Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme von Hamilton, Matthew M, Mseeh, Faika, McAfoos, Timothy J, Leonard, Paul G, Reyna, Naphtali J, Harris, Angela L, Xu, Alan, Han, Michelle, Soth, Michael J, Czako, Barbara, Theroff, Jay P, Mandal, Pijus K, Burke, Jason P, Virgin-Downey, Brett, Petrocchi, Alessia, Pfaffinger, Dana, Rogers, Norma E, Parker, Connor A, Yu, Simon S, Jiang, Yongying, Krapp, Stephan, Lammens, Alfred, Trevitt, Graham, Tremblay, Martin R, Mikule, Keith, Wilcoxen, Keith, Cross, Jason B, Jones, Philip, Marszalek, Joseph R, Lewis, Richard T

Volltext

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation von Sun, Yuting, Bandi, Madhavi, Lofton, Timothy, Smith, Melinda, Bristow, Christopher A., Carugo, Alessandro, Rogers, Norma, Leonard, Paul, Chang, Qing, Mullinax, Robert, Han, Jing, Shi, Xi, Seth, Sahil, Meyers, Brooke A., Miller, Meredith, Miao, Lili, Ma, Xiaoyan, Feng, Ningping, Giuliani, Virginia, Geck Do, Mary, Czako, Barbara, Palmer, Wylie S., Mseeh, Faika, Asara, John M., Jiang, Yongying, Morlacchi, Pietro, Zhao, Shuping, Peoples, Michael, Tieu, Trang N., Warmoes, Marc O., Lorenzi, Philip L., Muller, Florian L., DePinho, Ronald A., Draetta, Giulio F., Toniatti, Carlo, Jones, Philip, Heffernan, Timothy P., Marszalek, Joseph R.

Volltext

Enhancement of therapeutic protein in vivo activities through glycoengineering von Elliott, Steve, Lorenzini, Tony, Asher, Sheilah, Aoki, Ken, Brankow, David, Buck, Lynette, Busse, Leigh, Chang, David, Fuller, Janis, Grant, James, Hernday, Natasha, Hokum, Martha, Hu, Sylvia, Knudten, Andrew, Levin, Nancy, Komorowski, Renee, Martin, Frank, Navarro, Rachell, Osslund, Timothy, Rogers, Gary, Rogers, Norma, Trail, Geri, Egrie, Joan

Volltext

Control of rHuEPO biological activity: The role of carbohydrate von Elliott, Steve, Egrie, Joan, Browne, Jeff, Lorenzini, Tony, Busse, Leigh, Rogers, Norma, Ponting, Ian

Volltext

Oxidation of Nitric Oxide in Aqueous Solution to Nitrite but not Nitrate: Comparison with Enzymatically Formed Nitric Oxide From L-Arginine von Ignarro, Louis J., Fukuto, Jon M., Griscavage, Jeannete M., Rogers, Norma E., Byrns, Russell E.

Volltext

Seed saving in Atlantic Canada: Sustainable food through sharing and education von Worden-Rogers, Norma Jean, Glasgow, Kathleen, Knezevic, Irena, Hughes, Stephanie

Volltext

Negative Feedback Regulation of Endothelial Cell Function by Nitric Oxide von Buga, Georgette M, Griscavage, Jeanette M, Rogers, Norma E, Ignarro, Louis J

Volltext

Cutting Edge: Antisense Knockdown of Inducible Nitric Oxide Synthase Inhibits Induction of Experimental Autoimmune Encephalomyelitis in SJL/J Mice von Ding, Minzhen, Zhang, Ming, Wong, Joyce L, Rogers, Norma E, Ignarro, Louis J, Voskuhl, Rhonda R

Volltext

Discovery of IPN60090, a Clinical Stage Selective Glutaminase‑1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties von Soth, Michael J, Le, Kang, Di Francesco, Maria Emilia, Hamilton, Matthew M, Liu, Gang, Burke, Jason P, Carroll, Chris L, Kovacs, Jeffrey J, Bardenhagen, Jennifer P, Bristow, Christopher A, Cardozo, Mario, Czako, Barbara, de Stanchina, Elisa, Feng, Ningping, Garvey, Jill R, Gay, Jason P, Do, Mary K. Geck, Greer, Jennifer, Han, Michelle, Harris, Angela, Herrera, Zachary, Huang, Sha, Giuliani, Virginia, Jiang, Yongying, Johnson, Sarah B, Johnson, Troy A, Kang, Zhijun, Leonard, Paul G, Liu, Zhen, McAfoos, Timothy, Miller, Meredith, Morlacchi, Pietro, Mullinax, Robert A, Palmer, Wylie S, Pang, Jihai, Rogers, Norma, Rudin, Charles M, Shepard, Hannah E, Spencer, Nakia D, Theroff, Jay, Wu, Qi, Xu, Alan, Yau, Ju Anne, Draetta, Giulio, Toniatti, Carlo, Heffernan, Timothy P, Jones, Philip

Volltext

Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible f... von Kiriakidis, Serafim, Hoer, Simon S., Burrows, Natalie, Biddlecome, Gloria, Khan, Moddasar N., Thinnes, Cyrille C., Schofield, Christopher J., Rogers, Norma, Botto, Marina, Paleolog, Ewa, Maxwell, Patrick H.

