The Hedgehog signal transduction network von Robbins, David J, Fei, Dennis Liang, Riobo, Natalia A

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Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA) von Green, Benjamin B, Karagas, Margaret R, Punshon, Tracy, Jackson, Brian P, Robbins, David J, Houseman, E Andres, Marsit, Carmen J

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Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis von Li, Bin, Flaveny, Colin A, Giambelli, Camilla, Fei, Dennis Liang, Han, Lu, Hang, Brian I, Bai, Feng, Pei, Xin-Hai, Nose, Vania, Burlingame, Oname, Capobianco, Anthony J, Orton, Darren, Lee, Ethan, Robbins, David J

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Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro von You, Min, PhD, Varona-Santos, Javier, PhD, Singh, Samer, PhD, Robbins, David J., PhD, Savaraj, Niramol, MD, Nguyen, Dao M., MD, MSc, FRCSC, FACS

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Opioids Impair Intestinal Epithelial Repair in HIV-Infected Humanized Mice von Meng, Jingjing, Banerjee, Santanu, Zhang, Li, Sindberg, Greg, Moidunny, Shamsudheen, Li, Bin, Robbins, David J, Girotra, Mohit, Segura, Bradley, Ramakrishnan, Sundaram, Roy, Sabita

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling von Shen, Chen, Nayak, Anmada, Neitzel, Leif R., Adams, Amber A., Silver-Isenstadt, Maya, Sawyer, Leah M., Benchabane, Hassina, Wang, Huilan, Bunnag, Nawat, Li, Bin, Wynn, Daniel T., Yang, Fan, Garcia-Contreras, Marta, Williams, Charles H., Dakshanamurthy, Sivanesan, Hong, Charles C., Ayad, Nagi G., Capobianco, Anthony J., Ahmed, Yashi, Lee, Ethan, Robbins, David J.

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The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis von Astudillo, Luisana, Da Silva, Thiago G, Wang, Zhiqiang, Han, Xiaoqing, Jin, Ke, VanWye, Jeffrey, Zhu, Xiaoxia, Weaver, Kelly, Oashi, Taiji, Lopes, Pedro E M, Orton, Darren, Neitzel, Leif R, Lee, Ethan, Landgraf, Ralf, Robbins, David J, MacKerell, Jr, Alexander D, Capobianco, Anthony J

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The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6 von Spencer, Zachary T., Ng, Victoria H., Benchabane, Hassina, Siddiqui, Ghalia Saad, Duwadi, Deepesh, Maines, Ben, Bryant, Jamal M., Schwarzkopf, Anna, Yuan, Kai, Kassel, Sara N., Mishra, Anant, Pimentel, Ashley, Lebensohn, Andres M., Rohatgi, Rajat, Gerber, Scott A., Robbins, David J., Lee, Ethan, Ahmed, Yashi

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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling von Ng, Victoria H., Spencer, Zachary, Neitzel, Leif R., Nayak, Anmada, Loberg, Matthew A., Shen, Chen, Kassel, Sara N., Kroh, Heather K., An, Zhenyi, Anthony, Christin C., Bryant, Jamal M., Lawson, Amanda, Goldsmith, Lily, Benchabane, Hassina, Hansen, Amanda G., Li, Jingjing, D’Souza, Starina, Lebensohn, Andres M., Rohatgi, Rajat, Weiss, William A., Weiss, Vivian L., Williams, Charles, Hong, Charles C., Robbins, David J., Ahmed, Yashi, Lee, Ethan

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Pyrvinium Attenuates Hedgehog Signaling Downstream of Smoothened von BIN LI, LIANG FEI, Dennis, ORTON, Darren, LU HAN, BAOLIN WANG, CAPOBIANCO, Anthony J, ETHAN LEE, ROBBINS, David J, FLAVENY, Colin A, DAHMANE, Nadia, BAUBET, Valérie, ZHIQIANG WANG, FENG BAI, PEI, Xin-Hai, RODRIGUEZ-BIANCO, Jezabel, BRIAN HANG

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Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis von Penas, Clara, Maloof, Marie E., Stathias, Vasileios, Long, Jun, Tan, Sze Kiat, Mier, Jose, Fang, Yin, Valdes, Camilo, Rodriguez-Blanco, Jezabel, Chiang, Cheng-Ming, Robbins, David J., Liebl, Daniel J., Lee, Jae K., Hatten, Mary E., Clarke, Jennifer, Ayad, Nagi G.

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Transcriptome-wide analysis of changes in the fetal placenta associated with prenatal arsenic exposure in the New Hampshire Birth Cohort Study von Winterbottom, Emily F, Ban, Yuguang, Sun, Xiaodian, Capobianco, Anthony J, Marsit, Carmen J, Chen, Xi, Wang, Lily, Karagas, Margaret R, Robbins, David J

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Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma von Wang, Zhiqiang, Da Silva, Thiago G, Jin, Ke, Han, Xiaoqing, Ranganathan, Prathibha, Zhu, Xiaoxia, Sanchez-Mejias, Avencia, Bai, Feng, Li, Bin, Fei, Dennis Liang, Weaver, Kelly, Carpio, Rodrigo Vasquez-Del, Moscowitz, Anna E, Koshenkov, Vadim P, Sanchez, Lilly, Sparling, Lynne, Pei, Xin-Hai, Franceschi, Dido, Ribeiro, Afonso, Robbins, David J, Livingstone, Alan S, Capobianco, Anthony J

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NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis von Shersher, Elena, Lahiry, Mohini, Alvarez-Trotta, Annamil, Diluvio, Giulia, Robbins, David J, Shiekhattar, Ramin, Capobianco, Anthony J

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Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner von Winterbottom, Emily F, Moroishi, Yuka, Halchenko, Yuliya, Armstrong, David A, Beach, Paul J, Nguyen, Quang P, Capobianco, Anthony J, Ayad, Nagi G, Marsit, Carmen J, Li, Zhigang, Karagas, Margaret R, Robbins, David J

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Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer von Yang, Fan, Wynn, Daniel T, Shen, Chen, Ayad, Nagi G, Robbins, David J

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Identification of a Family of Fatty-Acid-Speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties von Long, Jun, Tokhunts, Robert, Old, William M., Houel, Stephane, Rodgriguez-Blanco, Jezabel, Singh, Samer, Schilling, Neal, Capobianco, Anthony J., Ahn, Natalie G., Robbins, David J.

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Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation von Anthony, Christin C, Robbins, David J, Ahmed, Yashi, Lee, Ethan

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The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression von Winterbottom, Emily F, Koestler, Devin C, Fei, Dennis Liang, Wika, Eric, Capobianco, Anthony J, Marsit, Carmen J, Karagas, Margaret R, Robbins, David J

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A Highly Conserved Amino-terminal Region of Sonic Hedgehog Is Required for the Formation of Its Freely Diffusible Multimeric Form von Goetz, John A., Singh, Samer, Suber, Liza M., Kull, F. Jon, Robbins, David J.

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