Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor von Zaiss, Dietmar M.W., van Loosdregt, Jorg, Gorlani, Andrea, Bekker, Cornelis P.J., Gröne, Andrea, Sibilia, Maria, van Bergen en Henegouwen, Paul M.P., Roovers, Rob C., Coffer, Paul J., Sijts, Alice J.A.M.

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Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains von Schmitz, Karl R., Bagchi, Atrish, Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Ferguson, Kathryn M.

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ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding von Low-Nam, Shalini T, Lidke, Keith A, Cutler, Patrick J, Roovers, Rob C, van Bergen en Henegouwen, Paul M P, Wilson, Bridget S, Lidke, Diane S

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Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-Infrared Fluorescent Anti–Epidermal Growth Factor Receptor Nanobody von Oliveira, Sabrina, van Dongen, Guus A.M.S., Walsum, Marijke Stigter-van, Roovers, Rob C., Stam, Jord C., Mali, Willem, van Diest, Paul J., van Bergen en Henegouwen, Paul M.P.

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Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies von Stam, Jord C., de Maat, Steven, de Jong, Dorien, Arens, Mathia, van Lint, Fenna, Gharu, Lavina, van Roosmalen, Mark H., Roovers, Rob C., Strokappe, Nika M., Wagner, Ralf, Kliche, Alexander, de Haard, Hans J., van Bergen en Henegouwen, Paul M., Nijhuis, Monique, Verrips, C. Theo

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Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects von van de Water, Jeroen A. J. M, Bagci-Onder, Tugba, Agarwal, Aayush S, Wakimoto, Hiroaki, Roovers, Rob C, Zhu, Yanni, Kasmieh, Randa, Bhere, Deepak, Van Bergen en Henegouwen, Paul M. P, Shah, Khalid

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EGF induces coalescence of different lipid rafts von Hofman, Erik G, Ruonala, Mika O, Bader, Arjen N, van den Heuvel, Dave, Voortman, Jarno, Roovers, Rob C, Verkleij, Arie J, Gerritsen, Hans C, van Bergen en Henegouwen, Paul M.P

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Leveraging Vγ9Vδ2 T cells against prostate cancer through a VHH-based PSMA-Vδ2 bispecific T cell engager von King, Lisa A., Veth, Myrthe, Iglesias-Guimarais, Victoria, Blijdorp, Iris, Kloosterman, Jan, Vis, André N., Roovers, Rob C., Hulsik, David Lutje, Riedl, Thilo, Adang, Anton E.P., Parren, Paul W.H.I., van Helden, Pauline M., de Gruijl, Tanja D., van der Vliet, Hans J.

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Structural insights into the role and targeting of EGFRvIII von Bagchi, Atrish, Stayrook, Steven E., Xenaki, Katerina T., Starbird, Chrystal A., Doulkeridou, Sofia, el Khoulati, Rachid, Roovers, Rob C., Schmitz, Karl R., van Bergen en Henegouwen, Paul M.P., Ferguson, Kathryn M.

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A biparatopic anti‐EGFR nanobody efficiently inhibits solid tumour growth von Roovers, Rob C., Vosjan, Maria J.W.D., Laeremans, Toon, el Khoulati, Rachid, de Bruin, Renée C.G., Ferguson, Kathryn M., Verkleij, Arie J., van Dongen, Guus A.M.S., van Bergen en Henegouwen, Paul M.P.

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Targeting hepatocyte growth factor receptor (Met) positive tumor cells using internalizing nanobody-decorated albumin nanoparticles von Heukers, Raimond, Altintas, Isil, Raghoenath, Smiriti, De Zan, Erica, Pepermans, Richard, Roovers, Rob C, Haselberg, Rob, Hennink, Wim E, Schiffelers, Raymond M, Kok, Robbert J, van Bergen en Henegouwen, Paul M.P

