Ubiquitin ligases in oncogenic transformation and cancer therapy von Senft, Daniela, Qi, Jianfei, Ronai, Ze'ev A.

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Regulators of mitochondrial dynamics in cancer von Senft, Daniela, Ronai, Ze’ev A

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Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia von Kim, Hyungsoo, Scimia, Maria C., Wilkinson, Deepti, Trelles, Ramon D., Wood, Malcolm R., Bowtell, David, Dillin, Andrew, Mercola, Mark, Ronai, Ze'ev A.

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The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors von Khateb, Ali, Deshpande, Anagha, Feng, Yongmei, Finlay, Darren, Lee, Joo Sang, Lazar, Ikrame, Fabre, Bertrand, Li, Yan, Fujita, Yu, Zhang, Tongwu, Yin, Jun, Pass, Ian, Livneh, Ido, Jeremias, Irmela, Burian, Carol, Mason, James R., Almog, Ronit, Horesh, Nurit, Ofran, Yishai, Brown, Kevin, Vuori, Kristiina, Jackson, Michael, Ruppin, Eytan, Deshpande, Aniruddha J., Ronai, Ze’ev A.

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Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons von Welsbie, Derek S., Mitchell, Katherine L., Jaskula-Ranga, Vinod, Sluch, Valentin M., Yang, Zhiyong, Kim, Jessica, Buehler, Eugen, Patel, Amit, Martin, Scott E., Zhang, Ping-Wu, Ge, Yan, Duan, Yukan, Fuller, John, Kim, Byung-Jin, Hamed, Eman, Chamling, Xitiz, Lei, Lei, Fraser, Iain D.C., Ronai, Ze’ev A., Berlinicke, Cynthia A., Zack, Donald J.

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ATF2 - at the crossroad of nuclear and cytosolic functions von Lau, Eric, Ronai, Ze'ev A

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Melanoma models for the next generation of therapies von Patton, E. Elizabeth, Mueller, Kristen L., Adams, David J., Anandasabapathy, Niroshana, Aplin, Andrew E., Bertolotto, Corine, Bosenberg, Marcus, Ceol, Craig J., Burd, Christin E., Chi, Ping, Herlyn, Meenhard, Holmen, Sheri L., Karreth, Florian A., Kaufman, Charles K., Khan, Shaheen, Kobold, Sebastian, Leucci, Eleonora, Levy, Carmit, Lombard, David B., Lund, Amanda W., Marie, Kerrie L., Marine, Jean-Christophe, Marais, Richard, McMahon, Martin, Robles-Espinoza, Carla Daniela, Ronai, Ze'ev A., Samuels, Yardena, Soengas, Maria S., Villanueva, Jessie, Weeraratna, Ashani T., White, Richard M., Yeh, Iwei, Zhu, Jiyue, Zon, Leonard I., Hurlbert, Marc S., Merlino, Glenn

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The gut microbiome: an unexpected player in cancer immunity von Peterson, Scott N, Bradley, Linda M, Ronai, Ze’ev A

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UPR, autophagy, and mitochondria crosstalk underlies the ER stress response von Senft, Daniela, Ronai, Ze’ev A.

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Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors von Qi, Jianfei, Nakayama, Koh, Cardiff, Robert D., Borowsky, Alexander D., Kaul, Karen, Williams, Roy, Krajewski, Stan, Mercola, Dan, Carpenter, Philip M., Bowtell, David, Ronai, Ze'ev A.

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PKCε Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria von Lau, Eric, Kluger, Harriet, Varsano, Tal, Lee, KiYoung, Scheffler, Immo, Rimm, David L., Ideker, Trey, Ronai, Ze'ev A.

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Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival von Pathria, Gaurav, Scott, David A, Feng, Yongmei, Sang Lee, Joo, Fujita, Yu, Zhang, Gao, Sahu, Avinash D, Ruppin, Eytan, Herlyn, Meenhard, Osterman, Andrei L, Ronai, Ze'ev A

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ATF2, a paradigm of the multifaceted regulation of transcription factors in biology and disease von Watson, Gregory, Ronai, Ze’ev A., Lau, Eric

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Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax von Herzog, Lee-or, Walters, Beth, Buono, Roberta, Lee, J. Scott, Mallya, Sharmila, Fung, Amos, Chiu, Honyin, Nguyen, Nancy, Li, Boyang, Pinkerton, Anthony B., Jackson, Michael R., Schneider, Robert J., Ronai, Ze’ev A., Fruman, David A.

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ATF2: A transcription factor that elicits oncogenic or tumor suppressor activities von Bhoumik, Anindita, Ronai, Ze'ev

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Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice von Li, Yan, Tinoco, Roberto, Elmén, Lisa, Segota, Igor, Xian, Yibo, Fujita, Yu, Sahu, Avinash, Zarecki, Raphy, Marie, Kerrie, Feng, Yongmei, Khateb, Ali, Frederick, Dennie T., Ashkenazi, Shiri K., Kim, Hyungsoo, Perez, Eva Guijarro, Day, Chi-Ping, Segura Muñoz, Rafael S., Schmaltz, Robert, Yooseph, Shibu, Tam, Miguel A., Zhang, Tongwu, Avitan-Hersh, Emily, Tzur, Lihi, Roizman, Shoshana, Boyango, Ilanit, Bar-Sela, Gil, Orian, Amir, Kaufman, Randal J., Bosenberg, Marcus, Goding, Colin R., Baaten, Bas, Levesque, Mitchell P., Dummer, Reinhard, Brown, Kevin, Merlino, Glenn, Ruppin, Eytan, Flaherty, Keith, Ramer-Tait, Amanda, Long, Tao, Peterson, Scott N., Bradley, Linda M., Ronai, Ze’ev A.

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SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation von Jiang, Tian-Xia, Zou, Jiang-Bo, Zhu, Qian-Qian, Liu, Cui Hua, Wang, Guang-Fei, Du, Ting-Ting, Luo, Zi-Yu, Guo, Fang, Zhou, Lu-Ming, Liu, Juan-Juan, Zhang, Wensheng, Shu, You-Sheng, Yu, Li, Li, Peng, Ronai, Ze’ev A., Matsuzawa, Shu-ichi, Goldberg, Alfred L., Qiu, Xiao-Bo

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Translational Homeostasis via the mRNA Cap-Binding Protein, eIF4E von Yanagiya, Akiko, Suyama, Eigo, Adachi, Hironori, Svitkin, Yuri V., Aza-Blanc, Pedro, Imataka, Hiroaki, Mikami, Satoshi, Martineau, Yvan, Ronai, Ze'ev A., Sonenberg, Nahum

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The Ubiquitin Ligase Siah2 and the Hypoxia Response von Nakayama, Koh, Qi, Jianfei, Ronai, Ze'ev

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SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth von Lazar, Ikrame, Fabre, Bertrand, Feng, Yongmei, Khateb, Ali, Turko, Patrick, Martinez Gomez, Julia M, Frederick, Dennie T, Levesque, Mitchell P, Feld, Lea, Zhang, Gao, Zhang, Tongwu, James, Brian, Shklover, Jeny, Avitan-Hersh, Emily, Livneh, Ido, Scortegagna, Marzia, Brown, Kevin, Larsson, Ola, Topisirovic, Ivan, Wolfenson, Haguy, Herlyn, Meenhard, Flaherty, Keith, Dummer, Reinhard, Ronai, Ze'ev A

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