The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice von Jia, Haiqun, Wang, Ying, Morris, Charles D, Jacques, Vincent, Gottesfeld, Joel M, Rusche, James R, Thomas, Elizabeth A

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HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner von Malvaez, Melissa, McQuown, Susan C., Rogge, George A., Astarabadi, Mariam, Jacques, Vincent, Carreiro, Samantha, Rusche, James R., Wood, Marcelo A.

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Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model von Rai, Myriam, Soragni, Elisabetta, Chou, C James, Barnes, Glenn, Jones, Steve, Rusche, James R, Gottesfeld, Joel M, Pandolfo, Massimo

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HDAC3 is a critical negative regulator of long-term memory formation von McQuown, Susan C, Barrett, Ruth M, Matheos, Dina P, Post, Rebecca J, Rogge, George A, Alenghat, Theresa, Mullican, Shannon E, Jones, Steven, Rusche, James R, Lazar, Mitchell A, Wood, Marcelo A

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Epigenetic therapy for Friedreich ataxia von Soragni, Elisabetta, Miao, Wenyan, Iudicello, Marco, Jacoby, David, De Mercanti, Stefania, Clerico, Marinella, Longo, Filomena, Piga, Antonio, Ku, Sherman, Campau, Erica, Du, Jintang, Penalver, Pablo, Rai, Myriam, Madara, Joseph C., Nazor, Kristopher, O'Connor, Melinda, Maximov, Anton, Loring, Jeanne F., Pandolfo, Massimo, Durelli, Luca, Gottesfeld, Joel M., Rusche, James R.

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Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease von Jia, Haiqun, Pallos, Judit, Jacques, Vincent, Lau, Alice, Tang, Bin, Cooper, Andrew, Syed, Adeela, Purcell, Judith, Chen, Yi, Sharma, Shefali, Sangrey, Gavin R, Darnell, Shayna B, Plasterer, Heather, Sadri-Vakili, Ghazaleh, Gottesfeld, Joel M, Thompson, Leslie M, Rusche, James R, Marsh, J. Lawrence, Thomas, Elizabeth A

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Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies von Matthews, Geoffrey M., Mehdipour, Parinaz, Cluse, Leonie A., Falkenberg, Katrina J., Wang, Eric, Roth, Mareike, Santoro, Fabio, Vidacs, Eva, Stanley, Kym, House, Colin M., Rusche, James R., Vakoc, Christopher R., Zuber, Johannes, Minucci, Saverio, Johnstone, Ricky W.

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Prolonged treatment with pimelic o -aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model von Sandi, Chiranjeevi, Pinto, Ricardo Mouro, Al-Mahdawi, Sahar, Ezzatizadeh, Vahid, Barnes, Glenn, Jones, Steve, Rusche, James R, Gottesfeld, Joel M, Pook, Mark A

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The DcpS inhibitor RG3039 improves motor function in SMA mice von Van Meerbeke, James P, Gibbs, Rebecca M, Plasterer, Heather L, Miao, Wenyan, Feng, Zhihua, Lin, Ming-Yi, Rucki, Agnieszka A, Wee, Claribel D, Xia, Bing, Sharma, Shefali, Jacques, Vincent, Li, Darrick K, Pellizzoni, Livio, Rusche, James R, Ko, Chien-Ping, Sumner, Charlotte J

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Development of frataxin gene expression measures for the evaluation of experimental treatments in Friedreich's ataxia von Plasterer, Heather L, Deutsch, Eric C, Belmonte, Matthew, Egan, Elizabeth, Lynch, David R, Rusche, James R

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Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia von Soragni, Elisabetta, Chou, C James, Rusche, James R, Gottesfeld, Joel M

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Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia von Gottesfeld, Joel M., Rusche, James R., Pandolfo, Massimo

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Histone Deacetylase Inhibition via RGFP966 Releases the Brakes on Sensory Cortical Plasticity and the Specificity of Memory Formation von Bieszczad, Kasia M, Bechay, Kiro, Rusche, James R, Jacques, Vincent, Kudugunti, Shashi, Miao, Wenyan, Weinberger, Norman M, McGaugh, James L, Wood, Marcelo A

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Effects of uridine in models of epileptogenesis and seizures von Zhao, Qian, Marolewski, Ariane, Rusche, James R., Holmes, Gregory L.

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Improved Histone Deacetylase Inhibitors as Therapeutics for the Neurodegenerative Disease Friedreich's Ataxia: A New Synthetic Route von Xu, Chunping, Soragni, Elisabetta, Jacques, Vincent, Rusche, James R, Gottesfeld, Joel M

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Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression von Bhaskara, Srividya, Jacques, Vincent, Rusche, James R, Olson, Eric N, Cairns, Bradley R, Chandrasekharan, Mahesh B

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Unique Structures Generated by Ugi 3CC Reactions Using Bifunctional Starting Materials Containing Aldehyde and Carboxylic Acid von Zhang, Jundong, Jacobson, Alan, Rusche, James R, Herlihy, Walter

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A gene expression phenotype in lymphocytes from friedreich ataxia patients von Coppola, Giovanni, Burnett, Ryan, Perlman, Susan, Versano, Revital, Gao, Fuying, Plasterer, Heather, Rai, Myriam, Saccá, Francesco, Filla, Alessandro, Lynch, David R., Rusche, James R., Gottesfeld, Joel M., Pandolfo, Massimo, Geschwind, Daniel H.

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Increased long-term potentiation at medial-perforant path-dentate granule cell synapses induced by selective inhibition of histone deacetylase 3 requires Fragile X mental retardati... von Franklin, Aimee V., Rusche, James R., McMahon, Lori L.

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Rationale for the Development of 2-Aminobenzamide Histone Deacetylase Inhibitors as Therapeutics for Friedreich Ataxia von Soragni, Elisabetta, Xu, Chunping, Plasterer, Heather L., Jacques, Vincent, Rusche, James R., Gottesfeld, Joel M.

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