Synthesis of Diastereomerically Pure Nucleotide Phosphoramidates von Ross, Bruce S, Ganapati Reddy, P, Zhang, Hai-Ren, Rachakonda, Suguna, Sofia, Michael J

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Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase von Sofia, Michael J, Chang, Wonsuk, Furman, Phillip A, Mosley, Ralph T, Ross, Bruce S

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PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication von LAM, Angela M, MURAKAMI, Eisuke, MORREY, John D, SMEE, Donald F, FRICK, David N, HECK, Julie A, PEIYUAN WANG, NAGARATHNAM, Dhanapalan, ROSS, Bruce S, SOFIA, Michael J, OTTO, Michael J, FURMAN, Phillip A, ESPIRITU, Christine, MICOLOCHICK STEUER, Holly M, NIU, Congrong, KEILMAN, Meg, HAIYING BAO, ZENNOU, Veronique, BOURNE, Nigel, JULANDER, Justin G

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An Efficient and Diastereoselective Synthesis of PSI-6130: A Clinically Efficacious Inhibitor of HCV NS5B Polymerase von Wang, Peiyuan, Chun, Byoung-Kwon, Rachakonda, Suguna, Du, Jinfa, Khan, Noshena, Shi, Junxing, Stec, Wojciech, Cleary, Darryl, Ross, Bruce S, Sofia, Michael J

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A Chemical Approach to Introduce 2,6-Diaminopurine and 2‑Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups von Madaoui, Mimouna, Datta, Dhrubajyoti, Wassarman, Kelly, Zlatev, Ivan, Egli, Martin, Ross, Bruce S., Manoharan, Muthiah

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Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides:  Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal S... von Egli, Martin, Minasov, George, Tereshko, Valentina, Pallan, Pradeep S, Teplova, Marianna, Inamati, Gopal B, Lesnik, Elena A, Owens, Steve R, Ross, Bruce S, Prakash, Thazha P, Manoharan, Muthiah

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Comparing In Vitro and In Vivo Activity of 2′-O-[2-(Methylamino)-2-oxoethyl]- and 2′-O-Methoxyethyl-Modified Antisense Oligonucleotides von Prakash, Thazha P, Kawasaki, Andrew M, Wancewicz, Edward V, Shen, Lijiang, Monia, Brett P, Ross, Bruce S, Bhat, Balkrishen, Manoharan, Muthiah

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Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus von Sofia, Michael J, Bao, Donghui, Chang, Wonsuk, Du, Jinfa, Nagarathnam, Dhanapalan, Rachakonda, Suguna, Reddy, P. Ganapati, Ross, Bruce S, Wang, Peiyuan, Zhang, Hai-Ren, Bansal, Shalini, Espiritu, Christine, Keilman, Meg, Lam, Angela M, Steuer, Holly M. Micolochick, Niu, Congrong, Otto, Michael J, Furman, Phillip A

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Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV Infection von Chang, Wonsuk, Bao, Donghui, Chun, Byoung-Kwon, Naduthambi, Devan, Nagarathnam, Dhanapalan, Rachakonda, Suguna, Reddy, P. Ganapati, Ross, Bruce S, Zhang, Hai-Ren, Bansal, Shalini, Espiritu, Christine L, Keilman, Meg, Lam, Angela M, Niu, Congrong, Steuer, Holly Micolochick, Furman, Phillip A, Otto, Michael J, Sofia, Michael J

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Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides von Chang, Wonsuk, Du, Jinfa, Rachakonda, Suguna, Ross, Bruce S., Convers-Reignier, Serge, Yau, Wei T., Pons, Jean-Francois, Murakami, Eisuke, Bao, Haiying, Steuer, Holly Micolochick, Furman, Phillip A., Otto, Michael J., Sofia, Michael J.

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Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase von Sofia, Michael J, Chang, Wonsuk, Furman, Phillip A, Mosley, Ralph T, Ross, Bruce S

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Stereoselective Synthesis of PSI-352938: A β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyl-3′,5′-cyclic Phosphate Nucleotide Prodrug for the Treatment of HCV von Reddy, P. Ganapati, Chun, Byoung-Kwon, Zhang, Hai-Ren, Rachakonda, Suguna, Ross, Bruce S, Sofia, Michael J

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Confidentiality, privacy and disclosure in and out of the courtroom: the American experience von Ross, Bruce S.

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2′-Deoxy-2′-α-fluoro-2′-β- C-methyl 3′,5′-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: Discovery of PSI-352938 von Reddy, P. Ganapati, Bao, Donghui, Chang, Wonsuk, Chun, Byoung-Kwon, Du, Jinfa, Nagarathnam, Dhanapalan, Rachakonda, Suguna, Ross, Bruce S., Zhang, Hai-Ren, Bansal, Shalini, Espiritu, Christine L., Keilman, Meg, Lam, Angela M., Niu, Congrong, Steuer, Holly Micolochick, Furman, Phillip A., Otto, Michael J., Sofia, Michael J.

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Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661 von Furman, Phillip A., Murakami, Eisuke, Niu, Congrong, Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Bao, Haiying, Tolstykh, Tatiana, Micolochick Steuer, Holly, Keilman, Meg, Zennou, Veronique, Bourne, Nigel, Veselenak, Ronald L., Chang, Wonsuk, Ross, Bruce S., Du, Jinfa, Otto, Michael J., Sofia, Michael J.

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N-(2-Cyanoethoxycarbonyloxy)succinimide:  A New Reagent for Protection of Amino Groups in Oligonucleotides von Manoharan, Muthiah, Prakash, Thazha P, Barber-Peoc'h, Isabelle, Bhat, Balkrishen, Vasquez, Guillermo, Ross, Bruce S, Cook, P. Dan

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Rapid differentiation of nucleotide phosphoramidate diastereomers by electrospray ionization tandem mass spectrometry von Bao, Donghui, Reddy, P. Ganapati, Ross, Bruce S., Sofia, Michael J.

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A liquid chromatography-tandem mass spectrometry method for the quantitative determination of diastereomers of a phosphoramidate nucleotide prodrug (PSI-7851) in human plasma von Bao, Donghui, Ross, Bruce S., Sofia, Michael J.

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Correction to Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance,... von Egli, Martin, Minasov, George, Tereshko, Valentina, Pallan, Pradeep S, Teplova, Marianna, Inamati, Gopal B, Lesnik, Elena A, Owens, Steve R, Ross, Bruce S, Prakash, Thazha P, Manoharan, Muthiah

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β-d-2′-α-F-2′-β-C-Methyl-6-O-substituted 3′,5′-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: A structure–activity relationship study... von Du, Jinfa, Bao, Donghui, Chun, Byoung-Kwon, Jiang, Ying, Ganapati Reddy, P., Zhang, Hai-Ren, Ross, Bruce S., Bansal, Shalini, Bao, Haiying, Espiritu, Christine, Lam, Angela M., Murakami, Eisuke, Niu, Congrong, Micolochick Steuer, Holly M., Furman, Phillip A., Otto, Michael J., Sofia, Michael J.

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