Development of ADS051, an oral, gut‐restricted, small molecule neutrophil modulator for the treatment of neutrophil‐mediated inflammatory diseases von Murphy, Christopher K., Dixit, Bharat, Oleson, Frederick B., Dolle, Roland E., Farquhar, Ronald, McCormick, Beth A.

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The Discovery and Development of the N-Substituted trans-3,4-Dimethyl-4-(3′-hydroxyphenyl)piperidine Class of Pure Opioid Receptor Antagonists von Carroll, F. Ivy, Dolle, Roland E.

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A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases von Docherty, Callum Ah, Fernando, Anuruddika J, Rosli, Sarah, Lam, Maggie, Dolle, Roland E, Navia, Manuel A, Farquhar, Ronald, La France, Danny, Tate, Michelle D, Murphy, Christopher K, Rossi, Adriano G, Mansell, Ashley

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Mu Opioid Receptor Antagonists: Recent Developments von Goodman, Allan J., Le Bourdonnec, Bertrand, Dolle, Roland E.

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10-Hydroxy-10,9-boroxarophenanthrenes:  Versatile Synthetic Intermediates to 3,4-Benzocoumarins and Triaryls von Zhou, Q. Jean, Worm, Karin, Dolle, Roland E

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Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington's disease neurodegeneration von Lee, Seong Won, Oh, Young Mi, Victor, Matheus B, Yang, Yan, Chen, Shawei, Strunilin, Ilya, Dahiya, Sonika, Dolle, Roland E, Pak, Stephen C, Silverman, Gary A, Perlmutter, David H, Yoo, Andrew S

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Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors von Zhang, Jing, Yang, Qingyi, Cross, Jason B, Romero, Jan Antoinette C, Poutsiaka, Katherine M, Epie, Felix, Bevan, Douglas, Wang, Bin, Zhang, Yanzhi, Chavan, Ajit, Zhang, Xin, Moy, Terence, Daniel, Anu, Nguyen, Kien, Chamberlain, Brian, Carter, Nicole, Shotwell, Joseph, Silverman, Jared, Metcalf, Chester A, Ryan, Dominic, Lippa, Blaise, Dolle, Roland E

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Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design von Cross, Jason B, Zhang, Jing, Yang, Qingyi, Mesleh, Michael F, Romero, Jan Antoinette C, Wang, Bin, Bevan, Doug, Poutsiaka, Katherine M, Epie, Felix, Moy, Terence, Daniel, Anu, Shotwell, Joseph, Chamberlain, Brian, Carter, Nicole, Andersen, Ole, Barker, John, Ryan, M. Dominic, Metcalf, Chester A, Silverman, Jared, Nguyen, Kien, Lippa, Blaise, Dolle, Roland E

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Historical Overview of Chemical Library Design von Dolle, Roland E.

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Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors von Zhang, Jing, Yang, Qingyi, Romero, Jan Antoinette C, Cross, Jason, Wang, Bin, Poutsiaka, Katherine M, Epie, Felix, Bevan, Douglas, Wu, Yuchuan, Moy, Terence, Daniel, Anu, Chamberlain, Brian, Carter, Nicole, Shotwell, Joseph, Arya, Anu, Kumar, Vipul, Silverman, Jared, Nguyen, Kien, Metcalf, Chester A, Ryan, Dominic, Lippa, Blaise, Dolle, Roland E

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High-performance liquid chromatographic enantioseparation of methanobenzazocines von Barker, William M., Worm, Karin, Dolle, Roland E.

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Solid/Solution-Phase Annulation Reagents: Single-Step Synthesis of Cyclic Amine Derivatives von Dolle, Roland E., MacLeod, Calum, Martinez-Teipel, Blanca, Barker, William, Seida, Pamela R., Herbertz, Torsten

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Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondria! Diseases von Dang, Xiawei, Zhang, Lihong, Franco, Antonietta, Li, Jiajia, Rocha, Agostinho G., Devanathan, Sriram, Dolle, Roland E., Bernstein, Peter R., Dorn, Gerald W.

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Synthesis and Pharmacological Evaluation of Novel Octahydro-1H-pyrido[1,2-a]pyrazine as μ-Opioid Receptor Antagonists von Le Bourdonnec, Bertrand, Goodman, Allan J, Graczyk, Thomas M, Belanger, Serge, Seida, Pamela R, DeHaven, Robert N, Dolle, Roland E

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Novel malonamide derivatives as potent κ opioid receptor agonists von Chu, Guo-Hua, Gu, Minghua, Cassel, Joel A., Belanger, Serge, Graczyk, Thomas M., DeHaven, Robert N., Conway-James, Nathalie, Koblish, Michael, Little, Patrick J., DeHaven-Hudkins, Diane L., Dolle, Roland E.

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Biaryl cannabinoid mimetics—Synthesis and structure–activity relationship von Worm, Karin, Zhou, Q. Jean, Stabley, Gabriel J., DeHaven, Robert N., Dolle, Roland E.

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Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists von WORM, Karin, WEAVER, Damian G, KOBLISH, Michael, BROGDON, Bernice L, SMITH, Steven A, DOLLE, Roland E, GREEN, Rosalyn C, SAEUI, Christopher T, DULAY, Doreen-Marie S, BARKER, William M, CASSEL, Joel A, STABLEY, Gabriel J, DEHAVEN, Robert N, LABUDA, Christopher J

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Discovery of a series of aminopiperidines as novel iNOS inhibitors von Bourdonnec, Bertrand Le, Leister, Lara K., Ajello, Christopher A., Cassel, Joel A., Seida, Pamela R., O’Hare, Heather, Gu, Minghua, Chu, Guo-Hua, Tuthill, Paul A., DeHaven, Robert N., Dolle, Roland E.

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Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997 von Dolle, R E

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Further studies of tyrosine surrogates in opioid receptor peptide ligands von Dolle, Roland E., Michaut, Mathieu, Martinez-Teipel, Blanca, Belanger, Serge, Graczyk, Thomas M., DeHaven, Robert N.

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