Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants von Berghmans, Stephane, Hunt, Julia, Roach, Alan, Goldsmith, Paul

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Non-Associative Learning in Larval Zebrafish von Best, Jonathan D, Berghmans, Stéphane, Hunt, Julia J F G, Clarke, Samantha C, Fleming, Angeleen, Goldsmith, Paul, Roach, Alan G

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Loss of PINK1 Function Affects Development and Results in Neurodegeneration in Zebrafish von Anichtchik, Oleg, Diekmann, Heike, Fleming, Angeleen, Roach, Alan, Goldsmith, Paul, Rubinsztein, David C

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Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects von Buckley, Clare E., Marguerie, Anita, Roach, Alan G., Goldsmith, Paul, Fleming, Angeleen, Alderton, Wendy K., Franklin, Robin J.M.

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Decreased BDNF Levels Are a Major Contributor to the Embryonic Phenotype of Huntingtin Knockdown Zebrafish von Diekmann, Heike, Anichtchik, Oleg, Fleming, Angeleen, Futter, Marie, Goldsmith, Paul, Roach, Alan, Rubinsztein, David C

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Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery von Berghmans, Stéphane, Butler, Paul, Goldsmith, Paul, Waldron, Gareth, Gardner, Iain, Golder, Zoe, Richards, Frances M., Kimber, Gillian, Roach, Alan, Alderton, Wendy, Fleming, Angeleen

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A Virtual Screening Approach to Finding Novel and Potent Antagonists at the Melanin-Concentrating Hormone 1 Receptor von Clark, David E, Higgs, Christopher, Wren, Stephen P, Dyke, Hazel J, Wong, Melanie, Norman, Dennis, Lockey, Peter M, Roach, Alan G

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Human Vascular Smooth Muscle Cells Express Receptors for CC Chemokines von Hayes, Ian M, Jordan, Nicola J, Towers, Sarah, Smith, Graham, Paterson, Jacqui R, Earnshaw, Jonothan J, Roach, Alan G, Westwick, John, Williams, Robert J

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Identification and optimisation of a series of substituted 5-(1 H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors von Price, Steve, Bordogna, Walter, Bull, Richard J., Clark, David E., Crackett, Peter H., Dyke, Hazel J., Gill, Matthew, Harris, Neil V., Gorski, Julia, Lloyd, Julia, Lockey, Peter M., Mullett, Julia, Roach, Alan G., Roussel, Fabien, White, Anne B.

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Quinazoline and benzimidazole MCH-1R antagonists von Arienzo, Rosa, Cramp, Sue, Dyke, Hazel J., Lockey, Peter M., Norman, Dennis, Roach, Alan G., Smith, Phil, Wong, Melanie, Wren, Stephen P.

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Agent-based land-use models: a review of applications von Matthews, Robin B, Gilbert, Nigel G, Roach, Alan, Polhill, J. Gary, Gotts, Nick M

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Structure–activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists von Arienzo, Rosa, Clark, David E, Cramp, Sue, Daly, Stephen, Dyke, Hazel J, Lockey, Peter, Norman, Dennis, Roach, Alan G, Stuttle, Keith, Tomlinson, Maxine, Wong, Melanie, Wren, Stephen P

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Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors von Price, Steve, Bordogna, Walter, Braganza, Ruth, Bull, Richard J., Dyke, Hazel J., Gardan, Sophie, Gill, Matthew, Harris, Neil V., Heald, Robert A., van den Heuvel, Marco, Lockey, Peter M., Lloyd, Julia, Molina, Aranzazu G., Roach, Alan G., Roussel, Fabien, Sutton, Jonathan M., White, Anne B.

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O23 Using big data in the design and validation of a simulation of the healthcare system for patients with inflammatory rheumatic disease: results from the SiMSK study von Roach, Alan R, Dennison, Elaine M, Hyrich, Kimme L, MacGregor, Alex J

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O24 The impact of early referral and lowering clinical thresholds of biologic access on the disease course and costs in RA: results from the SiMSK study von Roach, Alan R, Dennison, Elaine M, Hyrich, Kimme L, MacGregor, Alex J

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National variation in the composition of rheumatology multidisciplinary teams: a cross-sectional study von Ndosi, Mwidimi, Ferguson, Rachel, Backhouse, Michael R., Bearne, Lindsay, Ainsworth, Phillip, Roach, Alan, Dennison, Elaine, Cherry, Lindsey

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Chemokine production by human vascular smooth muscle cells: modulation by IL‐13 von Jordan, Nicola J., Watson, Malcolm L., Williams, Robert J., Roach, Alan G., Yoshimura, Teizo, Westwick, John

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O20National Variation in the Composition of Rheumatology Multidisciplinary Teams von Ferguson, Rachel, Backhouse, Michael, Bearne, Lindsay, Ndosi, Mwidimi, Dennison, Elaine, Ainsworth, Phillip, Roach, Alan, Cherry, Lindsey

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173. NATIONAL AUDIT OF BIOSIMILARS USE IN RHEUMATOLOGY DEPARTMENTS IN THE UNITED KINGDOM: RESULTS FROM THE BIOSIMILARS OBSERVATORY von Yates, Max, Chan, Chris, Roach, Alan, Lewis, Anna, Flint, Julia, Kay, Lesley, Dennison, Elaine, MacGregor, Alex J.

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Selective ETA Antagonists. 5. Discovery and Structure−Activity Relationships of Phenoxyphenylacetic Acid Derivatives von Astles, Peter C, Brown, Thomas J, Halley, Frank, Handscombe, Caroline M, Harris, Neil V, Majid, Tahir N, McCarthy, Clive, McLay, Iain M, Morley, Andrew, Porter, Barry, Roach, Alan G, Sargent, Carol, Smith, Christopher, Walsh, Roger J. A

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