Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited von Bryan, Marian C., Dunn, Peter J., Entwistle, David, Gallou, Fabrice, Koenig, Stefan G., Hayler, John D., Hickey, Matthew R., Hughes, Shaun, Kopach, Michael E., Moine, Gerard, Richardson, Paul, Roschangar, Frank, Steven, Alan, Weiberth, Franz J.

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The Eight Criteria Defining a Good Chemical Manufacturing Process von Dach, Rolf, Song, Jinhua J, Roschangar, Frank, Samstag, Wendelin, Senanayake, Chris H

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General and Stereoselective Method for the Synthesis of Sterically Congested and Structurally Diverse P‑Stereogenic Secondary Phosphine Oxides von Han, Zhengxu S, Wu, Hao, Xu, Yibo, Zhang, Yongda, Qu, Bo, Li, Zhibin, Caldwell, Donald R, Fandrick, Keith R, Zhang, Li, Roschangar, Frank, Song, Jinhua J, Senanayake, Chris H

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Efficient Asymmetric Synthesis of Structurally Diverse P-Stereogenic Phosphinamides for Catalyst Design von Han, Zhengxu S., Zhang, Li, Xu, Yibo, Sieber, Joshua D., Marsini, Maurice A., Li, Zhibin, Reeves, Jonathan T., Fandrick, Keith R., Patel, Nitinchandra D., Desrosiers, Jean-Nicolas, Qu, Bo, Chen, Anji, Rudzinski, DiAndra M., Samankumara, Lalith P., Ma, Shengli, Grinberg, Nelu, Roschangar, Frank, Yee, Nathan K., Wang, Guijun, Song, Jinhua J., Senanayake, Chris H.

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Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement von Marsini, Maurice A, Buono, Frederic G, Lorenz, Jon C, Yang, Bing-Shiou, Reeves, Jonathan T, Sidhu, Kanwar, Sarvestani, Max, Tan, Zhulin, Zhang, Yongda, Li, Ning, Lee, Heewon, Brazzillo, Jason, Nummy, Laurence J, Chung, J C, Luvaga, Irungu K, Narayanan, Bikshandarkoil A, Wei, Xudong, Song, Jinhua J, Roschangar, Frank, Yee, Nathan K, Senanayake, Chris H

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API Syntheses in Aqueous Media: Assessing the Environmental Footprint en route from Academic Discovery to Industrial Applications as “Green Opportunity” for Process Chemistry von Fleck, Nico, Roschangar, Frank, Haydl, Alexander M.

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A deeper shade of green: inspiring sustainable drug manufacturing von Roschangar, Frank, Colberg, Juan, Dunn, Peter J, Gallou, Fabrice, Hayler, John D, Koenig, Stefan G, Kopach, Michael E, Leahy, David K, Mergelsberg, Ingrid, Tucker, John L, Sheldon, Roger A, Senanayake, Chris H

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Development of a Large Scale Asymmetric Synthesis of the Glucocorticoid Agonist BI 653048 BS H3PO4 von Reeves, Jonathan T, Fandrick, Daniel R, Tan, Zhulin, Song, Jinhua J, Rodriguez, Sonia, Qu, Bo, Kim, Soojin, Niemeier, Oliver, Li, Zhibin, Byrne, Denis, Campbell, Scot, Chitroda, Ashish, DeCroos, Phil, Fachinger, Thomas, Fuchs, Victor, Gonnella, Nina C, Grinberg, Nelu, Haddad, Nizar, Jäger, Burkhard, Lee, Heewon, Lorenz, Jon C, Ma, Shengli, Narayanan, Bikshandarkoil A, Nummy, Larry J, Premasiri, Ajith, Roschangar, Frank, Sarvestani, Max, Shen, Sherry, Spinelli, Earl, Sun, Xiufeng, Varsolona, Richard J, Yee, Nathan, Brenner, Michael, Senanayake, Chris H

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A Novel One-Pot, Two-Step Synthesis of Polycyclic Indoles via Tandem Intramolecular Hydroamidation/Palladium-Catalyzed Annulation von Liu, Jianxiu, Zhang, Yongda, Li, Guisheng, Roschangar, Frank, Farina, Vittorio, Senanayake, Chris H., Lu, Bruce Z.

