Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement von Zhao, Wei, Wurz, Ryan P, Peters, Jonas C, Fu, Gregory C

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Chiral Dialkylaminopyridine Catalysts in Asymmetric Synthesis von Wurz, Ryan P

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Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation von Wurz, Ryan P., Rui, Huan, Dellamaggiore, Ken, Ghimire-Rijal, Sudipa, Choi, Kaylee, Smither, Kate, Amegadzie, Albert, Chen, Ning, Li, Xiaofen, Banerjee, Abhisek, Chen, Qing, Mohl, Dane, Vaish, Amit

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Targeted Degradation of MDM2 as a New Approach to Improve the Efficacy of MDM2-p53 Inhibitors von Wurz, Ryan P, Cee, Victor J

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A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation von Wurz, Ryan P, Dellamaggiore, Ken, Dou, Hannah, Javier, Noelle, Lo, Mei-Chu, McCarter, John D, Mohl, Dane, Sastri, Christine, Lipford, J. Russell, Cee, Victor J

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Doubly Activated Cyclopropanes as Synthetic Precursors for the Preparation of 4-Nitro- and 4-Cyano-dihydropyrroles and Pyrroles von Wurz, Ryan P, Charette, André B

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Catalytic Asymmetric Synthesis of Piperidine Derivatives through the [4 + 2] Annulation of Imines with Allenes von Wurz, Ryan P, Fu, Gregory C

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Structural Elucidation and Absolute Stereochemistry for Pharma Compounds Using MicroED von de Moraes, Lygia Silva, Burch, Jessica E., Delgadillo, David A., Rodriguez, Isabel Hernandez, Mai, Huanghao, Smith, Austin G., Caille, Seb, Walker, Shawn D., Wurz, Ryan P., Cee, Victor J., Rodriguez, Jose A., Gostovic, Dan, Quasdorf, Kyle, Nelson, Hosea M.

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TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation von Ou, Yi-Hung, Torres, Michael, Ram, Rosalyn, Formstecher, Etienne, Roland, Christina, Cheng, Tzuling, Brekken, Rolf, Wurz, Ryan, Tasker, Andrew, Polverino, Tony, Tan, Seng-Lai, White, Michael A.

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Discovery of [1,2,4]Triazolo[1,5‑a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists von Nakajima, Ryota, Oono, Hiroyuki, Sugiyama, Sakae, Matsueda, Yohei, Ida, Tomohide, Kakuda, Shinji, Hirata, Jun, Baba, Atsushi, Makino, Akito, Matsuyama, Ryo, White, Ryan D, Wurz, Ryan Ρ, Shin, Youngsook, Min, Xiaoshan, Guzman-Perez, Angel, Wang, Zhulun, Symons, Antony, Singh, Sanjay K, Mothe, Srinivasa Reddy, Belyakov, Sergei, Chakrabarti, Anjan, Shuto, Satoshi

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Pyridin-2-one Synthesis Using Ester Enolates and Aryl Aminoaldehydes and Ketones von Apsunde, Tushar, Wurz, Ryan P

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Discovery of (R)‑8-(6-Methyl-4-oxo-1,4,5,6-tetrahydro­pyrrolo[3,4‑b]­pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)­amino)­quinazolin-4(3H)‑one, a Potent and Selecti... von Wang, Hui-Ling, Andrews, Kristin L, Booker, Shon K, Canon, Jude, Cee, Victor J, Chavez, Frank, Chen, Yuping, Eastwood, Heather, Guerrero, Nadia, Herberich, Brad, Hickman, Dean, Lanman, Brian A, Laszlo, Jimmy, Lee, Matthew R, Lipford, J. Russell, Mattson, Bethany, Mohr, Christopher, Nguyen, Yen, Norman, Mark H, Pettus, Liping H, Powers, David, Reed, Anthony B, Rex, Karen, Sastri, Christine, Tamayo, Nuria, Wang, Paul, Winston, Jeffrey T, Wu, Bin, Wu, Qiong, Wu, Tian, Wurz, Ryan P, Xu, Yang, Zhou, Yihong, Tasker, Andrew S

