Choline metabolism in malignant transformation von Glunde, Kristine, Bhujwalla, Zaver M., Ronen, Sabrina M.

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Protein and Nucleotide Biosynthesis Are Coupled by a Single Rate-Limiting Enzyme, PRPS2, to Drive Cancer von Cunningham, John T., Moreno, Melissa V., Lodi, Alessia, Ronen, Sabrina M., Ruggero, Davide

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Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation von Lock, Rebecca, Roy, Srirupa, Kenific, Candia M, Su, Judy S, Salas, Eduardo, Ronen, Sabrina M, Debnath, Jayanta

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Metabolic reprogramming in mutant IDH1 glioma cells von Izquierdo-Garcia, Jose L, Viswanath, Pavithra, Eriksson, Pia, Chaumeil, Myriam M, Pieper, Russell O, Phillips, Joanna J, Ronen, Sabrina M

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Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis von Johannessen, Tor-Christian Aase, Mukherjee, Joydeep, Viswanath, Pavithra, Ohba, Shigeo, Ronen, Sabrina M, Bjerkvig, Rolf, Pieper, Russell O

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Gene Expression Profile Identifies Tyrosine Kinase c-Met as a Targetable Mediator of Antiangiogenic Therapy Resistance von JAHANGIRI, Arman, DE LAY, Michael, MARSHALL, Roxanne, PERRY, Arie, BJORGAN, Kirsten M, CHAUMEIL, Myriam M, RONEN, Sabrina M, BERGERS, Gabriele, AGHI, Manish K, MILLER, Liane M, CARBONELL, W. Shawn, HU, Yu-Long, KAN LU, TOM, Maxwell W, PAQUETTE, Jesse, TOKUYASU, Taku A, TSAO, Sean

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IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism von Izquierdo-Garcia, Jose L, Viswanath, Pavithra, Eriksson, Pia, Cai, Larry, Radoul, Marina, Chaumeil, Myriam M, Blough, Michael, Luchman, H Artee, Weiss, Samuel, Cairncross, J Gregory, Phillips, Joanna J, Pieper, Russell O, Ronen, Sabrina M

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Magnetic resonance spectroscopy detectable metabolomic fingerprint of response to antineoplastic treatment von Lodi, Alessia, Ronen, Sabrina M

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2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas von Viswanath, Pavithra, Radoul, Marina, Izquierdo-Garcia, Jose Luis, Ong, Wei Qiang, Luchman, Hema Artee, Cairncross, J Gregory, Huang, Bo, Pieper, Russell O, Phillips, Joanna J, Ronen, Sabrina M

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Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma von Mukherjee, Joydeep, Phillips, Joanna J, Zheng, Shichun, Wiencke, John, Ronen, Sabrina M, Pieper, Russell O

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Non-invasive assessment of telomere maintenance mechanisms in brain tumors von Viswanath, Pavithra, Batsios, Georgios, Mukherjee, Joydeep, Gillespie, Anne Marie, Larson, Peder E. Z., Luchman, H. Artee, Phillips, Joanna J., Costello, Joseph F., Pieper, Russell O., Ronen, Sabrina M.

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Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma von Jalbert, Llewellyn E., Elkhaled, Adam, Phillips, Joanna J., Neill, Evan, Williams, Aurelia, Crane, Jason C., Olson, Marram P., Molinaro, Annette M., Berger, Mitchel S., Kurhanewicz, John, Ronen, Sabrina M., Chang, Susan M., Nelson, Sarah J.

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Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells von Park, Ilwoo, Mukherjee, Joydeep, Ito, Motokazu, Chaumeil, Myriam M, Jalbert, Llewellyn E, Gaensler, Karin, Ronen, Sabrina M, Nelson, Sarah J, Pieper, Russell O

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Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma von Minami, Noriaki, Hong, Donghyun, Taglang, Celine, Batsios, Georgios, Gillespie, Anne Marie, Viswanath, Pavithra, Stevers, Nicholas, Barger, Carter J., Costello, Joseph F., Ronen, Sabrina M.

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Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase von Izquierdo-Garcia, Jose L, Cai, Larry M, Chaumeil, Myriam M, Eriksson, Pia, Robinson, Aaron E, Pieper, Russell O, Phillips, Joanna J, Ronen, Sabrina M

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Hyperpolarized [1-13C] Glutamate: A Metabolic Imaging Biomarker of IDH1 Mutational Status in Glioma von CHAUMEIL, Myriam M, LARSON, Peder E. Z, PHILLIPS, Joanna J, RONEN, Sabrina M, WOODS, Sarah M, CAI, Larry, ERIKSSON, Pia, ROBINSON, Aaron E, LUPO, Janine M, VIGNERON, Daniel B, NELSON, Sarah J, PIEPER, Russell O

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Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process von Ohba, Shigeo, Mukherjee, Joydeep, Johannessen, Tor-Christian, Mancini, Andrew, Chow, Tracy T, Wood, Matthew, Jones, Lindsey, Mazor, Tali, Marshall, Roxanne E, Viswanath, Pavithra, Walsh, Kyle M, Perry, Arie, Bell, Robert J A, Phillips, Joanna J, Costello, Joseph F, Ronen, Sabrina M, Pieper, Russell O

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Early Chk1 phosphorylation is driven by temozolomide-induced, DNA double strand break- and mismatch repair-independent DNA damage von Ito, Motokazu, Ohba, Shigeo, Gaensler, Karin, Ronen, Sabrina M, Mukherjee, Joydeep, Pieper, Russell O

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HDAC inhibition induces increased choline uptake and elevated phosphocholine levels in MCF7 breast cancer cells von Ward, Christopher S, Eriksson, Pia, Izquierdo-Garcia, Jose L, Brandes, Alissa H, Ronen, Sabrina M

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Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake von Roy, Srirupa, Leidal, Andrew M., Ye, Jordan, Ronen, Sabrina M., Debnath, Jayanta

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