Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death von Magnaghi, Paola, D'Alessio, Roberto, Valsasina, Barbara, Avanzi, Nilla, Rizzi, Simona, Asa, Daniela, Gasparri, Fabio, Cozzi, Liviana, Cucchi, Ulisse, Orrenius, Christian, Polucci, Paolo, Ballinari, Dario, Perrera, Claudia, Leone, Antonella, Cervi, Giovanni, Casale, Elena, Xiao, Yang, Wong, Chihunt, Anderson, Daniel J, Galvani, Arturo, Donati, Daniele, O'Brien, Tom, Jackson, Peter K, Isacchi, Antonella

Volltext

Evaluation of bacterial adhesion of Streptococcus mutans on dental restorative materials von Montanaro, Lucio, Campoccia, Davide, Rizzi, Simona, Donati, Maria Elena, Breschi, Lorenzo, Prati, Carlo, Arciola, Carla Renata

Volltext

Novel Thienoduocarmycin–Trastuzumab ADC Demonstrates Strong Antitumor Efficacy with Favorable Safety Profile in Preclinical Studies von Valsasina, Barbara, Orsini, Paolo, Caruso, Michele, Albanese, Clara, Ciavolella, Antonella, Cucchi, Ulisse, Fraietta, Ivan, Melillo, Nicola, Fiorentini, Francesco, Rizzi, Simona, Salsa, Matteo, Isacchi, Antonella, Gasparri, Fabio

Volltext

Evidence of a linkage between matrilin-1 gene (MATN1) and idiopathic scoliosis von Montanaro, Lucio, Parisini, Patrizio, Greggi, Tiziana, Di Silvestre, Mario, Campoccia, Davide, Rizzi, Simona, Arciola, Carla Renata

Volltext

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome von TRAZZI, Stefania, MITRUGNO, Valentina Maria, VALLI, Emanuele, FUCHS, Claudia, RIZZI, Simona, GUIDI, Sandra, PERINI, Giovanni, BARTESAGHI, Renata, CIANI, Elisabetta

Volltext

Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period von Rizzi, Simona, Bianchi, Patrizia, Guidi, Sandra, Ciani, Elisabetta, Bartesaghi, Renata

Volltext

NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies von Valsasina, Barbara, Beria, Italo, Alli, Cristina, Alzani, Rachele, Avanzi, Nilla, Ballinari, Dario, Cappella, Paolo, Caruso, Michele, Casolaro, Alessia, Ciavolella, Antonella, Cucchi, Ulisse, De Ponti, Anna, Felder, Eduard, Fiorentini, Francesco, Galvani, Arturo, Gianellini, Laura M, Giorgini, Maria L, Isacchi, Antonella, Lansen, Jaqueline, Pesenti, Enrico, Rizzi, Simona, Rocchetti, Maurizio, Sola, Francesco, Moll, Jürgen

Volltext

Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships von Polucci, Paolo, Magnaghi, Paola, Angiolini, Mauro, Asa, Daniela, Avanzi, Nilla, Badari, Alessandra, Bertrand, Jay, Casale, Elena, Cauteruccio, Silvia, Cirla, Alessandra, Cozzi, Liviana, Galvani, Arturo, Jackson, Peter K, Liu, Yichin, Magnuson, Steven, Malgesini, Beatrice, Nuvoloni, Stefano, Orrenius, Christian, Sirtori, Federico Riccardi, Riceputi, Laura, Rizzi, Simona, Trucchi, Beatrice, O’Brien, Tom, Isacchi, Antonella, Donati, Daniele, D’Alessio, Roberto

Volltext

Abstract 5163: Characterization of NMS-E194, a selective and potent PERK inhibitor with efficacy in the KMS-11 multiple myeloma von Perrera, Claudia, Pulici, Maurizio, Carenzi, Davide, Motto, Ilaria, Fasolini, Marina, Casale, Elena, Depaolini, Stefania Re, Rizzi, Simona, Asa, Daniela, Roletto, Fulvia, Bindi, Simona, Casero, Daniele, Banfi, Patrizia, Ardini, Elena, Amboldi, Nadia, Ballinari, Dario, Gasparri, Fabio, Cribioli, Sabrina, Mancini, Laura, Ciomei, Marina, Donati, Daniele, Felder, Eduard, Galvani, Arturo, Isacchi, Antonella, Valsasina, Barbara

Volltext

The Prognostic Impact of Tumor Size on Cancer-Specific and Overall Survival Among Patients With Pathologic T3a Renal Cell Carcinoma von Schiavina, Riccardo, Borghesi, Marco, Chessa, Francesco, Dababneh, Hussam, Bianchi, Lorenzo, Della Mora, Livia, Del Prete, Chiara, Longhi, Barbara, Rizzi, Simona, Fiorentino, Michelangelo, Martorana, Giuseppe, Brunocilla, Eugenio

Volltext

Abstract 734: Thienoindoles: New highly promising agents for antibody-drug conjugates generation von Caruso, Michele, Gasparri, Fabio, Valsasina, Barbara, Albanese, Clara, Beria, Italo, Candiani, Ilaria, Ciomei, Marina, Colombo, Nicoletta, Cribioli, Sabrina, Cucchi, Ulisse, Felder, Eduard, Fraietta, Ivan, Galvani, Arturo, Isacchi, Antonella, Marsiglio, Aurelio, Orsini, Paolo, Perego, Rita, Rizzi, Simona, Tomasi, Attilio, Troiani, Sonia, Visco, Carlo, Donati, Daniele

