In vivo genome editing of the albumin locus as a platform for protein replacement therapy von Sharma, Rajiv, Anguela, Xavier M., Doyon, Yannick, Wechsler, Thomas, DeKelver, Russell C., Sproul, Scott, Paschon, David E., Miller, Jeffrey C., Davidson, Robert J., Shivak, David, Zhou, Shangzhen, Rieders, Julianne, Gregory, Philip D., Holmes, Michael C., Rebar, Edward J., High, Katherine A.

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SON Controls Cell-Cycle Progression by Coordinated Regulation of RNA Splicing von Ahn, Eun-Young, DeKelver, Russell C., Lo, Miao-Chia, Nguyen, Tuyet Ann, Matsuura, Shinobu, Boyapati, Anita, Pandit, Shatakshi, Fu, Xiang-Dong, Zhang, Dong-Er

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases von Amora, Ranier, Miller, Jeffrey C, Mitalipova, Maisam, Katibah, George E, Rebar, Edward J, Urnov, Fyodor D, Jaenisch, Rudolf, Gregory, Philip D, Boydston, Elizabeth A, Beard, Caroline, Hockemeyer, Dirk, Zeitler, Bryan, Meng, Xiangdong, Soldner, Frank, Gao, Qing, Zhang, Lei, DeKelver, Russell C

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Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets von Conway, Anthony, Mendel, Matthew, Kim, Kenneth, McGovern, Kyle, Boyko, Alisa, Zhang, Lei, Miller, Jeffrey C., DeKelver, Russell C., Paschon, David E., Mui, Barbara L., Lin, Paulo J.C., Tam, Ying K., Barbosa, Chris, Redelmeier, Tom, Holmes, Michael C., Lee, Gary

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Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions von Goldberg, Aaron D., Banaszynski, Laura A., Noh, Kyung-Min, Lewis, Peter W., Elsaesser, Simon J., Stadler, Sonja, Dewell, Scott, Law, Martin, Guo, Xingyi, Li, Xuan, Wen, Duancheng, Chapgier, Ariane, DeKelver, Russell C., Miller, Jeffrey C., Lee, Ya-Li, Boydston, Elizabeth A., Holmes, Michael C., Gregory, Philip D., Greally, John M., Rafii, Shahin, Yang, Chingwen, Scambler, Peter J., Garrick, David, Gibbons, Richard J., Higgs, Douglas R., Cristea, Ileana M., Urnov, Fyodor D., Zheng, Deyou, Allis, C. David

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SRSF2 Is Essential for Hematopoiesis, and Its Myelodysplastic Syndrome-Related Mutations Dysregulate Alternative Pre-mRNA Splicing von Komeno, Yukiko, Huang, Yi-Jou, Qiu, Jinsong, Lin, Leo, Xu, YiJun, Zhou, Yu, Chen, Liang, Monterroza, Dora D., Li, Hairi, DeKelver, Russell C., Yan, Ming, Fu, Xiang-Dong, Zhang, Dong-Er

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Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases von Moehle, E.A, Rock, J.M, Lee, Y.L, Jouvenot, Y, DeKelver, R.C, Gregory, P.D, Urnov, F.D, Holmes, M.C

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Precise genome modification in the crop species Zea mays using zinc-finger nucleases von Shukla, Vipula K, Doyon, Yannick, Miller, Jeffrey C, DeKelver, Russell C, Moehle, Erica A, Worden, Sarah E, Mitchell, Jon C, Arnold, Nicole L, Gopalan, Sunita, Meng, Xiangdong, Choi, Vivian M, Rock, Jeremy M, Wu, Ying-Ying, Katibah, George E, Zhifang, Gao

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Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing von Laoharawee, Kanut, DeKelver, Russell C., Podetz-Pedersen, Kelly M., Rohde, Michelle, Sproul, Scott, Nguyen, Hoang-Oanh, Nguyen, Tam, St. Martin, Susan J., Ou, Li, Tom, Susan, Radeke, Robert, Meyer, Kathleen E., Holmes, Michael C., Whitley, Chester B., Wechsler, Thomas, McIvor, R. Scott

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Cooperation between RUNX1-ETO9a and novel transcriptional partner KLF6 in upregulation of Alox5 in acute myeloid leukemia von DeKelver, Russell C, Lewin, Benjamin, Lam, Kentson, Komeno, Yukiko, Yan, Ming, Rundle, Chandler, Lo, Miao-Chia, Zhang, Dong-Er

