Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure von Follmann, Markus, Ackerstaff, Jens, Redlich, Gorden, Wunder, Frank, Lang, Dieter, Kern, Armin, Fey, Peter, Griebenow, Nils, Kroh, Walter, Becker-Pelster, Eva-Maria, Kretschmer, Axel, Geiss, Volker, Li, Volkhart, Straub, Alexander, Mittendorf, Joachim, Jautelat, Rolf, Schirok, Hartmut, Schlemmer, Karl-Heinz, Lustig, Klemens, Gerisch, Michael, Knorr, Andreas, Tinel, Hanna, Mondritzki, Thomas, Trübel, Hubert, Sandner, Peter, Stasch, Johannes-Peter

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Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors von Sommer, Anette, Kopitz, Charlotte, Schatz, Christoph A, Nising, Carl F, Mahlert, Christoph, Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Hammer, Stefanie, Greven, Simone, Schuhmacher, Joachim, Braun, Manuela, Zierz, Ruprecht, Wittemer-Rump, Sabine, Harrenga, Axel, Dittmer, Frank, Reetz, Frank, Apeler, Heiner, Jautelat, Rolf, Huynh, Hung, Ziegelbauer, Karl, Kreft, Bertolt

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Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase von Schulze, Volker K, Klar, Ulrich, Kosemund, Dirk, Wengner, Antje M, Siemeister, Gerhard, Stöckigt, Detlef, Neuhaus, Roland, Lienau, Philip, Bader, Benjamin, Prechtl, Stefan, Holton, Simon J, Briem, Hans, Marquardt, Tobias, Schirok, Hartmut, Jautelat, Rolf, Bohlmann, Rolf, Nguyen, Duy, Fernández-Montalván, Amaury E, Bömer, Ulf, Eberspaecher, Uwe, Brüning, Michael, Döhr, Olaf, Raschke, Marian, Kreft, Bertolt, Mumberg, Dominik, Ziegelbauer, Karl, Brands, Michael, von Nussbaum, Franz, Koppitz, Marcus

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Studies towards Trichodimerol: Novel Cascade Reactions and Polycyclic Frameworks von Nicolaou, K. C., Jautelat, Rolf, Vassilikogiannakis, Georgios, Baran, Phil S., Simonsen, Klaus B.

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New Generation of sGC Stimulators: Discovery of Imidazo[1,2‑a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Re... von Vakalopoulos, Alexandros, Wunder, Frank, Hartung, Ingo V., Redlich, Gorden, Jautelat, Rolf, Buchgraber, Philipp, Hassfeld, Jorma, Gromov, Alexey V., Lindner, Niels, Bierer, Donald, Gries, Jörg, Kroh, Walter, Paulsen, Holger, Mittendorf, Joachim, Lang, Dieter, Becker-Pelster, Eva, Brockschnieder, Damian, Geiss, Volker, Li, Volkhart, Straub, Alexander, Knorr, Andreas, Mondritzki, Thomas, Trübel, Hubert, Raschke, Marian, Schaefer, Martina, Thomas, Dirk, Sandner, Peter, Stasch, Johannes-Peter, Follmann, Markus

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Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor von Collin, Marie‐Pierre, Lobell, Mario, Hübsch, Walter, Brohm, Dirk, Schirok, Hartmut, Jautelat, Rolf, Lustig, Klemens, Bömer, Ulf, Vöhringer, Verena, Héroult, Mélanie, Grünewald, Sylvia, Hess‐Stumpp, Holger

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Abstract 46: Preclinical activity of novel antibody-drug conjugates with pyrrole-based kinesin spindle protein inhibitors targeting different tumor antigens von Sommer, Anette, Berndt, Sandra, Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Wittrock, Sven, Rebstock, Anne-Sophie, Dietz, Lisa, Mahlert, Christoph, Greven, Simone, Griebenow, Nils, Cancho-Grande, Yolanda, Jautelat, Rolf, Apeler, Heiner, Kreft, Bertolt

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Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class von Lerchen, Hans-Georg, Wittrock, Sven, Griebenow, Nils, Lobell, Mario, Rebstock, Anne-Sophie, Cancho-Grande, Yolanda, Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Sommer, Anette, Berndt, Sandra, Terjung, Carsten, Apeler, Heiner, Kreft, Bertolt, Jautelat, Rolf

