Itaconate confers tolerance to late NLRP3 inflammasome activation von Bambouskova, Monika, Potuckova, Lucie, Paulenda, Tomas, Kerndl, Martina, Mogilenko, Denis A., Lizotte, Kate, Swain, Amanda, Hayes, Sebastian, Sheldon, Ryan D., Kim, Hyeryun, Kapadnis, Unnati, Ellis, Abigail E., Isaguirre, Christine, Burdess, Samantha, Laha, Anwesha, Amarasinghe, Gaya K., Chubukov, Victor, Roddy, Thomas P., Diamond, Michael S., Jones, Russell G., Simons, Donald M., Artyomov, Maxim N.

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Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells von Ma, Eric H., Verway, Mark J., Johnson, Radia M., Roy, Dominic G., Steadman, Mya, Hayes, Sebastian, Williams, Kelsey S., Sheldon, Ryan D., Samborska, Bozena, Kosinski, Penelope A., Kim, Hyeryun, Griss, Takla, Faubert, Brandon, Condotta, Stephanie A., Krawczyk, Connie M., DeBerardinis, Ralph J., Stewart, Kelly M., Richer, Martin J., Chubukov, Victor, Roddy, Thomas P., Jones, Russell G.

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Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis von Bambouskova, Monika, Gorvel, Laurent, Lampropoulou, Vicky, Sergushichev, Alexey, Loginicheva, Ekaterina, Johnson, Kendall, Korenfeld, Daniel, Mathyer, Mary Elizabeth, Kim, Hyeryun, Huang, Li-Hao, Duncan, Dustin, Bregman, Howard, Keskin, Abdurrahman, Santeford, Andrea, Apte, Rajendra S., Sehgal, Raghav, Johnson, Britney, Amarasinghe, Gaya K., Soares, Miguel P., Satoh, Takashi, Akira, Shizuo, Hai, Tsonwin, de Guzman Strong, Cristina, Auclair, Karine, Roddy, Thomas P., Biller, Scott A., Jovanovic, Marko, Klechevsky, Eynav, Stewart, Kelly M., Randolph, Gwendalyn J., Artyomov, Maxim N.

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Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming von Roy, Dominic G., Chen, Jocelyn, Mamane, Victoria, Ma, Eric H., Muhire, Brejnev M., Sheldon, Ryan D., Shorstova, Tatiana, Koning, Rutger, Johnson, Radia M., Esaulova, Ekaterina, Williams, Kelsey S., Hayes, Sebastian, Steadman, Mya, Samborska, Bozena, Swain, Amanda, Daigneault, Audrey, Chubukov, Victor, Roddy, Thomas P., Foulkes, William, Pospisilik, J. Andrew, Bourgeois-Daigneault, Marie-Claude, Artyomov, Maxim N., Witcher, Michael, Krawczyk, Connie M., Larochelle, Catherine, Jones, Russell G.

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Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages von Swain, Amanda, Bambouskova, Monika, Kim, Hyeryun, Andhey, Prabhakar Sairam, Duncan, Dustin, Auclair, Karine, Chubukov, Victor, Simons, Donald M., Roddy, Thomas P., Stewart, Kelly M., Artyomov, Maxim N.

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Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer von Best, Sarah A., Gubser, Patrick M., Sethumadhavan, Shalini, Kersbergen, Ariena, Negrón Abril, Yashira L., Goldford, Joshua, Sellers, Katherine, Abeysekera, Waruni, Garnham, Alexandra L., McDonald, Jackson A., Weeden, Clare E., Anderson, Dovile, Pirman, David, Roddy, Thomas P., Creek, Darren J., Kallies, Axel, Kingsbury, Gillian, Sutherland, Kate D.

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Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study von Neeland, Ian J., Singh, Shruti, McGuire, Darren K., Vega, Gloria L., Roddy, Thomas, Reilly, Dermot F., Castro-Perez, Jose, Kozlitina, Julia, Scherer, Philipp E.

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Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort von Kozlitina, Julia, Zhou, Haihong, Brown, Patricia N, Rohm, Rory J, Pan, Yi, Ayanoglu, Gulesi, Du, Xiaoyan, Rimmer, Eric, Reilly, Dermot F, Roddy, Thomas P, Cully, Doris F, Vogt, Thomas F, Blom, Daniel, Hoek, Maarten

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DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates von McLaren, David G., Han, Seongah, Murphy, Beth Ann, Wilsie, Larissa, Stout, Steven J., Zhou, Haihong, Roddy, Thomas P., Gorski, Judith N., Metzger, Daniel E., Shin, Myung K., Reilly, Dermot F., Zhou, Heather H., Tadin-Strapps, Marija, Bartz, Steven R., Cumiskey, Anne-Marie, Graham, Thomas H., Shen, Dong-Ming, Akinsanya, Karen O., Previs, Stephen F., Imbriglio, Jason E., Pinto, Shirly