Volltext

Differing risk of cancer death among patients with lymph node metastasis after radical prostatectomy and pelvic lymph node dissection: identification of risk categories according t... von Schiavina, Riccardo, Borghesi, Marco, Brunocilla, Eugenio, Manferrari, Fabio, Fiorentino, Michelangelo, Vagnoni, Valerio, Baccos, Alessandro, Pultrone, Cristian Vincenzo, Rocca, Giovanni Christian, Rizzi, Simona, Martorana, Giuseppe

Volltext

Discovery of 2‑(Cyclohexylmethylamino)pyrimidines as a New Class of Reversible Valosine Containing Protein Inhibitors von Cervi, Giovanni, Magnaghi, Paola, Asa, Daniela, Avanzi, Nilla, Badari, Alessandra, Borghi, Daniela, Caruso, Michele, Cirla, Alessandra, Cozzi, Liviana, Felder, Eduard, Galvani, Arturo, Gasparri, Fabio, Lomolino, Antonio, Magnuson, Steven, Malgesini, Beatrice, Motto, Ilaria, Pasi, Maurizio, Rizzi, Simona, Salom, Barbara, Sorrentino, Graziella, Troiani, Sonia, Valsasina, Barbara, O’Brien, Thomas, Isacchi, Antonella, Donati, Daniele, D’Alessio, Roberto

Volltext

Abstract 2690: A novel antibody-drug conjugate directed to the ALK receptor tyrosine kinase demonstrates efficacy in models of neuroblastoma von Sano, Renata, Krytska, Kateryna, Larmour, Colleen, Ligon, Gwenda F., Lillquist, Jay S., Cucchi, Ulisse, Orsini, Paolo, Rizzi, Simona, McMahon, Gerald, Alvarado, Diego, Mosse, Yael P.

Volltext

Nodal Occult Metastases in Intermediate- and High-Risk Prostate Cancer Patients Detected Using Serial Section, Immunohistochemistry, and Real-Time Reverse Transcriptase Polymerase... von Schiavina, Riccardo, Capizzi, Elisa, Borghesi, Marco, Vagnoni, Valerio, Romagnoli, Daniele, Rocca, Giovanni Christian, Giunchi, Francesca, D'Errico, Antonietta, De Giovanni, Alessia, Rizzi, Simona, Brunocilla, Eugenio, Martorana, Giuseppe, Fiorentino, Michelangelo

Volltext

Neonatal isolation impairs neurogenesis in the dentate gyrus of the guinea pig von Rizzi, Simona, Bianchi, Patrizia, Guidi, Sandra, Ciani, Elisabetta, Bartesaghi, Renata

Volltext

Adverse Features and Competing Risk Mortality in Patients with High Risk Prostate Cancer von Vagnoni, Valerio, MD, Bianchi, Lorenzo, MD, Borghesi, Marco, MD, Pultrone, Cristian Vincenzo, MD, Dababneh, Hussam, MD, PhD, Chessa, Francesco, MD, La Manna, Gaetano, MD, Rizzi, Simona, Porreca, Angelo, Brunocilla, Eugenio, MD, Martorana, Giuseppe, MD, Schiavina, Riccardo, MD

Volltext

Phosphorylation of TCTP as a Marker for Polo-like Kinase-1 Activity In Vivo von CUCCHI, Ulisse, GIANELLINI, Laura M, GIORGINI, Maria L, CAPPELLA, Paolo, BERIA, Italo, VALSASINA, Barbara, DE PONTI, Anna, SOLA, Francesco, ALZANI, Rachele, PATTON, Veronica, PEZZONI, Alice, TROIANI, Sonia, SACCARDO, Maria B, RIZZI, Simona

Volltext

Abstract A149: NMS-P945, a highly active payload for antibody drug conjugates generation von Gasparri, Fabio, Caruso, Michele, Beria, Italo, Colombo, Nicoletta, Orsini, Paolo, Perego, Rita, Rizzi, Simona, Cucchi, Ulisse, Troiani, Sonia, Riccardi Sirtori, Federico, Albanese, Clara, Marsiglio, Aurelio, Fraietta, Ivan, Sola, Francesco, Ciomei, Marina, Cribioli, Sabrina, Visco, Carlo, Felder, Eduard Rudolf, Isacchi, Antonella, Pesenti, Enrico, Galvani, Arturo, Donati, Daniele, Valsasina, Barbara

Volltext

Differing risk of cancer death among patients with lymph node metastasis after radical prostatectomy and pelvic lymph node dissection: identification of risk categories according t... von Schiavina, Riccardo, Borghesi, Marco, Brunocilla, Eugenio, Manferrari, Fabio, Fiorentino, Michelangelo, Vagnoni, Valerio, Baccos, Alessandro, Pultrone, Cristian Vincenzo, Rocca, Giovanni Christian, Rizzi, Simona, Martorana, Giuseppe

Volltext