FcRn: the neonatal Fc receptor comes of age von Roopenian, Derry C, Akilesh, Shreeram

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Inhibition of Glycolysis Reduces Disease Severity in an Autoimmune Model of Rheumatoid Arthritis von Abboud, Georges, Choi, Seung-Chul, Kanda, Nathalie, Zeumer-Spataro, Leilani, Roopenian, Derry C, Morel, Laurence

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Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells von Choi, Seung-Chul, Titov, Anton A., Abboud, Georges, Seay, Howard R., Brusko, Todd M., Roopenian, Derry C., Salek-Ardakani, Shahram, Morel, Laurence

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Seven naturally variant loci serve as genetic modifiers of Lamc2jeb induced non-Herlitz junctional Epidermolysis Bullosa in mice von Sproule, Thomas J, Philip, Vivek M, Chaudhry, Nabig A, Roopenian, Derry C, Sundberg, John P

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Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies von Proetzel, Gabriele, Roopenian, Derry C.

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Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice von Sproule, Thomas J, Wilpan, Robert Y, Low, Benjamin E, Silva, Kathleen A, Reyon, Deepak, Joung, J Keith, Wiles, Michael V, Roopenian, Derry C, Sundberg, John P

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Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection von Li, Zili, Palaniyandi, Senthilkumar, Zeng, Rongyu, Tuo, Wenbin, Roopenian, Derry C, Zhu, Xiaoping

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Enhanced antibody half-life improves in vivo activity von Karki, Sher, Leung, Irene W L, Horton, Holly M, Chamberlain, Aaron K, Roopenian, Derry C, Desjarlais, John R, Lazar, Greg A, Zalevsky, Jonathan, Sproule, Thomas J

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CD8⁺ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice von Kim, Hye-Jung, Wang, Xuan, Radfar, Soroosh, Sproule, Thomas J, Roopenian, Derry C, Cantor, Harvey

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Coronary artery disease from isolated non-H2-determined incompatibilities in transplanted mouse hearts von Russell, Paul S, Chase, Catharine M, Madsen, Joren C, Hirohashi, Tsutomu, Cornell, Lynn D, Sproule, Thomas J, Colvin, Robert B, Roopenian, Derry C

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critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice von Bubier, Jason A, Sproule, Thomas J, Foreman, Oded, Spolski, Rosanne, Shaffer, Daniel J, Morse, Herbert C. III, Leonard, Warren J, Roopenian, Derry C

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Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease von Petkova, Stefka B., Akilesh, Shreeram, Sproule, Thomas J., Christianson, Gregory J., Al Khabbaz, Hana, Brown, Aaron C., Presta, Leonard G., Meng, Y. Gloria, Roopenian, Derry C.

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An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics von Bern, Malin C, Nilsen, Jeannette, Ferrarese, Mattia, Sand, Kine Marita Knudsen, Tollefsrud Gjølberg, Torleif, Lode, Heidrun Elisabeth, Davidson, Robert J, Camire, Rodney M, Bækkevold, Espen Sønderaal, Foss, Stian, Grevys, Algirdas, Dalhus, Bjørn, Wilson, John, Høydahl, Lene, Christianson, Gregory J, Roopenian, Derry C, Schlothauer, Tilman, Michaelsen, Terje Einar, Moe, Morten Carsten, Lombardi, Silvia, Pinotti, Mirko, Sandlie, Inger, Branchini, Alessio, Andersen, Jan Terje

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Neonatal FcR Expression in Bone Marrow-Derived Cells Functions to Protect Serum IgG from Catabolism von Akilesh, Shreeram, Christianson, Gregory J, Roopenian, Derry C, Shaw, Andrey S

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Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury von Pyzik, Michal, Rath, Timo, Kuo, Timothy T., Win, Sanda, Baker, Kristi, Hubbard, Jonathan J., Grenha, Rosa, Gandhi, Amit, Krämer, Thomas D., Mezo, Adam R., Taylor, Zachary S., McDonnell, Kevin, Nienaber, Vicki, Andersen, Jan Terje, Mizoguchi, Atsushi, Blumberg, Laurence, Purohit, Shalaka, Jones, Susan D., Christianson, Greg, Lencer, Wayne I., Sandlie, Inger, Kaplowitz, Neil, Roopenian, Derry C., Blumberg, Richard S.

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Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum von Sproule, Thomas J, Wilpan, Robert Y, Wilson, John J, Low, Benjamin E, Kabata, Yudai, Ushiki, Tatsuo, Abe, Riichiro, Wiles, Michael V, Roopenian, Derry C, Sundberg, John P

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Efficient mucosal vaccination mediated by the neonatal Fc receptor von Zhu, Xiaoping, Ye, Lilin, Zeng, Rongyu, Bai, Yu, Roopenian, Derry C

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A human endothelial cell-based recycling assay for screening of FcRn targeted molecules von Grevys, Algirdas, Nilsen, Jeannette, Sand, Kine M. K., Daba, Muluneh B., Øynebråten, Inger, Bern, Malin, McAdam, Martin B., Foss, Stian, Schlothauer, Tilman, Michaelsen, Terje E., Christianson, Gregory J., Roopenian, Derry C., Blumberg, Richard S., Sandlie, Inger, Andersen, Jan Terje

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Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice von Wells, Ann E, Wilson, John J, Heuer, Sarah E, Sears, John D, Wei, Jian, Pandey, Raghav, Costa, Mauro W, Kaczorowski, Catherine C, Roopenian, Derry C, Chang, Chih-Hao, Carter, Gregory W

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A Neonatal Fc Receptor-Targeted Mucosal Vaccine Strategy Effectively Induces HIV-1 Antigen-Specific Immunity to Genital Infection von LI LU, PALANIYANDI, Senthilkumar, RONGYU ZENG, YU BAI, XINDONG LIU, YUNSHENG WANG, DAVID PAUZA, C, ROOPENIAN, Derry C, XIAOPING ZHU

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