Binding of the anticancer drug ZD1694 to E. coli thymidylate synthase: assessing specificity and affinity von Rutenber, Earl E, Stroud, Robert M

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Structure of a non-peptide inhibitor complexed with HIV-1 protease. Developing a cycle of structure-based drug design von RUTENBER, E, FAUMAN, E. B, ROSE, J. R, CRAIK, C. S, STROUD, R. M, KEENAN, R. J, FONG, S, FURTH, P. S, ORTIZ DE MONTELLANO, P. R, MENG, E, KUNTZ, I. D, DECAMP, D. L, SALTO, R

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Amino-terminal Domain Stability Mediates Apolipoprotein E Aggregation into Neurotoxic Fibrils von Hatters, Danny M., Zhong, Ning, Rutenber, Earl, Weisgraber, Karl H.

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An Essential Role for Water in an Enzyme Reaction Mechanism:  The Crystal Structure of the Thymidylate Synthase Mutant E58Q von Sage, Carleton R, Rutenber, Earl E, Stout, Thomas J, Stroud, Robert M

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The three-dimensional structure of ricin at 2.8 A von Montfort, W., Villafranca, J.E., Monzingo, A.F., Ernst, S.R., Katzin, B., Rutenber, E., Xuong, N.H., Hamlin, R., Robertus, J.D.

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Water-mediated substrate/product discrimination : the product complex of thymidylate synthase at 1.83 Å von FAUMAN, E. B, RUTENBER, E. E, MALEY, G. F, MALEY, F, STROUD, R. M

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Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer von Reyes, Christopher L., Sage, Carleton R., Rutenber, Earl E., Nissen, Robert M., Finer-Moore, Janet S., Stroud, Robert M.

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A new class of HIV-1 protease inhibitor: The crystallographic structure, inhibition and chemical synthesis of an aminimide peptide isostere von Rutenber, Earl E., McPhee, Fiona, Kaplan, Alan P., Gallion, Steven L., Hogan, Joseph C., Craik, Charles S., Stroud, Robert M.

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The discovery, characterization and crystallographically determined binding mode of an FMOC-containing inhibitor of HIV-1 protease von Rutenber, Earl E, De Voss, James J, Hoffman, Lucas, Stroud, Robert M, Lee, Kwan H, Alvarez, Juan, McPhee, Fiona, Craik, Charles, Ortiz de Montellano, Paul R

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Structure of ricin B-chain at 2.5 Å resolution von Rutenber, Earl, Robertus, Jon D.

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Crystallographic refinement of ricin to 2.5 Å von Rutenber, Earl, Katzin, Betsy J., Ernst, Stephen, Collins, Edward J., Mlsna, Debra, Ready, Michael P., Robertus, Jon D.

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Structure and evolution of ricin B chain von Rutenber, E, Ready, M, Robertus, J.D

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Water-mediated substrate/product discrimination: The product complex of thymidylate synthase at 1.83 .ANG von Fauman, Eric B, Rutenber, Earl E, Maley, Gladys F, Maley, Frank, Stroud, Robert M

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Structure of ricin B-chain at 2.5 Angstroms resolution von Rutenber, E, Robertus, J D

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Short-circuiting a water-mediated enzyme reaction von Sage, C. R., Rutenber, E. E., Stout, T. J., Stroud, R. M.

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Crystallographic refinement of ricin to 2.5 angstrom von Rutenber, E, Katzin, B J, Ernst, S, Collins, E J, Mlsna, D, Ready, M P, Robertus, J D

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The three-dimensional structure of ricin at 2.8 angstrom von Montfort, W, Villafranca, JE, Monzingo, A F, Ernst, SR, Katzin, B, Rutenber, E, Xuong, N H, Hamlin, R, Robertus, J D

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