Volltext

Abstract 3277: IACS-9779, a development candidate that inhibits 2,3-dioxygenase (IDO) activity by blocking heme incorporation into IDO apoenzyme von Mseeh, Faika, Hamilton, Matthew M., Marszalek, Joseph R., Rogers, Norma E., Parker, Connor A., Yu, Simon S., Liu, Zhen, Reyna, Naphtali J., McAfoos, Timothy, Virgin-Downey, Brett W., Leonard, Paul G., Cross, Jason B., Feng, Ningping, Harris, Angela L., Zuniga, Andy M., Mikule, Keith, Tremblay, Martin, Jiang, Yongying, Mahendra, Mikhila, Pang, Jihai, Wu, Qi, Xu, Quanyun, Heffernan, Timothy P., Jones, Philip, Lewis, Richard T.

Volltext

How Can I Help My Child Get Ready to Read? von Rogers, Norma

Volltext bestellen

What Books and Records Should I Get for My Preschooler? von Rogers, Norma

Volltext bestellen

Abstract LB-071: Discovery of an imidazopyridine series of potent human IDO1 inhibitors with robust target engagement in a preclinical tumor model von Petrocchi, Alessia, Reyna, Naphtali J., Mseeh, Faika, Parker, Connor A., Yu, Simon, Xu, Quanyun, Feng, Ningping, Leonard, Paul, Rogers, Norma, Cross, Jason B., Harris, Angela L., Jiang, Yongying, Khor, Tin Oo, Mahendra, Mikhila G., Pang, Jihai, Wu, Qi, Zuniga, Andy M., McAfoos, Timothy, Hamilton, Matthew M., Marszalek, Joe R., Mikule, Keith, Vancutsem, Paul, Wilcoxen, Keith, Tremblay, Martin, Jones, Philip, Lewis, Richard T.

Volltext

Abstract 1023: Functional genomics reveals dependency on 6-phosphogluconate dehydrogenase in OXPHOS-deficient tumors von Sun, Yuting, Bandi, Madhavi, Lofton, Timothy, Smith, Melinda, Bristow, Christopher, Rogers, Norma, Edward, Chang, Geck Do, Mary, Jiang, Yongying, Morlacchi, Pietro, Muller, Florian, Mseeh, Faika, Czako, Barbara, Palmer, Wylie, Toniatti, Carlo, Jones, Philip, Draetta, Giulio, Heffernan, Timothy, Marszalek, Joseph

Volltext

Pregnant and Parenting Women with a Substance Use Disorder: Actions and Policy for Enduring Therapeutic Practice von Jessup, Martha A., Oerther, Sarah E., Gance-Cleveland, Bonnie, Cleveland, Lisa M., Czubaruk, Kim M., Byrne, Mary W., D'Apolito, Karen, Adams, Susan M., Braxter, Betty J., Martinez-Rogers, Norma

Volltext

Gender differences of inducible nitric oxide production in SJL/J mice with experimental autoimmune encephalomyelitis von Ding, Minzhen, Wong, Joyce L, Rogers, Norma E, Ignarro, Louis J, Voskuhl, Rhonda R

Volltext

Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation von Tegley, Christopher M., Viswanadhan, Vellarkad N., Biswas, Kaustav, Frohn, Michael J., Peterkin, Tanya A.N., Chang, Catherine, Bürli, Roland W., Dao, Jennifer H., Veith, Henrike, Rogers, Norma, Yoder, Sean C., Biddlecome, Gloria, Tagari, Philip, Allen, Jennifer R., Hungate, Randall W.

Volltext

Nurse's Role in the Prevention of Cervical Cancer Among Underserved and Minority Populations von Rogers, Norma Martinez, Cantu, Adelita G

Volltext

Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1α prolyl hydroxylase-2 inhibitors von Frohn, Mike, Viswanadhan, Vellarkad, Pickrell, Alexander J., Golden, Jennifer E., Muller, Kristine M., Bürli, Roland W., Biddlecome, Gloria, Yoder, Sean C., Rogers, Norma, Dao, Jennifer H., Hungate, Randall, Allen, Jennifer R.

Volltext