Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry von Rohrer, Susan P., Birzin, Elizabeth T., Mosley, Ralph T., Berk, Scott C., Hutchins, Steven M., Shen, Dong-Ming, Xiong, Yusheng, Hayes, Edward C., Parmar, Rupa M., Foor, Forrest, Mitra, Sudha W., Degrado, Sylvia J., Shu, Min, Klopp, John M., Cai, Sheng-Jian, Blake, Allan, Wanda W. S. Chan, Pasternak, Alex, Yang, Lihu, Patchett, Arthur A., Smith, Roy G., Chapman, Kevin T., Schaeffer, James M.

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The discovery of tetrahydrofluorenones as a new class of estrogen receptor β-subtype selective ligands von Wilkening, R.R., Ratcliffe, R.W., Tynebor, E.C., Wildonger, K.J., Fried, A.K., Hammond, M.L., Mosley, R.T., Fitzgerald, P.M.D., Sharma, N., McKeever, B.M., Nilsson, S., Carlquist, M., Thorsell, A., Locco, L., Katz, R., Frisch, K., Birzin, E.T., Wilkinson, H.A., Mitra, S., Cai, S., Hayes, E.C., Schaeffer, J.M., Rohrer, S.P.

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Estrogen receptor β-subtype selective tetrahydrofluorenones: Use of a fused pyrazole as a phenol bioisostere von Wilkening, R.R., Ratcliffe, R.W., Fried, A.K., Meng, D., Sun, W., Colwell, L., Lambert, S., Greenlee, M., Nilsson, S., Thorsell, A., Mojena, M., Tudela, C., Frisch, K., Chan, W., Birzin, E.T., Rohrer, S.P., Hammond, M.L.

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Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7 von Peekhaus, NT, Chang, T, Hayes, EC, Wilkinson, HA, Mitra, SW, Schaeffer, JM, Rohrer, SP

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Identification of somatostatin receptors controlling growth hormone and thyrotropin secretion in the chicken using receptor subtype-specific agonists von Geris, KL, de Groef, B, Rohrer, SP, Geelissen, S, Kuhn, ER, Darras, VM

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Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice von Viollet, C., Vaillend, C., Videau, C., Bluet-Pajot, M. T., Ungerer, A., L'héritier, A., Kopp, C., Potier, B., Billard, J. -M., Schaeffer, J., Smith, R. G., Rohrer, S. P., Wilkinson, H., Zheng, H., Epelbaum, J.

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Selective estrogen receptor-beta (SERM-beta) compounds modulate raphe nuclei tryptophan hydroxylase-1 (TPH-1) mRNA expression and cause antidepressant-like effects in the forced sw... von Clark, J.A., Alves, S., Gundlah, C., Rocha, B., Birzin, E.T., Cai, S.-J., Flick, R., Hayes, E., Ho, K., Warrier, S., Pai, L., Yudkovitz, J., Fleischer, R., Colwell, L., Li, S., Wilkinson, H., Schaeffer, J., Wilkening, R., Mattingly, E., Hammond, M., Rohrer, S.P.

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Nonpeptidyl Somatostatin Agonists Demonstrate That sst2 and sst5 Inhibit Stimulated Growth Hormone Secretion from Rat Anterior Pituitary Cells von Parmar, R.M., Chan, W.W.-S., Dashkevicz, M., Hayes, E.C., Rohrer, S.P., Smith, R.G., Schaeffer, J.M., Blake, A.D.

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Synthesis of a Substance P Antagonist with a Somatostatin Scaffold:  Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry von Liu, Josephine, Underwood, Dennis J, Cascieri, Margaret A, Rohrer, Susan P, Cantin, Louis-David, Chicchi, Gary, Smith, Amos B, Hirschmann, Ralph

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Organization of minicircle genes for guide RNAs in trypanosoma brucei von Pollard, Victoria W., Rohrer, Susan P., Michelotti, Emil F., Hancock, Kathy, Hajduk, Stephen L.

