Obstructive Sleep Apnea is Linked to Depression and Cognitive Impairment: Evidence and Potential Mechanisms von Kerner, Nancy A., M.D, Roose, Steven P., M.D

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Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases von Kondo, Yasushi, Ognjenović, Jana, Banerjee, Saikat, Karandur, Deepti, Merk, Alan, Kulhanek, Kayla, Wong, Kathryn, Roose, Jeroen P, Subramaniam, Sriram, Kuriyan, John

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RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma von Chen, Xu, Wu, Qiuxia, Depeille, Philippe, Chen, Peirong, Thornton, Sophie, Kalirai, Helen, Coupland, Sarah E., Roose, Jeroen P., Bastian, Boris C.

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Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo von Miao, Yi, Ha, Andrew, de Lau, Wim, Yuki, Kanako, Santos, António J.M., You, Changjiang, Geurts, Maarten H., Puschhof, Jens, Pleguezuelos-Manzano, Cayetano, Peng, Weng Chuan, Senlice, Ramazan, Piani, Carol, Buikema, Jan W., Gbenedio, Oghenekevwe M., Vallon, Mario, Yuan, Jenny, de Haan, Sanne, Hemrika, Wieger, Rösch, Kathrin, Dang, Luke T., Baker, David, Ott, Melanie, Depeille, Philippe, Wu, Sean M., Drost, Jarno, Nusse, Roeland, Roose, Jeroen P., Piehler, Jacob, Boj, Sylvia F., Janda, Claudia Y., Clevers, Hans, Kuo, Calvin J., Garcia, K. Christopher

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A Meta-Analysis of Executive Dysfunction and Antidepressant Treatment Response in Late-Life Depression von Pimontel, Monique A., M.A, Rindskopf, David, Ph.D, Rutherford, Bret R., M.D, Brown, Patrick J., Ph.D, Roose, Steven P., M.D, Sneed, Joel R., Ph.D

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Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells von Myers, Darienne R., Norlin, Emilia, Vercoulen, Yvonne, Roose, Jeroen P.

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The Depressed Frail Phenotype: The Clinical Manifestation of Increased Biological Aging von Brown, Patrick J., Ph.D, Rutherford, Bret R., M.D, Yaffe, Kristine, M.D, Tandler, Jane M., B.A, Ray, Justina Laurence, B.A, Pott, Emily, B.S, Chung, Sarah, B.A, Roose, Steven P., M.D

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RasGRP1 opposes proliferative EGFR–SOS1–Ras signals and restricts intestinal epithelial cell growth von Depeille, Philippe, Henricks, Linda M., van de Ven, Robert A. H., Lemmens, Ed, Wang, Chih-Yang, Matli, Mary, Werb, Zena, Haigis, Kevin M., Donner, David, Warren, Robert, Roose, Jeroen P.

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Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life von Brown, Patrick J, Roose, Steven P, Zhang, Jun, Wall, Melanie, Rutherford, Bret R, Ayonayon, Hilsa N, Butters, Meryl A, Harris, Tamara, Newman, Anne B, Satterfield, Suzanne, Simonsick, Eleanor M, Yaffe, Kristine

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Frailty and Depression in Older Adults: A High-Risk Clinical Population von Brown, Patrick J., Ph.D, Roose, Steven P., M.D, Fieo, Robert, Ph.D, Liu, Xinhua, Ph.D, Rantanen, Taina, Ph.D, Sneed, Joel R., Ph.D, Rutherford, Bret R., M.D, Devanand, D.P., M.D, Avlund, Kirsten, Ph.D

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Unusual Interplay of Two Types of Ras Activators, RasGRP and SOS, Establishes Sensitive and Robust Ras Activation in Lymphocytes von Roose, Jeroen P., Mollenauer, Marianne, Ho, Mary, Kurosaki, Tomohiro, Weiss, Arthur

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A Quality-Based Review of Randomized Controlled Trials of Psychodynamic Psychotherapy von Gerber, Andrew J., Kocsis, James H., Milrod, Barbara L., Roose, Steven P., Barber, Jacques P., Thase, Michael E., Perkins, Patrick, Leon, Andrew C.

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Sensation and Psychiatry: Linking Age-Related Hearing Loss to Late-Life Depression and Cognitive Decline von Rutherford, Bret R, Brewster, Katharine, Golub, Justin S, Kim, Ana H, Roose, Steven P

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Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy von Ksionda, Olga, Mues, Marsilius, Wandler, Anica M, Donker, Lisa, Tenhagen, Milou, Jun, Jesse, Ducker, Gregory S, Matlawska-Wasowska, Ksenia, Shannon, Kevin, Shokat, Kevan M, Roose, Jeroen P

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Not Just Nonspecific Factors: The Roles of Alliance and Expectancy in Treatment, and Their Neurobiological Underpinnings von Zilcha-Mano, Sigal, Roose, Steven P, Brown, Patrick J, Rutherford, Bret R

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NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids von Simoneau, Camille R., Chen, Pei-Yi, Xing, Galen K., Hayashi, Jennifer M., Chen, Irene P., Khalid, Mir M., Meyers, Nathan L., Taha, Taha Y., Leon, Kristoffer E., Suryawanshi, Rahul K., McCavitt-Malvido, Maria, Ashuach, Tal, Fontaine, Krystal A., Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Vasudevan, Sreelakshmi, Fang, Xiaohui, Maishan, Mazharul, Schultz, Shawn, Roose, Jeroen P., Matthay, Michael A., Sil, Anita, Arjomandi, Mehrdad, Yosef, Nir, Ott, Melanie

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Age and anxiety and depressive symptoms: the effect on domains of quality of life von Brown, Patrick J., Roose, Steven P.

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RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines von Ksionda, O, Melton, A A, Bache, J, Tenhagen, M, Bakker, J, Harvey, R, Winter, S S, Rubio, I, Roose, J P

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A Model of Placebo Response in Antidepressant Clinical Trials von Rutherford, Bret R., Roose, Steven P.

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Tonic Signals: Why Do Lymphocytes Bother? von Myers, Darienne R., Zikherman, Julie, Roose, Jeroen P.

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