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Editorial overview: Metrics for green chemistry (2022) von Gallou, Fabrice, Roschangar, Frank

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Practical total synthesis of (+)-Camptothecin: The full story von Ciufolini, Marco A., Roschangar, Frank

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New class of P-stereogenic chiral Brønsted acid catalysts derived from chiral phosphinamides von Han, Zhengxu S., Wu, Hao, Qu, Bo, Wang, Yuwen, Wu, Ling, Zhang, Li, Xu, Yibo, Wu, Linglin, Zhang, Yongda, Lee, Heewon, Roschangar, Frank, Song, Jeff J., Senanayake, Chris H.

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P‐Stereogenic Chiral Phosphine−Palladium Complex Catalyzed Enantioselective Synthesis of Phosphoryl‐Substituted Atropisomeric Vinylarenes von Wu, Hao, Han, Zhengxu S., Qu, Bo, Wang, Dan, Zhang, Yongda, Xu, Yibo, Grinberg, Nelu, Lee, Heewon, Song, Jinhua J., Roschangar, Frank, Wang, Guijun, Senanayake, Chris H.

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Development of a Large-Scale Asymmetric Process for tert-Butanesulfinamide von DeCroos, Philomen, Han, Zhengxu S, Sidhu, Kanwar, Lorenz, Jon, Nummy, Larry, Byrne, Denis, Qu, Bo, Xu, Yibo, Wu, Ling, Lee, Heewon, Roschangar, Frank, Song, Jinhua J, Senanayake, Chris H

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A Michael Equilibration Model To Control Site Selectivity in the Condensation toward Aminopyrazoles von Fandrick, Daniel R, Sanyal, Sanjit, Kaloko, Joseph, Mulder, Jason A, Wang, Yuwen, Wu, Ling, Lee, Heewon, Roschangar, Frank, Hoffmann, Matthias, Senanayake, Chris H

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Chemical Biology of Epothilones von Nicolaou, K. C., Roschangar, Frank, Vourloumis, Dionisios

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The First Regioselective Palladium-Catalyzed Indolization of 2-Bromo- or 2-Chloroanilines with Internal Alkynes:  A New Approach to 2,3-Disubstituted Indoles von Shen, Ming, Li, Guisheng, Lu, Bruce Z, Hossain, Azad, Roschangar, Frank, Farina, Vittorio, Senanayake, Chris H

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Nickel-catalyzed C-3 direct arylation of pyridinium ions for the synthesis of 1-azafluorenes von Desrosiers, Jean-Nicolas, Wei, Xudong, Gutierrez, Osvaldo, Savoie, Jolaine, Qu, Bo, Zeng, Xingzhong, Lee, Heewon, Grinberg, Nelu, Haddad, Nizar, Yee, Nathan K, Roschangar, Frank, Song, Jinhua J, Kozlowski, Marisa C, Senanayake, Chris H

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Zinc-Catalyzed Allenylations of Aldehydes and Ketones von Fandrick, Daniel R, Saha, Jaideep, Fandrick, Keith R, Sanyal, Sanjit, Ogikubo, Junichi, Lee, Heewon, Roschangar, Frank, Song, Jinhua J, Senanayake, Chris H

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A deeper shade of green: inspiring sustainable drug manufacturingElectronic supplementary information (ESI) available. See DOI: 10.1039/c6gc02901a von Roschangar, Frank, Colberg, Juan, Dunn, Peter J, Gallou, Fabrice, Hayler, John D, Koenig, Stefan G, Kopach, Michael E, Leahy, David K, Mergelsberg, Ingrid, Tucker, John L, Sheldon, Roger A, Senanayake, Chris H

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