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Ivermectin binding sites in sensitive and resistant Haemonchus contortus von Rohrer, S.P, Birzin, E.T, Eary, C.H, Schaeffer, J.M, Shoops, W.L

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Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues von ZHIXIONG YE, YINGDUO GAO, LOCCO, L, PARMAR, R. M, CHAN, W. W.-S, SCHAEFFER, J. M, SMITH, R. G, PATCHETT, A. A, NARGUND, R. P, BAKSHI, R. K, CHEN, M.-H, ROHRER, S. P, FEIGHNER, S. D, PONG, S.-S, HOWARD, A. D, BLAKE, A, BIRZIN, E. T

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Photoaffinity Labeling of Avermectin Binding Sites from Caenorhabditis elegans and Drosophila melanogaster von Rohrer, Susan P., Meinke, Peter T., Hayes, Edward C., Mrozik, Helmut, Schaeffer, James M.

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Potent, orally bioavailable somatostatin agonists: Good absorption achieved by urea backbone cyclization von Pasternak, Alexander, Pan, Yanping, Marino, Dominick, Sanderson, Philip E., Mosley, Ralph, Rohrer, Susan P., Birzin, Elizabeth T., Huskey, Su-Er Wu, Jacks, Tom, Schleim, Klaus D, Cheng, Kang, Schaeffer, James M., Patchett, Arthur A., Yang, Lihu

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Avermectins and milbemycins against Fasciola hepatica: In vivo drug efficacy and in Vitro receptor binding von Shoop, W.L., Ostlind, D.A., Rohrer, S.P., Mickle, G., Haines, H.W., Michael, B.F., Mrozik, H., Fisher, M.H.

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Synthesis and Biological Activities of Potent Peptidomimetics Selective for Somatostatin Receptor Subtype 2 von Yang, Lihu, Berk, Scott C., Rohrer, Susan P., Mosley, Ralph T., Guo, Liangqin, Underwood, Dennis J., Arison, Byron H., Birzin, Elizabeth T., Hayes, Edward C., Mitra, Sudha W., Parmar, Rupa M., Cheng, Kang, Wu, Tsuei-Ju, Butler, Bridgette S., Foor, Forrest, Pasternak, Alexander, Pan, Yanping, Silva, Maria, Freidinger, Roger M., Smith, Roy G., Chapman, Kevin, Schaeffer, James M., Patchett, Arthur A.

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Immunoaffinity purification of avermectin-binding proteins from the free-living nematode Caenorhabditis elegans and the fruitfly Drosophila melanogaster von Rohrer, S.P, Jacobson, E.B, Hayes, E.C, Birzin, E.T, Schaeffer, J.M

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Purification and characterization of phosphoenolpyruvate carboxykinase from the parasitic helminth Ascaris suum von Rohrer, S P, Saz, H J, Nowak, T

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A Potent, Nonpeptidyl 1H-Quinolone Antagonist for the Gonadotropin-Releasing Hormone Receptor von DeVita, Robert J, Walsh, Thomas F, Young, Jonathan R, Jiang, Jinlong, Ujjainwalla, Feroze, Toupence, Richard B, Parikh, Mamta, Huang, Song X, Fair, Jason A, Goulet, Mark T, Wyvratt, Matthew J, Lo, Jane-L, Ren, Ning, Yudkovitz, Joel B, Yang, Yi T, Cheng, Kang, Cui, Jisong, Mount, George, Rohrer, Susan P, Schaeffer, James M, Rhodes, Linda, Drisko, Jennifer E, McGowan, Erin, MacIntyre, D. Euan, Vincent, Styliani, Carlin, Josephine R, Cameron, Judith, Smith, Roy G

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Identification and characterization of subtype selective somatostatin receptor agonists von Rohrer, Susan P., Schaeffer, James M.

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