Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 inhibitors leading to the identification of a clinical candidate von Dvorak, Curt A., Rudolph, Dale A., Nepomuceno, Diane, Dvorak, Lisa, Lord, Brian, Fraser, Ian, Bonaventure, Pascal, Lovenberg, Timothy, Carruthers, Nicholas I.

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Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists von Rudolph, Dale A., Alcazar, Jesus, Ameriks, Michael K., Anton, Ana Belen, Ao, Hong, Bonaventure, Pascal, Carruthers, Nicholas I., Chrovian, Christa C., De Angelis, Meri, Lord, Brian, Rech, Jason C., Wang, Qi, Bhattacharya, Anindya, Andres, Jose Ignacio, Letavic, Michael A.

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Substituted 5,6-(Dihydropyrido[3,4‑d]pyrimidin-7(8H)‑yl)-methanones as P2X7 Antagonists von Ziff, Jeannie, Rudolph, Dale A, Stenne, Brice, Koudriakova, Tatiana, Lord, Brian, Bonaventure, Pascal, Lovenberg, Timothy W, Carruthers, Nicholas I, Bhattacharya, Anindya, Letavic, Michael A, Shireman, Brock T

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Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids von Dvorak, Curt A, Rudolph, Dale A, Ma, Sandy, Carruthers, Nicholas I

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor von Swanson, Devin M., Wong, Victoria D., Jablonowski, Jill A., Shah, Chandra, Rudolph, Dale A., Dvorak, Curt A., Seierstad, Mark, Dvorak, Lisa K., Morton, Kirsten, Nepomuceno, Diane, Atack, John R., Bonaventure, Pascal, Lovenberg, Timothy W., Carruthers, Nicholas I.

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Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT7 antagonists von Rudolph, Dale A., Dvorak, Curt A., Dvorak, Lisa, Nepomuceno, Diane, Bonaventure, Pascal, Lovenberg, Timothy W., Carruthers, Nicholas I.

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Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX 2R) antagonists von McAtee, Laura C, Sutton, Steven W, Rudolph, Dale A, Li, Xiaobing, Aluisio, Leah E, Phuong, Victor K, Dvorak, Curt A, Lovenberg, Timothy W, Carruthers, Nicholas I, Jones, Todd K

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2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists von SHIREMAN, Brock T, DVORAK, Curt A, RUDOLPH, Dale A, BONAVENTURE, Pascal, NEPOMUCENO, Diane, DVORAK, Lisa, MILLER, Kirsten L, LOVENBERG, Timothy W, CARRUTHERS, Nicholas I

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Novel non-peptidic neuropeptide Y Y2 receptor antagonists von JABLONOWSKI, Jill A, WENYING CHAI, CARRUTHERS, Nicholas I, XIAOBING LI, RUDOLPH, Dale A, MURRAY, William V, YOUNGMAN, Mark A, DAX, Scott L, NEPOMUCENO, Diane, BONAVENTURE, Pascal, LOVENBERG, Timothy W

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Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT 7/2 inhibitors leading to the identification of a clinical candidate von Dvorak, Curt A, Rudolph, Dale A, Nepomuceno, Diane, Dvorak, Lisa, Lord, Brian, Fraser, Ian, Bonaventure, Pascal, Lovenberg, Timothy, Carruthers, Nicholas I

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Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT sub(7) antagonists von Rudolph, Dale A, Dvorak, Curt A, Dvorak, Lisa, Nepomuceno, Diane, Bonaventure, Pascal, Lovenberg, Timothy W, Carruthers, Nicholas I

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y sub(2) receptor von Swanson, Devin M, Wong, Victoria D, Jablonowski, Jill A, Shah, Chandra, Rudolph, Dale A, Dvorak, Curt A, Seierstad, Mark, Dvorak, Lisa K, Morton, Kirsten, Nepomuceno, Diane, Atack, John R, Bonaventure, Pascal, Lovenberg, Timothy W, Carruthers, Nicholas I

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Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108] von Shireman, Brock T., Dvorak, Curt A., Rudolph, Dale A., Bonaventure, Pascal, Nepomuceno, Diane, Dvorak, Lisa, Miller, Kirsten L., Lovenberg, Timothy W., Carruthers, Nicholas I.

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Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108] von Shireman, Brock T., Dvorak, Curt A., Rudolph, Dale A., Bonaventure, Pascal, Nepomuceno, Diane, Dvorak, Lisa, Miller, Kirsten L., Lovenberg, Timothy W., Carruthers, Nicholas I.

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2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists von Shireman, Brock T., Dvorak, Curt A., Rudolph, Dale A., Bonaventure, Pascal, Nepomuceno, Diane, Dvorak, Lisa, Miller, Kirsten L., Lovenberg, Timothy W., Carruthers, Nicholas I.

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Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists von Rudolph, Dale A, Dvorak, Curt A, Dvorak, Lisa, Nepomuceno, Diane, Bonaventure, Pascal, Lovenberg, Timothy W, Carruthers, Nicholas I

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PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING A P2X7 MODULATOR von LETAVIC, Michael A, RUDOLPH, Dale A

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P2X7 MODULATING N-ACYL-TRIAZOLOPYRAZINES von RECH, JASON C, ANDRES GIL, JOSE IGNACIO, LETAVIC, MICHAEL A, RUDOLPH, DALE A, SOYODE-JOHNSON, AKINOLA, CHROVIAN, CHRISTA C

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P2X7 modulators von Letavic, Michael A, Rudolph, Dale A

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SUBSTITUTED 1H-IMIDAZO[4,5-b]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS von Wall, Jessica L, Rech, Jason C, Stenne, Brice M, Letavic, Michael A, Rudolph, Dale A, Soyode-Johnson, Akinola, Chrovian, Christa C

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