The role of histone deacetylases (HDACs) in human cancer von Ropero, Santiago, Esteller, Manel

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microRNA DNA methylation signature for human cancer metastasis von Lujambio, Amaia, Calin, George A, Villanueva, Alberto, Ropero, Santiago, Sánchez-Céspedes, Montserrat, Blanco, David, Montuenga, Luis M, Rossi, Simona, Nicoloso, Milena S, Faller, William J, Gallagher, William M, Eccles, Suzanne A, Croce, Carlo M, Esteller, Manel

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A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells von Melo, Sonia A., Moutinho, Catia, Ropero, Santiago, Calin, George A., Rossi, Simona, Spizzo, Riccardo, Fernandez, Agustin F., Davalos, Veronica, Villanueva, Alberto, Montoya, Guillermo, Yamamoto, Hiroyuki, Schwartz, Simo, Esteller, Manel

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BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors von Veeck, Jurgen, Ropero, Santiago, Setien, Fernando, Gonzalez-Suarez, Eva, Osorio, Ana, Benitez, Javier, Herman, James G, Esteller, Manel

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Genetic unmasking of an epigenetically silenced microRNA in human cancer cells von LUJAMBIO, Amaia, ROPERO, Santiago, SPITERI, Inmaculada, DAS, Partha P, CALDAS, Carlos, MISKA, Eric, ESTELLER, Manel, BALLESTAR, Esteban, FRAGA, Mario F, CERRATO, Celia, SETIEN, Fernando, CASADO, Sara, SUAREZ-GAUTHIER, Ana, SANCHEZ-CESPEDES, Montserrat, GITT, Anna

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Epigenetic Differences Arise during the Lifetime of Monozygotic Twins von Fraga, Mario F., Ballestar, Esteban, Paz, Maria F., Ropero, Santiago, Setien, Fernando, Ballestar, Maria L., Heine-Suñer, Damia, Cigudosa, Juan C., Urioste, Miguel, Benitez, Javier, Boix-Chornet, Manuel, Sanchez-Aguilera, Abel, Ling, Charlotte, Carlsson, Emma, Poulsen, Pernille, Vaag, Allan, Stephan, Zarko, Spector, Tim D., Wu, Yue-Zhong, Plass, Christoph, Esteller, Manel, Gartler, Stanley M.

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Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing von Melo, Sonia, Villanueva, Alberto, Moutinho, Catia, Davalos, Veronica, Spizzo, Riccardo, Ivan, Cristina, Rossi, Simona, Setien, Fernando, Casanovas, Oriol, Simo-Riudalbas, Laia, Carmona, Javier, Carrere, Jordi, Vidal, August, Aytes, Alvaro, Puertas, Sara, Ropero, Santiago, Kalluri, Raghu, Croce, Carlo M, Calin, George A, Esteller, Manel

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Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma von Berdasco, María, Ropero, Santiago, Setien, Fernando, Fraga, Mario F, Lapunzina, Pablo, Losson, Régine, Alaminos, Miguel, Cheung, Nai-Kong, Rahman, Nazneen, Esteller, Manel

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A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function von Moutinho, Catia, Yamamoto, Hiroyuki, Capella, Gabriel, Ferreira, Bibiana, Liu, Chang-Gong, Esteller, Manel, Aaltonen, Lauri A, Shiekhattar, Ramin, Oliveira, Carla, Schwartz Jr, Simo, Ropero, Santiago, Rossi, Simona, Villanueva, Alberto, Calin, George A, Melo, Sonia A, Fernandez, Agustin F, Carneiro, Fatima

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer von Caldas, Carlos, Colomer, Dolors, Bonaldi, Tiziana, Lopez, Juan A, Iyer, N Gopalakrishna, Calasanz, Maria J, Pérez-Rosado, Alberto, Cano, Amparo, Ahn, Natalie, Jenuwein, Thomas, Ropero, Santiago, Boix-Chornet, Manuel, Calvo, Enrique, Haydon, Claire, Piris, Miguel Ángel, Esteller, Manel, Fraga, Mario F, Villar-Garea, Ana, Espada, Jesus, Petrie, Kevin, Imhof, Axel, Ballestar, Esteban, Schotta, Gunnar

