Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy von Baumann, Daniel, Hägele, Tanja, Mochayedi, Julian, Drebant, Jennifer, Vent, Caroline, Blobner, Sven, Noll, Julia Han, Nickel, Irena, Schumacher, Corinna, Boos, Sophie Luise, Daniel, Aline Sophie, Wendler, Susann, Volkmar, Michael, Strobel, Oliver, Offringa, Rienk

Volltext

Cancer immunotherapy： exploiting neoepitopes von Platten, Michael, Offringa, Rienk

Volltext

Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines von Hartmann, Laura, Schröter, Philipp, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Moustafa, Mahmoud, Will, Rainer, Debus, Jürgen, Brons, Stephan, Rieken, Stefan, Eichmüller, Stefan B.

Volltext

Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia von Kenter, Gemma G, Welters, Marij J.P, Valentijn, A. Rob P.M, Lowik, Margriet J.G, Berends-van der Meer, Dorien M.A, Vloon, Annelies P.G, Essahsah, Farah, Fathers, Lorraine M, Offringa, Rienk, Drijfhout, Jan Wouter, Wafelman, Amon R, Oostendorp, Jaap, Fleuren, Gert Jan, van der Burg, Sjoerd H, Melief, Cornelis J.M

Volltext

Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line von Schröter, Philipp, Hartmann, Laura, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Eisel, David, Debus, Jürgen, Eichmüller, Stefan B., Rieken, Stefan

Volltext

Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy von Baumann, Daniel, Offringa, Rienk

Volltext

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response von Karim, Rezaul, Tummers, Bart, Meyers, Craig, Biryukov, Jennifer L, Alam, Samina, Backendorf, Claude, Jha, Veena, Offringa, Rienk, van Ommen, Gert-Jan B, Melief, Cornelis J M, Guardavaccaro, Daniele, Boer, Judith M, van der Burg, Sjoerd H

Volltext

Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires von Volkmar, Michael, Fakhr, Elham, Zens, Stefan, Bury, Alice, Offringa, Rienk, Gordon, Jessica, Huduti, Enes, Wölfel, Thomas, Wölfel, Catherine

Volltext

p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition von Baumann, Daniel, Drebant, Jennifer, Hägele, Tanja, Burger, Luisa, Serger, Clara, Lauenstein, Claudia, Dudys, Przemyslaw, Erdmann, Gerrit, Offringa, Rienk

Volltext

The enchanting canvas of CAR technology: Unveiling its wonders in non-neoplastic diseases von Shu, Jinhui, Xie, Wei, Chen, Zhaozhao, Offringa, Rienk, Hu, Yu, Mei, Heng

Volltext

Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes von Karim, Rezaul, Meyers, Craig, Backendorf, Claude, Ludigs, Kristina, Offringa, Rienk, van Ommen, Gert-Jan B, Melief, Cornelis J M, van der Burg, Sjoerd H, Boer, Judith M

Volltext

Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications von Cabo, Mariona, Offringa, Rienk, Zitvogel, Laurence, Kroemer, Guido, Muntasell, Aura, Galluzzi, Lorenzo

Volltext

Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine von WELTERS, Marij J. P, KENTER, Gemma G, JAN FLEUREN, Gert, OFFRINGA, Rienk, MELIEF, Cornelis J. M, VAN DER BURGS, Sjoerd H, PIERSMA, Sytse J, VLOON, Annelies P. G, LÖWIK, Margriet J. G, BERENDS-VAN DER MEER, Dorien M. A, DRIJFHOUT, Jan W, VALENTIJN, A. Rob P. M, WAFELMAN, Amon R, OOSTENDORP, Jaap

Volltext

CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund's Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity von Bijker, Martijn S, van den Eeden, Susan J. F, Franken, Kees L, Melief, Cornelis J. M, Offringa, Rienk, van der Burg, Sjoerd H

Volltext

T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction von Pinkert, Jessica, Boehm, Hans-Henning, Trautwein, Mark, Doecke, Wolf-Dietrich, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Carretero, Rafael, Freiberg, Christoph, Gritzan, Uwe, Luetke-Eversloh, Merlin, Golfier, Sven, Von Ahsen, Oliver, Volpin, Valentina, Sorrentino, Antonio, Rathinasamy, Anchana, Xydia, Maria, Lohmayer, Robert, Sax, Julian, Nur-Menevse, Ayse, Hussein, Abir, Stamova, Slava, Beckmann, Georg, Glueck, Julian Marius, Schoenfeld, Dorian, Weiske, Joerg, Zopf, Dieter, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp, Willuda, Joerg

Volltext

Phase I Immunotherapeutic Trial with Long Peptides Spanning the E6 and E7 Sequences of High-Risk Human Papillomavirus 16 in End-Stage Cervical Cancer Patients Shows Low Toxicity an... von Kenter, Gemma G, Welters, Marij J P, Valentijn, A Rob P M, Lowik, Margriet J G, Berends-van der Meer, Dorien M A, Vloon, Annelies P G, Drijfhout, Jan W, Wafelman, Amon R, Oostendorp, Jaap, Fleuren, Gert Jan, Offringa, Rienk, van der Burg, Sjoerd H, Melief, Cornelis J M

Volltext

Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes von Sefrin, Julian P, Hillringhaus, Lars, Mundigl, Olaf, Mann, Karin, Ziegler-Landesberger, Doris, Seul, Heike, Tabares, Gloria, Knoblauch, Dominic, Leinenbach, Andreas, Friligou, Irene, Dziadek, Sebastian, Offringa, Rienk, Lifke, Valeria, Lifke, Alexander

Volltext

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation von Bijker, Martijn S, van den Eeden, Susan J.F, Franken, Kees L, Melief, Cornelis J.M, van der Burg, Sjoerd H, Offringa, Rienk

Volltext

Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display von Wickström, Stina L, Lövgren, Tanja, Volkmar, Michael, Reinhold, Bruce, Duke-Cohan, Jonathan S, Hartmann, Laura, Rebmann, Janina, Mueller, Anja, Melief, Jeroen, Maas, Roeltje, Ligtenberg, Maarten, Hansson, Johan, Offringa, Rienk, Seliger, Barbara, Poschke, Isabel, Reinherz, Ellis L, Kiessling, Rolf

Volltext

Secretogranin II influences the assembly and function of MHC class I in melanoma von Steinfass, Tamara, Poelchen, Juliane, Sun, Qian, Mastrogiulio, Giovanni, Novak, Daniel, Vierthaler, Marlene, Pardo, Sandra, Federico, Aniello, Hüser, Laura, Hielscher, Thomas, Carretero, Rafael, Offringa, Rienk, Altevogt, Peter, Umansky, Viktor, Utikal, Jochen

Volltext