Cytochrome c Release from Mitochondria Proceeds by a Two-Step Process von Ott, Martin, Robertson, John D., Gogvadze, Vladimir, Zhivotovsky, Boris, Orrenius, Sten

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Different Signaling Pathways Stimulate a Disintegrin and Metalloprotease-17 (ADAM17) in Neutrophils during Apoptosis and Activation von Wang, Yue, Robertson, John D., Walcheck, Bruce

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BH3-only protein BIM mediates heat shock-induced apoptosis von Mahajan, Indra M, Chen, Miao-Der, Muro, Israel, Robertson, John D, Wright, Casey W, Bratton, Shawn B

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Molecular Mechanisms of Apoptosis Induced by Cytotoxic Chemicals von Robertson, John D., Orrenius, Sten

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KU135, a Novel Novobiocin-Derived C-Terminal Inhibitor of the 90-kDa Heat Shock Protein, Exerts Potent Antiproliferative Effects in Human Leukemic Cells von Shelton, Shary N, Shawgo, Mary E, Matthews, Shawna B, Lu, Yuanming, Donnelly, Alison C, Szabla, Kristen, Tanol, Mehmet, Vielhauer, George A, Rajewski, Roger A, Matts, Robert L, Blagg, Brian S J, Robertson, John D

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Caspase-mediated Bak Activation and Cytochrome c Release during Intrinsic Apoptotic Cell Death in Jurkat Cells von Shawgo, Mary E., Shelton, Shary N., Robertson, John D.

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Cleavage of Bid by Executioner Caspases Mediates Feed Forward Amplification of Mitochondrial Outer Membrane Permeabilization during Genotoxic Stress-induced Apoptosis in Jurkat Cel... von Shelton, Shary N., Shawgo, Mary E., Robertson, John D.

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Caspase-2 Permeabilizes the Outer Mitochondrial Membrane and Disrupts the Binding of Cytochrome c to Anionic Phospholipids von Enoksson, Mari, Robertson, John D., Gogvadze, Vladimir, Bu, Pengli, Kropotov, Andrey, Zhivotovsky, Boris, Orrenius, Sten

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Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity von Robertson, John D, Gogvadze, Vladimir, Kropotov, Andrey, Vakifahmetoglu, Helin, Zhivotovsky, Boris, Orrenius, Sten

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Caspase-9 Activation by the Apoptosome Is Not Required for Fas-mediated Apoptosis in Type II Jurkat Cells von Shawgo, Mary E., Shelton, Shary N., Robertson, John D.

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Requirement of Apaf-1 for mitochondrial events and the cleavage or activation of all procaspases during genotoxic stress-induced apoptosis von Franklin, Emily E, Robertson, John D

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Computationally modeling mammalian succinate dehydrogenase kinetics identifies the origins and primary determinants of ROS production von Manhas, Neeraj, Duong, Quynh V., Lee, Pilhwa, Richardson, Joshua D., Robertson, John D., Moxley, Michael A., Bazil, Jason N.

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Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis von Robertson, John D, Enoksson, Mari, Suomela, Minna, Zhivotovsky, Boris, Orrenius, Sten

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Differential regulation of the mitochondrial and death receptor pathways in neural stem cells von Tamm, Christoffer, Robertson, John D., Sleeper, Eric, Enoksson, Mari, Emgård, Mia, Orrenius, Sten, Ceccatelli, Sandra

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Activation of Caspase-9, but Not Caspase-2 or Caspase-8, Is Essential for Heat-induced Apoptosis in Jurkat Cells von Shelton, Shary N., Dillard, Cindy D., Robertson, John D.

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Cytochrome c Release Occurs via Ca2+-dependent and Ca2+-independent Mechanisms That Are Regulated by Bax von Gogvadze, Vladimir, Robertson, John D., Zhivotovsky, Boris, Orrenius, Sten

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Role of mitochondria in toxic cell death von Robertson, John D, Orrenius, Sten

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Requirement of Apoptotic Protease-Activating Factor-1 for Bortezomib-Induced Apoptosis but Not for Fas-Mediated Apoptosis in Human Leukemic Cells von Ottosson-Wadlund, Astrid, Ceder, Rebecca, Preta, Giulio, Pokrovskaja, Katja, Grafström, Roland C., Heyman, Mats, Söderhäll, Stefan, Grandér, Dan, Hedenfalk, Ingrid, Robertson, John D., Fadeel, Bengt

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New Methodology Is a Key to Progress von Robertson, John D., Zhivotovsky, Boris

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Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition von Gogvadze, Vladimir, Robertson, John D, Enoksson, Mari, Zhivotovsky, Boris, Orrenius, Sten

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