Structure Based Prediction of Neoantigen Immunogenicity von Riley, Timothy P, Keller, Grant L J, Smith, Angela R, Davancaze, Lauren M, Arbuiso, Alyssa G, Devlin, Jason R, Baker, Brian M

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How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire von Blevins, Sydney J., Pierce, Brian G., Singh, Nishant K., Riley, Timothy P., Wang, Yuan, Spear, Timothy T., Nishimura, Michael I., Weng, Zhiping, Baker, Brian M.

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Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design von Riley, Timothy P, Chou, Hui-Ting, Hu, Ruozhen, Bzymek, Krzysztof P, Correia, Ana R, Partin, Alexander C, Li, Danqing, Gong, Danyang, Wang, Zhulun, Yu, Xinchao, Manzanillo, Paolo, Garces, Fernando

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Geometric parameters that affect the behavior of logic-gated CAR T cells von Partin, Alexander C, Bruno, Richele, Shafaattalab, Sanam, Vander Mause, Erica, Winters, Aaron, Daris, Mark, Gahrs, Casey, Jette, Claudia A, DiAndreth, Breanna, Sandberg, Mark L, Hamburger, Agnes E, Kamb, Alexander, Riley, Timothy P

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Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features von Harmalkar, Ameya, Rao, Roshan, Richard Xie, Yuxuan, Honer, Jonas, Deisting, Wibke, Anlahr, Jonas, Hoenig, Anja, Czwikla, Julia, Sienz-Widmann, Eva, Rau, Doris, Rice, Austin J, Riley, Timothy P, Li, Danqing, Catterall, Hannah B, Tinberg, Christine E, Gray, Jeffrey J, Wei, Kathy Y

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Rational selection of building blocks for the assembly of bispecific antibodies von Gong, Danyang, Riley, Timothy P, Bzymek, Krzysztof P, Correia, Ana R, Li, Danqing, Spahr, Christopher, Robinson, John H, Case, Ryan B, Wang, Zhulun, Garces, Fernando

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Next generation Fc scaffold for multispecific antibodies von Estes, Bram, Sudom, Athena, Gong, Danyang, Whittington, Douglas A., Li, Vivian, Mohr, Christopher, Li, Danqing, Riley, Timothy P., Shi, Stone D.-H., Zhang, Jun, Garces, Fernando, Wang, Zhulun

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Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies von Li, Danqing, Partin, Alexander C., Zhao, Liangjun, Chen, Irwin, Michaels, Mark L., Wang, Zhulun, Garces, Fernando, Gong, Danyang, Riley, Timothy P.

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HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen von Mock, Jee-Young, Winters, Aaron, Riley, Timothy P., Bruno, Richele, Naradikian, Martin S., Sharma, Shruti, Jette, Claudia A., Elshimali, Ryan, Gahrs, Casey, Toledo-Warshaviak, Dora, West, Anthony P., Kamb, Alexander, Hamburger, Agnes E.

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The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics von Riley, Timothy P., Baker, Brian M.

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Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes von Singh, Nishant K, Riley, Timothy P, Baker, Sarah Catherine B, Borrman, Tyler, Weng, Zhiping, Baker, Brian M

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T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability von Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.

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Improving T Cell Receptor On-Target Specificity via Structure-Guided Design von Hellman, Lance M., Foley, Kendra C., Singh, Nishant K., Alonso, Jesus A., Riley, Timothy P., Devlin, Jason R., Ayres, Cory M., Keller, Grant L.J., Zhang, Yuting, Vander Kooi, Craig W., Nishimura, Michael I., Baker, Brian M.

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Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide–MHC complexes von Hellman, Lance M., Yin, Liusong, Wang, Yuan, Blevins, Sydney J., Riley, Timothy P., Belden, Orrin S., Spear, Timothy T., Nishimura, Michael I., Stern, Lawrence J., Baker, Brian M.

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TRPM3 expression and control of glutamate release from primary vagal afferent neurons von Ragozzino, Forrest J, Arnold, Rachel A, Fenwick, Axel J, Riley, Timothy P, Lindberg, Jonathan E M, Peterson, BreeAnne, Peters, James H

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Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex von Harris, Daniel T., Wang, Ningyan, Riley, Timothy P., Anderson, Scott D., Singh, Nishant K., Procko, Erik, Baker, Brian M., Kranz, David M.

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Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition von Ayres, Cory M, Riley, Timothy P, Corcelli, Steven A, Baker, Brian M

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Computational Modeling of T Cell Receptor Complexes von Riley, Timothy P., Singh, Nishant K., Pierce, Brian G., Weng, Zhiping, Baker, Brian M.

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A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces von Riley, Timothy P, Ayres, Cory M, Hellman, Lance M, Singh, Nishant K, Cosiano, Michael, Cimons, Jennifer M, Anderson, Michael J, Piepenbrink, Kurt H, Pierce, Brian G, Weng, Zhiping, Baker, Brian M

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Molecular properties of gp100‐reactive T‐cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells von Eby, Jonathan M., Smith, Angela R., Riley, Timothy P., Cosgrove, Cormac, Ankney, Christian M., Henning, Steven W., Paulos, Chrystal M., Garrett‐Mayer, Elizabeth, Luiten, Rosalie M., Nishimura, Michael I., Baker, Brian M., Le Poole, I. Caroline

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