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Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies von Taniguchi, Hiroaki, Fernández, Agustin F, Setién, Fernando, Ropero, Santiago, Ballestar, Esteban, Villanueva, Alberto, Yamamoto, Hiroyuki, Imai, Kohzoh, Shinomura, Yasuhisa, Esteller, Manel

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Claudin-3 Loss of Expression Is a Prognostic Marker in Castration-Resistant Prostate Cancer von Orea, María J, Angulo, Javier C, González-Corpas, Ana, Echegaray, David, Marvá, Marcos, Lobo, María V T, Colás, Begoña, Ropero, Santiago

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Inhibition of Fatty Acid Synthase (FAS) Suppresses HER2/Neu (ErbB-2) Oncogene Overexpression in Cancer Cells von Menendez, Javier A., Vellon, Luciano, Mehmi, Inderjit, Oza, Bharvi P., Ropero, Santiago, Colomer, Ramon, Lupu, Ruth, Gallo, Robert C.

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Discovery of Epigenetically Silenced Genes by Methylated DNA Immunoprecipitation in Colon Cancer Cells von JACINTO, Filipe V, BALLESTAR, Esteban, ROPERO, Santiago, ESTELLER, Manel

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A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition von Esteller, Manel, Ropero, Santiago, Fraga, Mario F, Ballestar, Esteban, Hamelin, Richard, Yamamoto, Hiroyuki, Boix-Chornet, Manuel, Caballero, Rosalia, Alaminos, Miguel, Setien, Fernando, Paz, Maria F, Herranz, Michel, Palacios, Jose, Arango, Diego, Orntoft, Torben F, Aaltonen, Lauri A, Schwartz, Simó

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Epigenetic Regulation of Gfi1 in Endocrine-Related Cancers: A Role Regulating Tumor Growth von Ashour, Nadia, Angulo, Javier C., Gonzalez-Corpas, Ana, Orea, Maria J., Lobo, Maria V. T., Colomer, Ramon, Colas, Begona, Esteller, Manel, Ropero, Santiago

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Epigenetic Inactivation of the Premature Aging Werner Syndrome Gene in Human Cancer von Agrelo, Ruben, Cheng, Wen-Hsing, Setien, Fernando, Ropero, Santiago, Espada, Jesus, Fraga, Mario F., Herranz, Michel, Paz, Maria F., Sanchez-Cespedes, Montserrat, Artiga, Maria Jesus, Guerrero, David, Castells, Antoni, von Kobbe, Cayetano, Bohr, Vilhelm A., Esteller, Manel

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A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors von FRAGA, Mario F, HERRANZ, Michel, MAO, Jian-Hua, BALMAIN, Alan, CANO, Amparo, ESTELLER, Manel, ESPADA, Jesus, BALLESTAR, Esteban, PAZ, Maria F, ROPERO, Santiago, ERKEK, Emel, BOZDOGAN, Onder, PEINADO, Héctor, NIVELEAU, Alain

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Epigenetics in Schizophrenia: A Pilot Study of Global DNA Methylation in Different Brain Regions Associated with Higher Cognitive Functions von Alelú-Paz, Raúl, Carmona, Francisco J, Sanchez-Mut, José V, Cariaga-Martínez, Ariel, González-Corpas, Ana, Ashour, Nadia, Orea, Maria J, Escanilla, Ana, Monje, Alfonso, Guerrero Márquez, Carmen, Saiz-Ruiz, Jerónimo, Esteller, Manel, Ropero, Santiago

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EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma von ALAMINOS, Miguel, DAVALOS, Veronica, ESTELLER, Manel, ROPERO, Santiago, SETIEN, Fernando, PAZ, Maria F, HERRANZ, Michel, FRAGA, Mario F, MORA, Jaume, CHEUNG, Nai-Kong V, GERALD, William L

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