Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models von Wen, Li, Voronina, Svetlana, Javed, Muhammad A, Awais, Muhammad, Szatmary, Peter, Latawiec, Diane, Chvanov, Michael, Collier, David, Huang, Wei, Barrett, John, Begg, Malcolm, Stauderman, Ken, Roos, Jack, Grigoryev, Sergey, Ramos, Stephanie, Rogers, Evan, Whitten, Jeff, Velicelebi, Gonul, Dunn, Michael, Tepikin, Alexei V, Criddle, David N, Sutton, Robert

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The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis von Waldron, Richard T., Chen, Yafeng, Pham, Hung, Go, Ariel, Su, Hsin‐Yuan, Hu, Cheng, Wen, Li, Husain, Sohail Z., Sugar, Catherine A., Roos, Jack, Ramos, Stephanie, Lugea, Aurelia, Dunn, Michael, Stauderman, Kenneth, Pandol, Stephen J.

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Cumulative review of hypertension in patients with chronic lymphocytic leukemia treated with acalabrutinib von Ferrajoli, Alessandra, Follows, George, Marmor, Yotvat, Roos, Jack, Bajwa, Naghmana, Madhira, Venkata, Nozaki, Kenji, Miranda, Paulo, Pennap, Dinci, Patel, Krish

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Genome-wide RNAi screen of Ca2+ influx identifies genes that regulate Ca2+ release-activated Ca2+ channel activity von Zhang, S., Yeromin, A., Zhang, X. H.-F., Yu, Y., Safrina, O., Penna, A., Roos, J., Stauderman, K., Cahalan, M.

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STIM1, an essential and conserved component of store-operated Ca²⁺ channel function von Roos, Jack, DiGregorio, Paul J, Yeromin, Andriy V, Ohlsen, Kari, Lioudyno, Maria, Zhang, Shenyuan, Safrina, Olga, Kozak, J. Ashot, Wagner, Steven L, Cahalan, Michael D, Veliçelebi, Gönůl, Stauderman, Kenneth A

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Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation von Lioudyno, Maria I, Kozak, J. Ashot, Penna, Aubin, Safrina, Olga, Zhang, Shenyuan L, Sen, Debasish, Roos, Jack, Stauderman, Kenneth A, Cahalan, Michael D

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Drosophila Futsch/22C10 Is a MAP1B-like Protein Required for Dendritic and Axonal Development von Hummel, Thomas, Krukkert, Karin, Roos, Jack, Davis, Graeme, Klämbt, Christian

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Synaptojanin Is Recruited by Endophilin to Promote Synaptic Vesicle Uncoating von Verstreken, Patrik, Koh, Tong-Wey, Schulze, Karen L., Zhai, R.Grace, Hiesinger, P.Robin, Zhou, Yi, Mehta, Sunil Q., Cao, Yu, Roos, Jack, Bellen, Hugo J.

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Dap160/Intersectin Scaffolds the Periactive Zone to Achieve High-Fidelity Endocytosis and Normal Synaptic Growth von Marie, Bruno, Sweeney, Sean T, Poskanzer, Kira E, Roos, Jack, Kelly, Regis B, Davis, Graeme W

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Drosophila Futsch Regulates Synaptic Microtubule Organization and Is Necessary for Synaptic Growth von Roos, Jack, Hummel, Thomas, Ng, Norman, Klämbt, Christian, Davis, Graeme W.

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The endocytic machinery in nerve terminals surrounds sites of exocytosis von Roos, Jack, Kelly, Regis B.

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P642: A MATCHING‐ADJUSTED INDIRECT COMPARISON OF THE EFFICACY AND SAFETY OF ACALABRUTINIB VERSUS ZANUBRUTINIB IN RELAPSED OR REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA von Skarbnik, Alan, Kittai, Adam, Miranda, Miguel, Yong, Alan, Roos, Jack, Hettle, Robert, Palazuelos‐Munoz, Sarah, Shetty, Vikram, Ghia, Paolo

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Acrue: A Phase 2, Open-Label Study of Acalabrutinib in Combination with Rituximab in Elderly and/or Frail Patients with Treatment-Naive Diffuse Large B-Cell Lymphoma von Perini, Guilherme F, Graff, Tara, Roos, Jack, Hermann, Richard, Lovenklev, Magnus, Shaw, Bob, Budde, L. Elizabeth

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A store-operated calcium channel in Drosophila S2 cells von Yeromin, Andriy V, Roos, Jack, Stauderman, Kenneth A, Cahalan, Michael D

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Matching-Adjusted Indirect Comparisons of the Efficacy and Safety of Acalabrutinib Versus Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma von Gaitonde, Priyanka, Cai, Ling, de Miranda, Paulo, Roos, Jack, Rule, Simon, Wang, Michael L.

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ABCL-192 ACRUE: A Phase 2, Open-Label Study of Acalabrutinib in Combination With Rituximab in Elderly and/or Frail Patients With Treatment-Naive Diffuse Large B-Cell Lymphoma von Perini, Guilherme F., Graff, Tara, Roos, Jack, Hermann, Richard, Lovenklev, Magnus, Shaw, Bob, Budde, Lihua E.

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Cumulative Review of Hypertension in Patients with Chronic Lymphocytic Leukemia (CLL) and Other Hematologic Malignancies Treated with Acalabrutinib von Ferrajoli, Alessandra, Follows, George, Marmor, Yotvat, Bourjlian, Shogheeg Apkarian, Roos, Jack, Bajwa, Naghmana, Madhira, Venkata, Nozaki, Kenji, Palhares De Miranda, Paulo Andre P., Patel, Krish

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A Matching-Adjusted Indirect Comparison of Acalabrutinib with and without Obinutuzumab Versus Zanubrutinib in Treatment-Naïve Chronic Lymphocytic Leukemia von Allan, John N., Kittai, Adam S, James, Dan, Ridge, Helen, Miranda, Miguel, Yong, Alan, Fam, Fady, Roos, Jack, Shetty, Vikram, Davids, Matthew S., Skarbnik, Alan

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A matching-adjusted indirect comparison (MAIC) of the efficacy and safety of acalabrutinib (acala) versus zanubrutinib (zanu) in relapsed or refractory chronic lymphocytic leukemia... von Kittai, Adam, Skarbnik, Alan, Miranda, Miguel, Yong, Alan SM, Roos, Jack, Hettle, Robert, Palazuelos-Munoz, Sarah, Shetty, Vikram, Ghia, Paolo

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane von Zhang, Shenyuan L., Yu, Ying, Roos, Jack, Kozak, J. Ashot, Deerinck, Thomas J., Ellisman, Mark H., Stauderman, Kenneth A., Cahalan, Michael D.

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