AMPK directly activates mTORC2 to promote cell survival during acute energetic stress von Kazyken, Dubek, Magnuson, Brian, Bodur, Cagri, Acosta-Jaquez, Hugo A, Zhang, Deqiang, Tong, Xin, Barnes, Tammy M, Steinl, Gabrielle K, Patterson, Nicole E, Altheim, Christopher H, Sharma, Naveen, Inoki, Ken, Cartee, Gregory D, Bridges, Dave, Yin, Lei, Riddle, Steven M, Fingar, Diane C

Volltext

The IKK‐related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists von Bodur, Cagri, Kazyken, Dubek, Huang, Kezhen, Ekim Ustunel, Bilgen, Siroky, Kate A, Tooley, Aaron Seth, Gonzalez, Ian E, Foley, Daniel H, Acosta‐Jaquez, Hugo A, Barnes, Tammy M, Steinl, Gabrielle K, Cho, Kae‐Won, Lumeng, Carey N, Riddle, Steven M, Myers, Martin G, Fingar, Diane C

Volltext

Pharmacological targeting of the pseudokinase Her3 von Xie, Ting, Lim, Sang Min, Westover, Kenneth D, Dodge, Michael E, Ercan, Dalia, Ficarro, Scott B, Udayakumar, Durga, Gurbani, Deepak, Tae, Hyun Seop, Riddle, Steven M, Sim, Taebo, Marto, Jarrod A, Jänne, Pasi A, Crews, Craig M, Gray, Nathanael S

Volltext

Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation von Hermanson, Spencer B, Carlson, Coby B, Riddle, Steven M, Zhao, Jing, Vogel, Kurt W, Nichols, R Jeremy, Bi, Kun

Volltext

Pharmacological targeting of the pseudokinase Her3 von Xie, Ting, Lim, Sang Min, Westover, Kenneth D, Dodge, Michael E, Ercan, Dalia, Ficarro, Scott B, Udayakumar, Durga, Gurbani, Deepak, Tae, Hyun Seop, Riddle, Steven M, Sim, Taebo, Marto, Jarrod A, Jänne, Pasi A, Crews, Craig M, Gray, Nathanael S

Volltext

Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays von Anand, Vasanti S, Reichling, Laurie J, Lipinski, Kerri, Stochaj, Wayne, Duan, Weili, Kelleher, Kerry, Pungaliya, Pooja, Brown, Eugene L, Reinhart, Peter H, Somberg, Richard, Hirst, Warren D, Riddle, Steven M, Braithwaite, Steven P

Volltext

Structural basis for the specificity of ubiquitin C-terminal hydrolases von Johnston, S.C, Riddle, S.M, Cohen, R.E, Hill, C.P

Volltext

Leucine-rich repeat kinase 2 mutants I2020T and G2019S exhibit altered kinase inhibitor sensitivity von Reichling, Laurie J., Riddle, Steven M.

Volltext

Threshold Levels of ABL Tyrosine Kinase Inhibitors Retained in Chronic Myeloid Leukemia Cells Determine Their Commitment to Apoptosis von O'HARE, Thomas, EIDE, Christopher A, RIDDLE, Steven M, MARKS, Bryan D, VOGEI, Kurt W, KOOP, Dennis R, APGAR, John, TYNER, Jeffrey W, DEININGER, Michael W, DRUKER, Brian J, AGARWAL, Anupriya, ADRIAN, Lauren T, ZABRISKIE, Matthew S, MACKENZIE, Ryan J, LATOCHA, Dorian H, JOHNSON, Kara J, HUIHONG YOU, LUO, Jenny

Volltext

Investigation of leucine‐rich repeat kinase 2 von Anand, Vasanti S., Reichling, Laurie J., Lipinski, Kerri, Stochaj, Wayne, Duan, Weili, Kelleher, Kerry, Pungaliya, Pooja, Brown, Eugene L., Reinhart, Peter H., Somberg, Richard, Hirst, Warren D., Riddle, Steven M., Braithwaite, Steven P.

Volltext

Development and Applications of a Broad-Coverage, TR-FRET-Based Kinase Binding Assay Platform von Lebakken, Connie S., Riddle, Steven M., Singh, Upinder, Frazee, W. Jack, Eliason, Hildegard C., Gao, Yi, Reichling, Laurie J., Marks, Bryan D., Vogel, Kurt W.

Volltext

Time-resolved fluorescence resonance energy transfer kinase assays using physiological protein substrates: Applications of terbium–fluorescein and terbium–green fluorescent protein... von Riddle, Steven M., Vedvik, Kevin L., Hanson, George T., Vogel, Kurt W.

Volltext

Detection of Allosteric Kinase Inhibitors by Displacement of Active Site Probes von Lebakken, Connie S., Reichling, Laurie J., Ellefson, Jason M., Riddle, Steven M.

Volltext

A substrate for deubiquitinating enzymes based on time-resolved fluorescence resonance energy transfer between terbium and yellow fluorescent protein von Horton, Robert A., Strachan, Elizabeth A., Vogel, Kurt W., Riddle, Steven M.

Volltext

The Androgen Receptor T877A Mutant Recruits LXXLL and FXXLF Peptides Differently than Wild-Type Androgen Receptor in a Time-Resolved Fluorescence Resonance Energy Transfer Assay von Ozers, Mary Szatkowski, Marks, Bryan D, Gowda, Krishne, Kupcho, Kevin R, Ervin, Kerry M, De Rosier, Therese, Qadir, Naveeda, Eliason, Hildegard C, Riddle, Steven M, Shekhani, Mohammed Saleh

Volltext

A Substrate-Independent TR-FRET Histone Deacetylase Inhibitor Assay von Marks, Bryan D., Fakhoury, Stephen A., Frazee, William J., Eliason, Hildegard C., Riddle, Steven M.

Volltext

Pharmacological Characterization of Purified Recombinant mTOR FRB-Kinase Domain Using Fluorescence-Based Assays von Reichling, Laurie J., Lebakken, Connie S., Riddle, Steven M., Vedvik, Kevin L., Robers, Matthew B., Kopp, Leisha M., Bruinsma, Rica, Vogel, Kurt W.

Volltext

Abstract 3688: A flexible kinase inhibitor assay for active, non-activated, and impure kinase preparations von Riddle, Steven, Lebakken, Connie, Ellefson, Jason, Reichling, Laurie, Wolken, Jill

Volltext

Abstract C95: A flexible kinase inhibitor assay platform for active, nonactivated, and impure kinase preparations von Lebakken, Connie S., Reichling, Laurie, Ellefson, Jason, Bi, Kun, Riddle, Steven M.

Volltext

Pharmacological Targeting of the Pseudokinase Her3 von Xie, Ting, Lim, Sang Min, Westover, Kenneth D, Dodge, Michael E, Ercan, Dalia, Ficarro, Scott B, Udayakumar, Durga, Gurbani, Deepak, Tae, Hyun Seop, Riddle, Steven M, Sim, Taebo, Marto, Jarrod A, Jänne, Pasi A, Crews, Craig M, Gray, Nathanael S

Volltext