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Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors von Pettus, Liping H, Andrews, Kristin L, Booker, Shon K, Chen, Jie, Cee, Victor J, Chavez, Frank, Chen, Yuping, Eastwood, Heather, Guerrero, Nadia, Herberich, Bradley, Hickman, Dean, Lanman, Brian A, Laszlo, Jimmy, Lee, Matthew R, Lipford, J. Russell, Mattson, Bethany, Mohr, Christopher, Nguyen, Yen, Norman, Mark H, Powers, David, Reed, Anthony B, Rex, Karen, Sastri, Christine, Tamayo, Nuria, Wang, Paul, Winston, Jeffrey T, Wu, Bin, Wu, Tian, Wurz, Ryan P, Xu, Yang, Zhou, Yihong, Tasker, Andrew S, Wang, Hui-Ling

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An Expedient and Practical Method for the Synthesis of a Diverse Series of Cyclopropane α-Amino Acids and Amines von Wurz, Ryan P, Charette, André B

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Structure-Based Design of a Novel Series of Potent, Selective Inhibitors of the Class I Phosphatidylinositol 3-Kinases von Smith, Adrian L, D’Angelo, Noel D, Bo, Yunxin Y, Booker, Shon K, Cee, Victor J, Herberich, Brad, Hong, Fang-Tsao, Jackson, Claire L. M, Lanman, Brian A, Liu, Longbin, Nishimura, Nobuko, Pettus, Liping H, Reed, Anthony B, Tadesse, Seifu, Tamayo, Nuria A, Wurz, Ryan P, Yang, Kevin, Andrews, Kristin L, Whittington, Douglas A, McCarter, John D, Miguel, Tisha San, Zalameda, Leeanne, Jiang, Jian, Subramanian, Raju, Mullady, Erin L, Caenepeel, Sean, Freeman, Daniel J, Wang, Ling, Zhang, Nancy, Wu, Tian, Hughes, Paul E, Norman, Mark H

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Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors von Wurz, Ryan P., Sastri, Christine, D’Amico, Derin C., Herberich, Brad, Jackson, Claire L.M., Pettus, Liping H., Tasker, Andrew S., Wu, Bin, Guerrero, Nadia, Lipford, J. Russell, Winston, Jeffrey T., Yang, Yajing, Wang, Paul, Nguyen, Yen, Andrews, Kristin L., Huang, Xin, Lee, Matthew R., Mohr, Christopher, Zhang, J.D., Reid, Darren L., Xu, Yang, Zhou, Yihong, Wang, Hui-Ling

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Transition Metal-Catalyzed Cyclopropanation of Alkenes in Water:  Catalyst Efficiency and in Situ Generation of the Diazo Reagent von Wurz, Ryan P, Charette, André B

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Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors von Wu, Bin, Wang, Hui-Ling, Cee, Victor J., Lanman, Brian A., Nixey, Thomas, Pettus, Liping, Reed, Anthony B., Wurz, Ryan P., Guerrero, Nadia, Sastri, Christine, Winston, Jeff, Lipford, J. Russell, Lee, Matthew R., Mohr, Christopher, Andrews, Kristin L., Tasker, Andrew S.

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Synthesis and Resolution of Planar-Chiral Derivatives of 4-(Dimethylamino)pyridine von Wurz, Ryan P., Lee, Elaine C., Ruble, J. Craig, Fu, Gregory C.

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Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold von Herberich, Brad, Cao, Guo-Qiang, Chakrabarti, Partha P, Falsey, James R, Pettus, Liping, Rzasa, Robert M, Reed, Anthony B, Reichelt, Andreas, Sham, Kelvin, Thaman, Maya, Wurz, Ryan P, Xu, Shimin, Zhang, Dawei, Hsieh, Faye, Lee, Matthew R, Syed, Rashid, Li, Vivian, Grosfeld, David, Plant, Matthew H, Henkle, Bradley, Sherman, Lisa, Middleton, Scot, Wong, Lu Min, Tasker, Andrew S

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