Synthesis of Deuterated Endochin‐Like Quinolones von Pou, Sovitj, Winter, Rolf W., Liebman, Katherine M., Dodean, Rosie A., Nilsen, Aaron, DeBarber, Andrea, Doggett, J. Stone, Riscoe, Michael K.

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Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo von Pal, Anasuya C, Renard, Isaline, Singh, Pallavi, Vydyam, Pratap, Chiu, Joy E, Pou, Sovitj, Winter, Rolf W, Dodean, Rozalia, Frueh, Lisa, Nilsen, Aaron C, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri

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Discovery, Synthesis, and Optimization of Antimalarial 4(1H)‑Quinolone-3-Diarylethers von Nilsen, Aaron, Miley, Galen P, Forquer, Isaac P, Mather, Michael W, Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M, Stickles, Allison M, Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L, Hinrichs, David J, Winter, Rolf W, Charman, Susan A, Zakharov, Lev N, Bathurst, Ian, Burrows, Jeremy N, Vaidya, Akhil B, Riscoe, Michael K

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Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone von Lawres, Lauren A, Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P, Renard, Isaline, Virji, Azan Z, Boulard, Pierre, Rodriguez, Eduardo X, Allen, Alexander J, Pou, Sovitj, Wegmann, Keith W, Winter, Rolf W, Nilsen, Aaron, Mao, Jialing, Preston, Douglas A, Belperron, Alexia A, Bockenstedt, Linda K, Hinrichs, David J, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri

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Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil von van Schalkwyk, Donelly A, Riscoe, Michael K, Pou, Sovitj, Winter, Rolf W, Nilsen, Aaron, Duffey, Maëlle, Moon, Robert W, Sutherland, Colin J

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Synthesis of Pentafluorosulfanylpyrazole and Pentafluorosulfanyl-1,2,3-triazole and Their Derivatives as Energetic Materials by Click Chemistry von Ye, Chengfeng, Gard, Gary L, Winter, Rolf W, Syvret, Robert G, Twamley, Brendan, Shreeve, Jean'ne M

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Long-acting intramuscular injections of ELQ-331, an antimalarial agent von Karunakaran, Dipu, Mutyam, Shravan K., Fu, Melody, Chen, Jiaming, Pham, Kim Hue Nicky, Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Dodean, Rozalia A., Smilkstein, Martin J., Riscoe, Michael K., Shankar, Gita

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Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria von Stickles, Allison M, Smilkstein, Martin J, Morrisey, Joanne M, Li, Yuexin, Forquer, Isaac P, Kelly, Jane X, Pou, Sovitj, Winter, Rolf W, Nilsen, Aaron, Vaidya, Akhil B, Riscoe, Michael K

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Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparum von Stickles, Allison M, de Almeida, Mariana Justino, Morrisey, Joanne M, Sheridan, Kayla A, Forquer, Isaac P, Nilsen, Aaron, Winter, Rolf W, Burrows, Jeremy N, Fidock, David A, Vaidya, Akhil B, Riscoe, Michael K

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New Scalable Synthetic Routes to ELQ-300, ELQ-316, and Other Antiparasitic Quinolones von Pou, Sovitj, Dodean, Rozalia A, Frueh, Lisa, Liebman, Katherine M, Gallagher, Rory T, Jin, Haihong, Jacobs, Robert T, Nilsen, Aaron, Stuart, David R, Doggett, J. Stone, Riscoe, Michael K, Winter, Rolf W

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Effective Therapy Targeting Cytochrome bc 1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection von Chiu, Joy E, Renard, Isaline, Pal, Anasuya C, Singh, Pallavi, Vydyam, Pratap, Thekkiniath, Jose, Kumar, Madelyn, Gihaz, Shalev, Pou, Sovitj, Winter, Rolf W, Dodean, Rozalia, Frueh, Lisa, Nilsen, Aaron C, Riscoe, Michael K, Doggett, J Stone, Mamoun, Choukri Ben

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Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection von Chiu, Joy E, Renard, Isaline, Pal, Anasuya C, Singh, Pallavi, Vydyam, Pratap, Thekkiniath, Jose, Kumar, Madelyn, Gihaz, Shalev, Pou, Sovitj, Winter, Rolf W, Dodean, Rozalia, Frueh, Lisa, Nilsen, Aaron C, Riscoe, Michael K, Doggett, J. Stone, Mamoun, Choukri Ben

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria von Smilkstein, Martin J, Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A, Dodean, Rozalia A, Frueh, Lisa, Hinrichs, David J, Li, Yuexin, Martinson, Thomas, Munar, Myrna Y, Winter, Rolf W, Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R, Kelly, Jane X, Kappe, Stefan H I, Wilder, Brandon K, Riscoe, Michael K

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Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy von Stickles, Allison M, Ting, Li-Min, Morrisey, Joanne M, Li, Yuexin, Mather, Michael W, Meermeier, Erin, Pershing, April M, Forquer, Isaac P, Miley, Galen P, Pou, Sovitj, Winter, Rolf W, Hinrichs, David J, Kelly, Jane X, Kim, Kami, Vaidya, Akhil B, Riscoe, Michael K, Nilsen, Aaron

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Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis von Vydyam, Pratap, Chand, Meenal, Pou, Sovitj, Winter, Rolf W., Liebman, Katherine M., Nilsen, Aaron, Doggett, J. Stone, Riscoe, Michael K., Ben Mamoun, Choukri

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Discovery of dual function acridones as a new antimalarial chemotype von Hinrichs, David J, Wittlin, Sergio, Cooper, Roland A, Riscoe, Michael K, Dodean, Rozalia A, Kelly, Jane X, Winter, Rolf, Smilkstein, Martin J, Janowsky, Aaron, Lane, Kristin D, Johnson, Robert A, Brun, Reto

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A New Scalable Synthesis of ELQ-300, ELQ-316, and other Antiparasitic Quinolones von Pou, Sovitj, Dodean, Rozalia A, Frueh, Lisa, Liebman, Katherine M, Gallagher, Rory T, Jin, Haihong, Jacobs, Robert T, Nilsen, Aaron, Stuart, David R, Doggett, J Stone, Riscoe, Michael K, Winter, Rolf W

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Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi von Silva, Marta G, Bastos, Reginaldo G, Stone Doggett, J, Riscoe, Michael K, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A, Nilsen, Aaron, Suarez, Carlos E

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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials von Dodean, Rozalia A, Kancharla, Papireddy, Li, Yuexin, Melendez, Victor, Read, Lisa, Bane, Charles E, Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J, Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E, Nolan, Christina, Huezo, Stephanie J, Rasmussen, Stephanie A, Stephens, Melissa T, Tan, John C, Cooper, Roland A, Smilkstein, Martin J, Pou, Sovitj, Winter, Rolf W, Riscoe, Michael K, Kelly, Jane X

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Sontochin as a Guide to the Development of Drugs against Chloroquine-Resistant Malaria von POU, Sovitj, WINTER, Rolf W, NILSEN, Aaron, XU KELLY, Jane, YUEXIN LI, STONE DOGGETT, J, RISCOE, Erin W, WEGMANN, Keith W, HINRICHS, David J, RISCOE, Michael K

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