Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature von Awong, Génève, Herer, Elaine, La Motte-Mohs, Ross N, Zúñiga-Pflücker, Juan Carlos

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P997: FEDRATINIB IS EFFECTIVE IN RUXOLITINIB‐RESISTANT CELLS: CLINICAL AND PRECLINICAL CORRELATIONS von Jeyaraju, Danny, Hayati, Sheida, Polonskaia, Ann, Browne, Andrew, Risueño, Alberto, Hagner, Patrick, Gupta, Vikas, Talpaz, Moshe, Hernandez, Christopher, Chia, Vincent, Brown, Patrick, De Menezes, Daniel Lopes, La Motte‐Mohs, Ross, Nvs Suragani, Rajasekhar, Gandhi, Anita

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Nivolumab, Pomalidomide, and Elotuzumab Combination Regimens for Treatment of Relapsed and Refractory Multiple Myeloma: Results from the Phase 3 CheckMate 602 Study von Oriol, Albert, Hájek, Roman, Spicka, Ivan, Sandhu, Irwindeep, Cohen, Yael C., Gatt, Moshe E., Mariz, José, Cavo, Michele, Berdeja, Jesús, Jin, Kexin, Bar, Merav, Das, Prianka, Motte-Mohs, Ross La, Wang, Yu, Perumal, Deepak, Costa, Luciano J.

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Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture von Awong, Génève, Singh, Jastaranpreet, Mohtashami, Mahmood, Malm, Maria, La Motte-Mohs, Ross N., Benveniste, Patricia M., Serra, Pablo, Herer, Elaine, van den Brink, Marcel R., Zúñiga-Pflücker, Juan Carlos

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Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro von La Motte-Mohs, Ross N., Herer, Elaine, Zúñiga-Pflücker, Juan Carlos

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Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells von Awong, Génève, Herer, Elaine, Surh, Charles D., Dick, John E., La Motte-Mohs, Ross N., Zúñiga-Pflücker, Juan Carlos

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In Vitro Models of Human T Cell Development: Dishing Out Progenitor T Cells von La Motte-Mohs, Ross N, Awong, Geneve, Carlos Zuniga-Pflucker, Juan

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The Role of Nuclear Factor-κB Essential Modulator (NEMO) in B Cell Development and Survival von Kim, Shinyop, Ross N. A. La Motte-Mohs, Rudolph, Dorothea, Zúñiga-Pflücker, Juan Carlos, Mak, Tak W.

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TLR Ligand-Induced Type I IFNs Affect Thymopoiesis von Baron, Marie-Laurence, Gauchat, Dominique, La Motte-Mohs, Ross, Kettaf, Nadia, Abdallah, Ali, Michiels, Thomas, Zuniga-Pflucker, Juan-Carlos, Sekaly, Rafick-Pierre

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Generation of pro-T cells in vitro : potential for immune reconstitution von Awong, Génève, La Motte-Mohs, Ross N, Zúñiga-Pflücker, Juan Carlos

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In Vitro Human T Cell Development Directed by Notch–Ligand Interactions von Awong, Génève, Motte-Mohs, Ross N. La, Zúñiga-Pflücker, Juan Carlos

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Suppression of Myeloid Cell-Derived Proinflammatory Cytokines with Celmod Agents: Implications for CRS with T-Cell Engagers (TCEs) von Jeyaraju, Danny V, Alapa, Maryam, O'Donohue, Aimee, La Motte-Mohs, Ross, Boss, Isaac W., Hagner, Patrick, Pourdehnad, Michael, Burgess, Michael R., Pierceall, William E., Thakurta, Anjan

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P-025 Synergistic antitumor activity of the BCMA 2+1 T-cell engager (TCE) alnuctamab (ALNUC; BMS-986349; CC-93269) and CELMoD agents in multiple myeloma (MM) preclinical models von Paiva, Bruno, Gaffney, Bonny, Burnett, Kelven, Castiglioni, Paola, La Motte-Mohs, Ross, Angelo, Michael, Pierce, Daniel, Boss, Isaac

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Abstract CT085: Pharmacodynamic correlates in a phase I study of INCMGA00012, a PD-1 antagonistic monoclonal antibody von Condamine, Thomas, Owens, Sherry, Feldman, Patricia, Motte-Mohs, Ross La, Muth, John, Sumrow, Bradley, Moore, Paul, Newton, Robert

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Fedratinib Induces Cytokine Changes Correlating with Clinical Response in Ruxolitinib Exposed Myelofibrosis Patients: Biomarker Analysis from the Freedom Trial von Jeyaraju, Danny V, Hayati, Sheida, Polonskaia, Ann, Alapa, Maryam, Ugidos, Manuel, Browne, Andrew, Risueño, Alberto, Hagner, Patrick, Gupta, Vikas, Talpaz, Moshe, Hernandez, Christopher, Chia, Vincent, Martin-Regueira, Patricia, Lopes de Menezes, Daniel, La Motte-Mohs, Ross, Suragani, Rajasekhar NVS, Gandhi, Anita K.

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A phase 1, open label, dose escalation study of MGD009, a humanized B7-H3 x CD3 DART protein, in combination with MGA012, an anti-PD-1 antibody, in patients with relapsed or refrac... von Shankar, Sadhna, Spira, Alexander I., Strauss, James, Liu, Liqin, La Motte-Mohs, Ross, Wu, Tony, Johnson, Syd, Bonvini, Ezio, Moore, Paul A., Wigginton, Jon M., Vasselli, Jim

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The role of nuclear factor-kappaB essential modulator (NEMO) in B cell development and survival von Kim, Shinyop, La Motte-Mohs, Ross N A, Rudolph, Dorothea, Zuniga-Pflucker, Juan Carlos, Mak, Tak W

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Adaptive Immune Gene Signatures Correlate with Response to Flotetuzumab, a CD123 × CD3 Bispecific Dart® Molecule, in Patients with Relapsed/Refractory Acute Myeloid Leukemia von Rutella, Sergio, Church, Sarah E., Vadakekolathu, Jayakumar, Viboch, Elena, Sullivan, Amy H, Hood, Tressa, Warren, Sarah E., Cesano, Alessandra, La Motte-Mohs, Ross, Muth, John, Lelièvre, Helene, Lowenberg, Bob, DiPersio, John F., Davidson-Moncada, Jan K

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A Next-Generation Fc-Bearing CD3-Engaging Bispecific DART® Platform with Extended Pharmacokinetic and Expanded Pharmacologic Window: Characterization As CD123 x CD3 and CD19 x CD3... von Bonvini, Ezio, La Motte-Mohs, Ross, Huang, Ling, Lam, Chia-Ying Kao, Kaufman, Thomas, Liu, Liqin, Alderson, Ralph F., Stahl, Kurt, Brown, Jennifer G., Li, Hua, Sharma, Sharad, Tamura, James, Johnson, Syd, Moore, Paul

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Adaptive Immune Gene Signatures Correlate with Response to Flotetuzumab, a CD123 X CD3 Bispecific Dart (R) Molecule, in Patients with Relapsed/Refractory Acute Myeloid Leukemia von Rutella, Sergio, Church, Sarah E., Vadakekolathu, Jayakumar, Viboch, Elena, Sullivan, Amy H., Hood, Tressa, Warren, Sarah E., Cesano, Alessandra, La Motte-Mohs, Ross, Muth, John, Lelievre, Helene, Lowenberg, Bob, Dipersio, John F., Davidson-Moncada, Jan K.

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