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Abstract 4491: FGFR2-ADC potently and selectively inhibits growth of gastric and breast cancer xenograft models von Sommer, Anette, Nising, Carl F., Mahlert, Christoph, Kopitz, Charlotte C., Lerchen, Hans-Georg, Greven, Simone, Stelte-Ludwig, Beatrix, Schuhmacher, Joachim, Zierz, Ruprecht, Wittemer-Rump, Sabine, Schatz, Christoph, Reetz, Frank, Apeler, Heiner, Jautelat, Rolf, Kreft, Bertolt, Ziegelbauer, Karl

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From the Insoluble Dye Indirubin towards Highly Active, Soluble CDK2-Inhibitors von Jautelat, Rolf, Brumby, Thomas, Schäfer, Martina, Briem, Hans, Eisenbrand, Gerhard, Schwahn, Stefan, Krüger, Martin, Lücking, Ulrich, Prien, Olaf, Siemeister, Gerhard

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Macrocyclic Aminopyrimidines as Multitarget CDK and VEGF-R Inhibitors with Potent Antiproliferative Activities von Lücking, Ulrich, Siemeister, Gerhard, Schäfer, Martina, Briem, Hans, Krüger, Martin, Lienau, Philip, Jautelat, Rolf

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Kinase Data Mining: Dealing with the Information (Over-)Flow von Eis, Knut, Ince, Stuart J, Jahn, Carsten, Jautelat, Rolf, Katchourovsky, Vladimir, Kettschau, Georg, Woloszczak, Rolf

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A Novel Oxidative Cleavage of the Steroidal Skeleton von Jautelat, Rolf, Müller-Fahrnow, Anke, Winterfeldt, Ekkehard

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A Novel Route to the Fused Maleic Anhydride Moiety of CP Molecules von Nicolaou, K. C., Baran, Phil S., Jautelat, Rolf, He, Yun, Fong, Kin Chiu, Choi, Ha-Soon, Yoon, Won Hyung, Zhong, Yong-Li

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17alpha-alkyl-17beta-oxy-estratrienes, uses thereof and pharmaceutical preparations von BOHLMANN ROLF,JAUTELAT ROLF,PETROV ORLIN,HOFFMANNJENS,HEINRICH NIKOLAUS,KROLL JORG,REICHEL ANDREAS,LICHTNER ROSEMARIE

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SUBSTITUTED IMIDAZOPYRIDAZINES von KLAR, ULRICH, LIENAU, PHILIP, KOPPITZ, MARCUS, BOHLMANN, ROLF, SIEMEISTER, GERHARD, KOSEMUND, DIRK, WENGNER, ANTJE, MARGRET, JAUTELAT, ROLF

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Substituted 5-fluoro-1H-pyrazolopyridines and their use von Wunder, Frank, Redlich, Gorden, Hartmann, Elke, Mittendorf, Joachim, Schlemmer, Karl-Heinz, Becker, Eva-Maria, Bierer, Donald, Griebenow, Nils, Jautelat, Rolf, Follmann, Markus, Kroh, Walter, Li, Volkhart Min-Jian, Stasch, Johannes-Peter, Knorr, Andreas, Ackerstaff, Jens

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Directed Synthesis of Nonsymmetrical Bis-Steroidal Pyrazines and the First Biologically Active Cephalostatin Analogues von Drögemüller, Michael, Jautelat, Rolf, Winterfeldt, Ekkehard

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SULFOXIMINE-SUBSTITUTED ANILINO-PYRIMIDINE DERIVATIVES AS CDK INHIBITORS, PRODUCTION AND USE THEREOF AS MEDICINAL PRODUCTS von LIENAU, PHILIP, LUECKING, ULRICH, SIEMEISTER, GERHARD, SCHULZE, JULIA, JAUTELAT, ROLF

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SULPHONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THEIR PREPARATION AND USE AS MEDICAMENTS von LIENAU, PHILIP, LUECKING, ULRICH, SIEMEISTER, GERHARD, SCHULZE, JULIA, JAUTELAT, ROLF

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