Advances in the biology and treatment of bone disease in multiple myeloma von Raje, Noopur, Roodman, G David

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Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3 von Hiasa, Masahiro, Okui, Tatsuo, Allette, Yohance M, Ripsch, Matthew S, Sun-Wada, Ge-Hong, Wakabayashi, Hiroki, Roodman, G David, White, Fletcher A, Yoneda, Toshiyuki

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EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation von Adamik, Juraj, Jin, Shunqian, Sun, Quanhong, Zhang, Peng, Weiss, Kurt R, Anderson, Judith L, Silbermann, Rebecca, Roodman, G David, Galson, Deborah L

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Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma von Delgado-Calle, Jesus, Anderson, Judith, Cregor, Meloney D, Hiasa, Masahiro, Chirgwin, John M, Carlesso, Nadia, Yoneda, Toshiyuki, Mohammad, Khalid S, Plotkin, Lilian I, Roodman, G David, Bellido, Teresita

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Role of Bone-Modifying Agents in Multiple Myeloma: American Society of Clinical Oncology Clinical Practice Guideline Update von Anderson, Kenneth, Ismaila, Nofisat, Flynn, Patrick J, Halabi, Susan, Jagannath, Sundar, Ogaily, Mohammed S, Omel, Jim, Raje, Noopur, Roodman, G David, Yee, Gary C, Kyle, Robert A

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Multiple myeloma bone disease: pathophysiology of osteoblast inhibition von Giuliani, Nicola, Rizzoli, Vittorio, Roodman, G. David

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A novel role of IL-17–producing lymphocytes in mediating lytic bone disease in multiple myeloma von Noonan, Kimberly, Marchionni, Luigi, Anderson, Judy, Pardoll, Drew, Roodman, G. David, Borrello, Ivan

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International Myeloma Working Group Recommendations for the Treatment of Multiple Myeloma–Related Bone Disease von TERPOS, Evangelos, MORGAN, Gareth, REIMAN, Tony, JURCZYSZYN, Artur, MERLINI, Giampaolo, SPENCER, Andrew, LELEU, Xavier, CAVO, Michele, MUNSHI, Nikhil, VINCENT RAJKUMAR, S, DURIE, Brian G. M, ROODMAN, G. David, DIMOPOULOS, Meletios A, DRAKE, Matthew T, LENTZSCH, Suzanne, RAJE, Noopur, SEZER, Orhan, GARCIA-SANZ, Ramón, SHIMIZU, Kazuyuki, TURESSON, Ingemar

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Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction von Storti, P, Bolzoni, M, Donofrio, G, Airoldi, I, Guasco, D, Toscani, D, Martella, E, Lazzaretti, M, Mancini, C, Agnelli, L, Patrene, K, Maïga, S, Franceschi, V, Colla, S, Anderson, J, Neri, A, Amiot, M, Aversa, F, David Roodman, G, Giuliani, N

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Regulation of Osteoclast Differentiation von ROODMAN, G. DAVID

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Increased S1P expression in osteoclasts enhances bone formation in an animal model of Paget's disease von Nagata, Yuki, Miyagawa, Kazuaki, Ohata, Yasuhisa, Petrusca, Daniela N., Pagnotti, Gabriel M., Mohammad, Khalid S., Guise, Theresa A., Windle, Jolene J., David Roodman, G., Kurihara, Noriyoshi

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Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity von Sabol, Hayley M, Ferrari, Adam J, Adhikari, Manish, Amorim, Tânia, McAndrews, Kevin, Anderson, Judith, Vigolo, Michele, Lehal, Rajwinder, Cregor, Meloney, Khan, Sharmin, Cuevas, Pedro L, Helms, Jill A, Kurihara, Noriyoshi, Srinivasan, Venkat, Ebetino, Frank H, Boeckman, Jr, Robert K, Roodman, G David, Bellido, Teresita, Delgado-Calle, Jesus

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Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation von Xu, Guoshuang, Liu, Kai, Anderson, Judy, Patrene, Kenneth, Lentzsch, Suzanne, Roodman, G. David, Ouyang, Hongjiao

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Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma von Silbermann, R, Bolzoni, M, Storti, P, Guasco, D, Bonomini, S, Zhou, D, Wu, J, Anderson, J L, Windle, J J, Aversa, F, David Roodman, G, Giuliani, N

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Notch3 signaling between myeloma cells and osteocytes in the tumor niche promotes tumor growth and bone destruction von Sabol, Hayley M., Amorim, Tânia, Ashby, Cody, Halladay, David, Anderson, Judith, Cregor, Meloney, Sweet, Megan, Nookaew, Intawat, Kurihara, Noriyoshi, Roodman, G. David, Bellido, Teresita, Delgado-Calle, Jesus

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Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ES... von Hadji, Peyman, Aapro, Matti S., Body, Jean-Jacques, Gnant, Michael, Brandi, Maria Luisa, Reginster, Jean Yves, Zillikens, M. Carola, Glüer, Claus-C., de Villiers, Tobie, Baber, Rod, Roodman, G. David, Cooper, Cyrus, Langdahl, Bente, Palacios, Santiago, Kanis, John, Al-Daghri, Nasser, Nogues, Xavier, Eriksen, Erik Fink, Kurth, Andreas, Rizzoli, Rene, Coleman, Robert E.

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Pharmacologic targeting of the p62 ZZ domain enhances both anti-tumor and bone-anabolic effects of bortezomib in multiple myeloma von Marino, Silvia, Petrusca, Daniela N, Bishop, Ryan T, Anderson, Judith L, Sabol, Hayley M, Ashby, Cody, Layer, Justin H, Cesarano, Annamaria, Davé, Utpal P, Perna, Fabiana, Delgado-Calle, Jesus, Chirgwin, John M, Roodman, G David

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Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23 von Mulcrone, Patrick L., Edwards, Shanique K. E., Petrusca, Daniela N., Haneline, Laura S., Delgado-Calle, Jesús, Roodman, G. David

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The role of cement augmentation with percutaneous vertebroplasty and balloon kyphoplasty for the treatment of vertebral compression fractures in multiple myeloma: a consensus state... von Kyriakou, Charalampia, Molloy, Sean, Vrionis, Frank, Alberico, Ronald, Bastian, Leonard, Zonder, Jeffrey A., Giralt, Sergio, Raje, Noopur, Kyle, Robert A., Roodman, David G. D., Dimopoulos, Meletios A., Rajkumar, S. Vincent, Durie, Brian B. G., Terpos, Evangelos

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In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2 von Maes, Ken, Nemeth, Elizabeta, Roodman, G. David, Huston, Alissa, Esteve, Flavia, Freytes, Cesar, Callander, Natalie, Katodritou, Eirini, Tussing-Humphreys, Lisa, Rivera, Seth, Vanderkerken, Karin, Lichtenstein, Alan, Ganz, Tomas

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