Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field von Wang, Lingle, Wu, Yujie, Deng, Yuqing, Kim, Byungchan, Pierce, Levi, Krilov, Goran, Lupyan, Dmitry, Robinson, Shaughnessy, Dahlgren, Markus K, Greenwood, Jeremy, Romero, Donna L, Masse, Craig, Knight, Jennifer L, Steinbrecher, Thomas, Beuming, Thijs, Damm, Wolfgang, Harder, Ed, Sherman, Woody, Brewer, Mark, Wester, Ron, Murcko, Mark, Frye, Leah, Farid, Ramy, Lin, Teng, Mobley, David L, Jorgensen, William L, Berne, Bruce J, Friesner, Richard A, Abel, Robert

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Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy von Kelly, Priscilla N, Romero, Donna L, Yang, Yibin, Shaffer, 3rd, Arthur L, Chaudhary, Divya, Robinson, Shaughnessy, Miao, Wenyan, Rui, Lixin, Westlin, William F, Kapeller, Rosana, Staudt, Louis M

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Design of Selective, ATP-Competitive Inhibitors of Akt von Freeman-Cook, Kevin D, Autry, Christopher, Borzillo, Gary, Gordon, Deborah, Barbacci-Tobin, Elsa, Bernardo, Vincent, Briere, David, Clark, Tracey, Corbett, Matthew, Jakubczak, John, Kakar, Shefali, Knauth, Elizabeth, Lippa, Blaise, Luzzio, Michael J, Mansour, Mahmoud, Martinelli, Gary, Marx, Matthew, Nelson, Kendra, Pandit, Jayvardhan, Rajamohan, Francis, Robinson, Shaughnessy, Subramanyam, Chakrapani, Wei, Liuqing, Wythes, Martin, Morris, Joel

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Synthesis and structure based optimization of novel Akt inhibitors von Lippa, Blaise, Pan, Gonghua, Corbett, Matthew, Li, Chao, Kauffman, Goss S., Pandit, Jayvardhan, Robinson, Shaughnessy, Wei, Liuqing, Kozina, Ekaterina, Marr, Eric S., Borzillo, Gary, Knauth, Elisabeth, Barbacci-Tobin, Elsa G., Vincent, Patrick, Troutman, Merin, Baker, Deborah, Rajamohan, Francis, Kakar, Shefali, Clark, Tracey, Morris, Joel

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Recent advances in the discovery of small molecule inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4) as a therapeutic target for inflammation and oncology disorders von Chaudhary, Divya, Robinson, Shaughnessy, Romero, Donna L

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Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors von Kuhn, Bernd, Tichý, Michal, Wang, Lingle, Robinson, Shaughnessy, Martin, Rainer E, Kuglstatter, Andreas, Benz, Jörg, Giroud, Maude, Schirmeister, Tanja, Abel, Robert, Diederich, François, Hert, Jérôme

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Recent Advances in the Discovery of Small Molecule Inhibitors of Interleukin‑1 Receptor-Associated Kinase 4 (IRAK4) as a Therapeutic Target for Inflammation and Oncology Disorders:... von Chaudhary, Divya, Robinson, Shaughnessy, Romero, Donna L.

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Abstract LB-112: Highly potent and selective interleukin-1 receptor-associated kinase 4 inhibitors for the therapy of lymphoid malignancies von Kelly, Priscilla N., Chaudhary, Divya, Young, Ryan M., Shaffer, Art, Robinson, Shaughnessy, Romero, Donna L., Kapeller, Rosana, Staudt, Louis M.

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IRAK4 Kinase As A Novel Therapeutic Target in the ABC Subtype of Diffuse Large B Cell Lymphoma von Lim, Kian-Huat, Romero, Donna L., Chaudhary, Divya, Robinson, Shaughnessy D., Staudt, Louis M.