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Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors von Herpers, Bram, Eppink, Berina, James, Mark I, Cortina, Carme, Cañellas-Socias, Adrià, Boj, Sylvia F, Hernando-Momblona, Xavier, Glodzik, Dominik, Roovers, Rob C, van de Wetering, Marc, Bartelink-Clements, Carina, Zondag-van der Zande, Vanessa, Mateos, Jara García, Yan, Kuan, Salinaro, Lucia, Basmeleh, Abdul, Fatrai, Szabolcs, Maussang, David, Lammerts van Bueren, Jeroen J, Chicote, Irene, Serna, Garazi, Cabellos, Laia, Ramírez, Lorena, Nuciforo, Paolo, Salazar, Ramon, Santos, Cristina, Villanueva, Alberto, Stephan-Otto Attolini, Camille, Sancho, Elena, Palmer, Hector G, Tabernero, Josep, Stratton, Michael R, de Kruif, John, Logtenberg, Ton, Clevers, Hans, Price, Leo S, Vries, Robert G J, Batlle, Eduard, Throsby, Mark

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Downregulation of EGFR by a novel multivalent nanobody-liposome platform von Oliveira, Sabrina, Schiffelers, Raymond M., van der Veeken, Joris, van der Meel, Roy, Vongpromek, Ranitha, van Bergen en Henegouwen, Paul M.P., Storm, Gert, Roovers, Rob C.

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Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies von Roovers, Rob C., Laeremans, Toon, Huang, Lieven, De Taeye, Severine, Verkleij, Arie J., Revets, Hilde, de Haard, Hans J., van Bergen en Henegouwen, Paul M. P.

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A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies von de Weerdt, Iris, Lameris, Roeland, Scheffer, George L, Vree, Jana, de Boer, Renate, Stam, Anita G, van de Ven, Rieneke, Levin, Mark-David, Pals, Steven T, Roovers, Rob C, Parren, Paul W H I, de Gruijl, Tanja D, Kater, Arnon P, van der Vliet, Hans J

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Tumor-targeted Nanobullets: Anti-EGFR nanobody-liposomes loaded with anti-IGF-1R kinase inhibitor for cancer treatment von van der Meel, Roy, Oliveira, Sabrina, Altintas, Isil, Haselberg, Rob, van der Veeken, Joris, Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Storm, Gert, Hennink, Wim E., Schiffelers, Raymond M., Kok, Robbert J.

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Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform von Klarenbeek, Alex, Mazouari, Khalil El, Desmyter, Aline, Blanchetot, Christophe, Hultberg, Anna, de Jonge, Natalie, Roovers, Rob C, Cambillau, Christian, Spinelli, Sylvia, Del-Favero, Jurgen, Verrips, Theo, de Haard, Hans J, Achour, Ikbel

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Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif von Heukers, Raimond, Vermeulen, Jeroen F, Fereidouni, Farzad, Bader, Arjen N, Voortman, Jarno, Roovers, Rob C, Gerritsen, Hans C, van Bergen En Henegouwen, Paul M P

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A bispecific T cell engager recruits both type 1 NKT and Vγ9Vδ2-T cells for the treatment of CD1d-expressing hematological malignancies von Lameris, Roeland, Ruben, Jurjen M., Iglesias-Guimarais, Victoria, de Jong, Milon, Veth, Myrthe, van de Bovenkamp, Fleur S., de Weerdt, Iris, Kater, Arnon P., Zweegman, Sonja, Horbach, Sjeng, Riedl, Thilo, Winograd, Benjamin, Roovers, Rob C., Adang, Anton E.P., de Gruijl, Tanja D., Parren, Paul W.H.I., van der Vliet, Hans J.

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A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells von de Bruin, Renée C. G., Veluchamy, John P., Lougheed, Sinéad M., Schneiders, Famke L., Lopez-Lastra, Silvia, Lameris, Roeland, Stam, Anita G., Sebestyen, Zsolt, Kuball, Jürgen, Molthoff, Carla F. M., Hooijberg, Erik, Roovers, Rob C., Santo, James P. Di, van Bergen en Henegouwen, Paul M. P., Verheul, Henk M. W., de Gruijl, Tanja D., van der Vliet, Hans J.

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