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Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome von DeKelver, Russell C, Choi, Vivian M, Moehle, Erica A, Paschon, David E, Hockemeyer, Dirk, Meijsing, Sebastiaan H, Sancak, Yasemin, Cui, Xiaoxia, Steine, Eveline J, Miller, Jeffrey C, Tam, Phillip, Bartsevich, Victor V, Meng, Xiangdong, Rupniewski, Igor, Gopalan, Sunita M, Sun, Helena C, Pitz, Kathleen J, Rock, Jeremy M, Zhang, Lei, Davis, Gregory D, Rebar, Edward J, Cheeseman, Iain M, Yamamoto, Keith R, Sabatini, David M, Jaenisch, Rudolf, Gregory, Philip D, Urnov, Fyodor D

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Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology von Orlando, Salvatore J, Santiago, Yolanda, DeKelver, Russell C, Freyvert, Yevgeniy, Boydston, Elizabeth A, Moehle, Erica A, Choi, Vivian M, Gopalan, Sunita M, Lou, Jacqueline F, Li, James, Miller, Jeffrey C, Holmes, Michael C, Gregory, Philip D, Urnov, Fyodor D, Cost, Gregory J

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Chromosomal translocations induced at specified loci in human stem cells von Brunet, Erika, Simsek, Deniz, Tomishima, Mark, DeKelver, Russell, Choi, Vivian M, Gregory, Philip, Urnov, Fyodor, Weinstock, David M, Jasin, Maria

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Targeted transgene integration in plant cells using designed zinc finger nucleases von Cai, Charles Q, Doyon, Yannick, Ainley, W. Michael, Miller, Jeffrey C, DeKelver, Russell C, Moehle, Erica A, Rock, Jeremy M, Lee, Ya-Li, Garrison, Robbi, Schulenberg, Lisa, Blue, Ryan, Worden, Andrew, Baker, Lisa, Faraji, Farhoud, Zhang, Lei, Holmes, Michael C, Rebar, Edward J, Collingwood, Trevor N, Rubin-Wilson, Beth, Gregory, Philip D, Urnov, Fyodor D, Petolino, Joseph F

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Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential von DeKelver, Russell C., Yan, Ming, Ahn, Eun-Young, Shia, Wei-Jong, Speck, Nancy A., Zhang, Dong-Er

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ZFN-Mediated In Vivo Genome Editing Corrects Murine Hurler Syndrome von Ou, Li, DeKelver, Russell C., Rohde, Michelle, Tom, Susan, Radeke, Robert, St. Martin, Susan J., Santiago, Yolanda, Sproul, Scott, Przybilla, Michelle J., Koniar, Brenda L., Podetz-Pedersen, Kelly M., Laoharawee, Kanut, Cooksley, Renee D., Meyer, Kathleen E., Holmes, Michael C., McIvor, R. Scott, Wechsler, Thomas, Whitley, Chester B.

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The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling von Stoner, Samuel A., Liu, Katherine Tin Heng, Andrews, Elizabeth T., Liu, Mengdan, Arimoto, Kei-Ichiro, Yan, Ming, Davis, Amanda G., Weng, Stephanie, Dow, Michelle, Xian, Su, DeKelver, Russell C., Carter, Hannah, Zhang, Dong-Er

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Transcriptional activation of Brassica napus β-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor von Gupta, Manju, DeKelver, Russell C., Palta, Asha, Clifford, Carla, Gopalan, Sunita, Miller, Jeffrey C., Novak, Stephen, Desloover, Daniel, Gachotte, Daniel, Connell, James, Flook, Josh, Patterson, Thomas, Robbins, Kelly, Rebar, Edward J., Gregory, Philip D., Urnov, Fyodor D., Petolino, Joseph F.

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SON Protein Regulates GATA-2 through Transcriptional Control of the MicroRNA 23a∼27a∼24-2 Cluster von Ahn, Erin Eun-Young, Higashi, Tsunehito, Yan, Ming, Matsuura, Shinobu, Hickey, Christopher J., Lo, Miao-Chia, Shia, Wei-Jong, DeKelver, Russell C., Zhang, Dong-Er

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RUNX1-ETO-Dependent Transcriptional Repression of RASSF2 Contributes to t(8;21) Leukemia through Evasion of MST1-Driven Apoptosis Signaling von Stoner, Samuel A., Andrews, Elizabeth T., Dekelver, Russell, Weng, Stephanie, Lo, Miao-Chia, Guan, Kun-Liang, Zhang, Dong-Er

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