene maraleucel (liso-cel), a chimeric antigen receptor... von Thorpe, Jerill, Rytlewski, Julie, Gillenwater, Heidi, Ogasawara, Ken, Kim, Yeonhee, Shpektor, Diana, Papp, Eniko, Peiser, Leanne

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Alloreactive T Cell Receptor Diversity against Structurally Similar or Dissimilar HLA-DP Antigens Assessed by Deep Sequencing von Arrieta-Bolaños, Esteban, Crivello, Pietro, Metzing, Maximilian, Meurer, Thuja, Ahci, Müberra, Rytlewski, Julie, Vignali, Marissa, Yusko, Erik, van Balen, Peter, Horn, Peter A, Falkenburg, J H Frederik, Fleischhauer, Katharina

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Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma von Cloughesy, Timothy F., Mochizuki, Aaron Y., Orpilla, Joey R., Hugo, Willy, Lee, Alexander H., Davidson, Tom B., Wang, Anthony C., Ellingson, Benjamin M., Rytlewski, Julie A., Sanders, Catherine M., Kawaguchi, Eric S., Du, Lin, Li, Gang, Yong, William H., Gaffey, Sarah C., Cohen, Adam L., Mellinghoff, Ingo K., Lee, Eudocia Q., Reardon, David A., O’Brien, Barbara J., Butowski, Nicholas A., Nghiemphu, Phioanh L., Clarke, Jennifer L., Arrillaga-Romany, Isabel C., Colman, Howard, Kaley, Thomas J., de Groot, John F., Liau, Linda M., Wen, Patrick Y., Prins, Robert M.

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Three-Dimensional Image Quantification as a New Morphometry Method for Tissue Engineering von Rytlewski, Julie A., Geuss, Laura R., Anyaeji, Chinedu I., Lewis, Evan W., Suggs, Laura J.

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