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Structure–activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors von Laha, Joydev K., Zhang, Xuemei, Qiao, Lixin, Liu, Min, Chatterjee, Snigdha, Robinson, Shaughnessy, Kosik, Kenneth S., Cuny, Gregory D.

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Synergistic Blockade Of Activated B Cell-Like DLBCL Proliferation With a Selective Inhibitor Of IRAK4 In Combination With Inhibition Of The B-Cell Receptor Signaling Network von Chaudhary, Divya, Wood, Nancy, Romero, Donna L., Robinson, Shaughnessy D., Greenwood, Jeremy R, Shelley, Mee, Morin, Michael, Kapeller, Rosana, Westlin, William F

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Effect Of MYD88 Mutation In CLL On IRAK4 and BTK Inhibition In Vitro von Tesar, Bethany, Chaudhary, Divya, Werner, Lillian, Improgo, Reina, Pochet, Nathalie, Fernandes, Stacey M, Hoang, Kevin, Vartanov, Alexander R., Romero, Donna L., Robinson, Shaughnessy D., Neuberg, Donna S., Westlin, William F., Brown, Jennifer R.

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Corrections to Design of Selective, ATP-Competitive Inhibitors of Akt von Freeman-Cook, Kevin D, Autry, Christopher, Borzillo, Gary, Gordon, Deborah, Barbacci-Tobin, Elsa, Bernardo, Vincent, Briere, David, Clark, Tracey, Corbett, Matthew, Jakubczak, John, Kakar, Shefali, Knauth, Elizabeth, Lippa, Blaise, Luzzio, Michael J, Mansour, Mahmoud, Martinelli, Gary, Marx, Matthew, Nelson, Kendra, Pandit, Jayvardhan, Rajamohan, Francis, Robinson, Shaughnessy, Subramanyam, Chakrapani, Wei, Liuqing, Wythes, Martin, Morris, Joel

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Solid phase synthesis of guanidines von Robinson, Shaughnessy, Roskamp, Eric J.

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Indole Resin:  A Versatile New Support for the Solid-Phase Synthesis of Organic Molecules von Estep, Kimberly G, Neipp, Christopher E, Stephens Stramiello, Linda M, Adam, Mavis D, Allen, Martin P, Robinson, Shaughnessy, Roskamp, Eric J

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CTPS1 INHIBITORS AND USES THEREOF von VERRAS, Andreas, WEST, Angela V, CAMPOS, Sebastien, WHITEHEAD, Lewis, ALBANESE, Steven K, KAILA, Neelu, KREUTTER, Kevin D, DEMARCO, Kevin, ROBINSON, Shaughnessy

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CTPS1 INHIBITORS AND USES THEREOF von VERRAS, Andreas, WEST, Angela V, CAMPOS, Sebastien, WHITEHEAD, Lewis, ALBANESE, Steven K, KAILA, Neelu, KREUTTER, Kevin D, DEMARCO, Kevin, ROBINSON, Shaughnessy

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CTPS1 INHIBITORS AND USES THEREOF von Verras, Andreas, Campos, Sebastien, Kaila, Neelu, Whitehead, Lewis, Robinson, Shaughnessy, West, Angela V, Demarco, Kevin, Albanese, Steven K, KREUTTER, Kevin D

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TYK2 INHIBITORS AND USES THEREOF von HARRIMAN, Geraldine C, MASSE, Craig E, ROMERO, Donna L, DAHLGREN, Markus, GREENWOOD, Jeremy Robert, WESTER, Ronald T, SHELLEY, Mee, MONDAL, Sayan, ROBINSON, Shaughnessy, KENNEDY-SMITH, Joshua Jahmil

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TYK2 inhibitors and uses thereof von Greenwood, Jeremy Robert, Kennedy-Smith, Joshua Jahmil, Masse, Craig E, Shelley, Mee, Romero, Donna L, Dahlgren, Markus, Robinson, Shaughnessy, Harriman, Geraldine C, Wester, Ronald T, Mondal, Sayan

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