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Preclinical toxicology profile of squalene epoxidase inhibitors von Nagaraja, Raj, Olaharski, Andrew, Narayanaswamy, Rohini, Mahoney, Christopher, Pirman, David, Gross, Stefan, Roddy, Thomas P., Popovici-Muller, Janeta, Smolen, Gromoslaw A., Silverman, Lee

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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition von Mahoney, Christopher E., Pirman, David, Chubukov, Victor, Sleger, Taryn, Hayes, Sebastian, Fan, Zi Peng, Allen, Eric L., Chen, Ying, Huang, Lingling, Liu, Meina, Zhang, Yingjia, McDonald, Gabrielle, Narayanaswamy, Rohini, Choe, Sung, Chen, Yue, Gross, Stefan, Cianchetta, Giovanni, Padyana, Anil K., Murray, Stuart, Liu, Wei, Marks, Kevin M., Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Nagaraja, Nelamangala, Biller, Scott A., Roddy, Thomas, Popovici-Muller, Janeta, Smolen, Gromoslaw A.

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Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters von Castro-Perez, Jose, Briand, François, Gagen, Karen, Wang, Sheng-Ping, Chen, Ying, McLaren, David G., Shah, Vinit, Vreeken, Rob J., Hankemeier, Thomas, Sulpice, Thierry, Roddy, Thomas P., Hubbard, Brian K., Johns, Douglas G.

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Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery von Jahnke, Wolfgang, Rondeau, Jean-Michel, Cotesta, Simona, Marzinzik, Andreas, Pellé, Xavier, Geiser, Martin, Strauss, André, Götte, Marjo, Bitsch, Francis, Hemmig, René, Henry, Chrystèle, Lehmann, Sylvie, Glickman, J Fraser, Roddy, Thomas P, Stout, Steven J, Green, Jonathan R

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Rapid, Selective, and Sensitive Method for Semitargeted Discovery of Congeneric Natural Products by Liquid Chromatography Tandem Mass Spectrometry von Herath, Kithsiri B, Previs, Stephen F, Roddy, Thomas P, Attygalle, Athula B, González, Ignacio, Genilloud, Olga, Singh, Sheo B

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Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma von Shah, Vinit, Castro-Perez, Jose M., McLaren, David G., Herath, Kithsiri B., Previs, Stephen F., Roddy, Thomas P.

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Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S] von Yin, Wu, Carballo-Jane, Ester, McLaren, David G., Mendoza, Vivienne H., Gagen, Karen, Geoghagen, Neil S., McNamara, Lesley Ann, Gorski, Judith N., Eiermann, George J., Petrov, Aleksandr, Wolff, Michael, Tong, Xinchun, Wilsie, Larissa C., Akiyama, Taro E., Chen, Jing, Thankappan, Anil, Xue, Jiyan, Ping, Xiaoli, Andrews, Genevieve, Wickham, L. Alexandra, Gai, Cesaire L., Trinh, Tu, Kulick, Alison A., Donnelly, Marcie J., Voronin, Gregory O., Rosa, Ray, Cumiskey, Anne-Marie, Bekkari, Kavitha, Mitnaul, Lyndon J., Puig, Oscar, Chen, Fabian, Raubertas, Richard, Wong, Peggy H., Hansen, Barbara C., Koblan, Ken S., Roddy, Thomas P., Hubbard, Brian K, Strack, Alison M.

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Localization of Fatty Acyl and Double Bond Positions in Phosphatidylcholines Using a Dual Stage CID Fragmentation Coupled with Ion Mobility Mass Spectrometry von Castro-Perez, Jose, Roddy, Thomas P., Nibbering, Nico M. M., Shah, Vinit, McLaren, David G., Previs, Stephen, Attygalle, Athula B., Herath, Kithsiri, Chen, Zhu, Wang, Sheng-Ping, Mitnaul, Lyndon, Hubbard, Brian K., Vreeken, Rob J., Johns, Douglas G., Hankemeier, Thomas

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Simultaneous quantitation and size characterization of apolipoprotein(a) by ultra-performance liquid chromatography/mass spectrometry von Lassman, Michael E., McLaughlin, Theresa M., Zhou, Haihong, Pan, Yi, Marcovina, Santica M., Laterza, Omar, Roddy, Thomas P.

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Using [ 2 H]water to quantify the contribution of de novo palmitate synthesis in plasma: enabling back-to-back studies von Previs, Stephen F, Herath, Kithsiri, Nawrocki, Andrea R, Rodriguez, Carlos G, Slipetz, Deborah, Singh, Sheo B, Kang, Ling, Bhat, Gowri, Roddy, Thomas P, Conarello, Stacey, Terebetski, Jenna, Erion, Mark D, Kelley, David E

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Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS[S] von Pan, Yi, Zhou, Haihong, Mahsut, Ablatt, Rohm, Rory J., Berejnaia, Olga, Price, Olga, Chen, Ying, Castro-Perez, Jose, Lassman, Michael E., McLaren, David, Conway, James, Jensen, Kristian K., Thomas, Tiffany, Reyes-Soffer, Gissette, Ginsberg, Henry N., Gutstein, David E., Cleary, Michele, Previs, Stephen F., Roddy, Thomas P.

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