Amylin: Pharmacology, Physiology, and Clinical Potential von Hay, Debbie L, Chen, Steve, Lutz, Thomas A, Parkes, David G, Roth, Jonathan D

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Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment von Clapper, Jason R, Hendricks, Michelle D, Gu, Guibao, Wittmer, Carrie, Dolman, Carrie S, Herich, John, Athanacio, Jennifer, Villescaz, Christiane, Ghosh, Soumitra S, Heilig, Joseph S, Lowe, Carolyn, Roth, Jonathan D

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FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver von Papazyan, Romeo, Liu, Xueqing, Liu, Jingwen, Dong, Bin, Plummer, Emily M., Lewis, Ronald D., Roth, Jonathan D., Young, Mark A.

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Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice von Trevaskis, James L, Griffin, Peter S, Wittmer, Carrie, Neuschwander-Tetri, Brent A, Brunt, Elizabeth M, Dolman, Carrie S, Erickson, Mary R, Napora, James, Parkes, David G, Roth, Jonathan D

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Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies von Roth, Jonathan D, Roland, Barbara L, Cole, Rebecca L, Trevaskis, James L, Weyer, Christian, Koda, Joy E, Anderson, Christen M, Parkes, David G, Baron, Alain D

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Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms von Trevaskis, James L, Coffey, Todd, Cole, Rebecca, Lei, Chunli, Wittmer, Carrie, Walsh, Brandon, Weyer, Christian, Koda, Joy, Baron, Alain D, Parkes, David G, Roth, Jonathan D

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Mechanisms of Amylin/Leptin Synergy in Rodent Models von Turek, Victoria F, Trevaskis, James L, Levin, Barry E, Dunn-Meynell, Ambrose A, Irani, Boman, Gu, Guibao, Wittmer, Carrie, Griffin, Peter S, Vu, Calvin, Parkes, David G, Roth, Jonathan D

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Effects of amylin and bupropion/naltrexone on food intake and body weight are interactive in rodent models von Clapper, Jason R., Athanacio, Jennifer, Wittmer, Carrie, Griffin, Pete S., D'Souza, Lawrence, Parkes, David G., Roth, Jonathan D.

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Amylin and the regulation of appetite and adiposity: recent advances in receptor signaling, neurobiology and pharmacology von Roth, Jonathan D.

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Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH von Roth, Jonathan D., Veidal, Sanne S., Fensholdt, Louise K. D., Rigbolt, Kristoffer T. G., Papazyan, Romeo, Nielsen, Jens Christian, Feigh, Michael, Vrang, Niels, Young, Mark, Jelsing, Jacob, Adorini, Luciano, Hansen, Henrik H.

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GLP‐1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities von Roth, Jonathan D, Erickson, Mary R, Chen, Steve, Parkes, David G

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Antiobesity Effects of the β-Cell Hormone Amylin in Diet-Induced Obese Rats: Effects on Food Intake, Body Weight, Composition, Energy Expenditure, and Gene Expression von Roth, Jonathan D, Hughes, Heather, Kendall, Eric, Baron, Alain D, Anderson, Christen M

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Insights into amylin–leptin synergy von Trevaskis, James L, Parkes, David G, Roth, Jonathan D

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Interaction of Leptin and Amylin in the Long-term Maintenance of Weight Loss in Diet-induced Obese Rats von Trevaskis, James L, Lei, Chunli, Koda, Joy E, Weyer, Christian, Parkes, David G, Roth, Jonathan D

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Simultaneous quantification of the glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) receptor agonists in rodent plasma by on-line solid phase extraction and LC–MS/MS von Wang, Yan, Roth, Jonathan D., Taylor, Steven W.

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Noradrenergic neurons of the area postrema mediate amylin's hypophagic action von Potes, Catarina S, Turek, Victoria F, Cole, Rebecca L, Vu, Calvin, Roland, Barbara L, Roth, Jonathan D, Riediger, Thomas, Lutz, Thomas A

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Aberrant basement membrane production by HSCs in MASLD is attenuated by the bile acid analog INT-767 von Ramachandran, Prakash, Brice, Madara, Sutherland, Elena F, Hoy, Anna M, Papachristoforou, Eleni, Jia, Li, Turner, Frances, Kendall, Timothy J, Marwick, John A, Carragher, Neil O, Oro, Denise, Feigh, Michael, Leeming, Diana J, Nielsen, Mette J, Karsdal, Morten A, Hartmann, Nadine, Erickson, Mary, Adorini, Luciano, Roth, Jonathan D, Fallowfield, Jonathan A

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Enhanced Amylin-Mediated Body Weight Loss in Estradiol-Deficient Diet-Induced Obese Rats von Trevaskis, James L, Turek, Victoria F, Wittmer, Carrie, Griffin, Peter S, Wilson, Julie K, Reynolds, James M, Zhao, Yu, Mack, Christine M, Parkes, David G, Roth, Jonathan D

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Combination Therapy with Amylin and Peptide YY[3–36] in Obese Rodents: Anorexigenic Synergy and Weight Loss Additivity von Roth, Jonathan D, Coffey, Todd, Jodka, Carolyn M, Maier, Holly, Athanacio, Jennifer R, Mack, Christine M, Weyer, Christian, Parkes, David G

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“Weighing in” on synergy: Preclinical research on neurohormonal anti-obesity combinations von Roth, Jonathan D, Trevaskis, James L, Turek, Victoria F, Parkes, David G

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